Comprehensive Analysis of PPARα‐Dependent Regulation of Hepatic Lipid Metabolism by Expression Profiling M Rakhshandehroo, LM Sanderson, M Matilainen, R Stienstra, ... PPAR research 2007 (1), 026839, 2007 | 269 | 2007 |
DICKKOPF-4 is induced by TCF/β-catenin and upregulated in human colon cancer, promotes tumour cell invasion and angiogenesis and is repressed by 1α, 25-dihydroxyvitamin D3 N Pendás-Franco, JM García, C Peña, N Valle, HG Pálmer, M Heinäniemi, ... Oncogene 27 (32), 4467-4477, 2008 | 205 | 2008 |
Systems genomics evaluation of the SH-SY5Y neuroblastoma cell line as a model for Parkinson’s disease A Krishna, M Biryukov, C Trefois, PMA Antony, R Hussong, J Lin, ... BMC genomics 15, 1-21, 2014 | 200 | 2014 |
Role of the Keap1–Nrf2 pathway in cancer HM Leinonen, E Kansanen, P Pölönen, M Heinäniemi, AL Levonen Advances in cancer research 122, 281-320, 2014 | 194 | 2014 |
Immunogenomic landscape of hematological malignancies O Dufva, P Pölönen, O Brück, MAI Keränen, J Klievink, J Mehtonen, ... Cancer Cell 38 (3), 380-399. e13, 2020 | 173 | 2020 |
Phenotype-based drug screening reveals association between venetoclax response and differentiation stage in acute myeloid leukemia H Kuusanmäki, AM Leppä, P Pölönen, M Kontro, O Dufva, D Deb, ... Haematologica 105 (3), 708, 2019 | 156 | 2019 |
Gene-pair expression signatures reveal lineage control M Heinäniemi, M Nykter, R Kramer, A Wienecke-Baldacchino, ... Nature methods 10 (6), 577-583, 2013 | 148 | 2013 |
Profiling of promoter occupancy by PPARα in human hepatoma cells via ChIP-chip analysis DLM van der Meer, T Degenhardt, S Väisänen, PJ de Groot, ... Nucleic acids research 38 (9), 2839-2850, 2010 | 144 | 2010 |
Regulation of multiple insulin-like growth factor binding protein genes by 1α,25-dihydroxyvitamin D3 M Matilainen, M Malinen, K Saavalainen, C Carlberg Nucleic Acids Research 33 (17), 5521-5532, 2005 | 125 | 2005 |
HOXA9 cooperates with activated JAK/STAT signaling to drive leukemia development CE de Bock, S Demeyer, S Degryse, D Verbeke, B Sweron, O Gielen, ... Cancer discovery 8 (5), 616-631, 2018 | 105 | 2018 |
Meta-analysis of primary target genes of peroxisome proliferator-activated receptors M Heinäniemi, JO Uski, T Degenhardt, C Carlberg Genome biology 8, 1-29, 2007 | 102 | 2007 |
Structural determinants of the agonist-independent association of human peroxisome proliferator-activated receptors with coactivators F Molnár, M Matilainen, C Carlberg Journal of Biological Chemistry 280 (28), 26543-26556, 2005 | 100 | 2005 |
Novel insights into the regulation of antioxidant-response-elementmediated gene expression by electrophiles: induction of the transcriptional repressor BACH1 by Nrf2 HK Jyrkkänen, S Kuosmanen, M Heinäniemi, H Laitinen, E Kansanen, ... Biochemical Journal 440 (2), 167-174, 2011 | 93 | 2011 |
Dataset integration identifies transcriptional regulation of microRNA genes by PPARγ in differentiating mouse 3T3-L1 adipocytes E John, A Wienecke-Baldacchino, M Liivrand, M Heinäniemi, C Carlberg, ... Nucleic acids research 40 (10), 4446-4460, 2012 | 92 | 2012 |
Identification of pregnane X receptor binding sites in the regulatory regions of genes involved in bile acid homeostasis C Frank, H Makkonen, TW Dunlop, M Matilainen, S Väisänen, C Carlberg Journal of molecular biology 346 (2), 505-519, 2005 | 92 | 2005 |
Dysregulation of the Keap1–Nrf2 pathway in cancer HM Leinonen, E Kansanen, P Pölönen, M Heinäniemi, AL Levonen Biochemical Society Transactions 43 (4), 645-649, 2015 | 85 | 2015 |
Nrf2 and SQSTM1/p62 jointly contribute to mesenchymal transition and invasion in glioblastoma P Pölönen, A Jawahar Deen, HM Leinonen, HK Jyrkkänen, S Kuosmanen, ... Oncogene 38 (50), 7473-7490, 2019 | 82 | 2019 |
The insulin-like growth factor-binding protein 1 gene is a primary target of peroxisome proliferator-activated receptors T Degenhardt, M Matilainen, KH Herzig, TW Dunlop, C Carlberg Journal of Biological Chemistry 281 (51), 39607-39619, 2006 | 81 | 2006 |
Epigenetic control of a VDR-governed feed-forward loop that regulates p21 ( waf1/cip1 ) expression and function in … JL Thorne, O Maguire, CL Doig, S Battaglia, L Fehr, LE Sucheston, ... Nucleic acids research 39 (6), 2045-2056, 2011 | 79 | 2011 |
Integrated analysis of transcript-level regulation of metabolism reveals disease-relevant nodes of the human metabolic network M Galhardo, L Sinkkonen, P Berninger, J Lin, T Sauter, M Heinäniemi Nucleic acids research 42 (3), 1474-1496, 2014 | 69 | 2014 |