TLR2/MyD88/NF-κB pathway, reactive oxygen species, potassium efflux activates NLRP3/ASC inflammasome during respiratory syncytial virus infection J Segovia, A Sabbah, V Mgbemena, SY Tsai, TH Chang, MT Berton, ... PloS one 7 (1), e29695, 2012 | 272 | 2012 |
DAMP molecule S100A9 acts as a molecular pattern to enhance inflammation during influenza A virus infection: role of DDX21-TRIF-TLR4-MyD88 pathway SY Tsai, JA Segovia, TH Chang, IR Morris, MT Berton, PA Tessier, ... PLoS pathogens 10 (1), e1003848, 2014 | 209 | 2014 |
NLRP3 is a critical regulator of inflammation and innate immune cell response during Mycoplasma pneumoniae infection JA Segovia, TH Chang, VT Winter, JJ Coalson, MP Cagle, L Pandranki, ... Infection and immunity 86 (1), 10.1128/iai. 00548-17, 2018 | 103 | 2018 |
ADP-ribosylation of NLRP3 by Mycoplasma pneumoniae CARDS toxin regulates inflammasome activity S Bose, JA Segovia, SR Somarajan, TH Chang, TR Kannan, JB Baseman MBio 5 (6), 10.1128/mbio. 02186-14, 2014 | 90 | 2014 |
Integrin-mediated first signal for inflammasome activation in intestinal epithelial cells J Thinwa, JA Segovia, S Bose, PH Dube The Journal of Immunology 193 (3), 1373-1382, 2014 | 86 | 2014 |
Cholesterol-rich lipid rafts are required for release of infectious human respiratory syncytial virus particles TH Chang, J Segovia, A Sabbah, V Mgbemena, S Bose Virology 422 (2), 205-213, 2012 | 77 | 2012 |
Integrin activation by the lipid molecule 25-hydroxycholesterol induces a proinflammatory response SM Pokharel, NK Shil, JB Gc, ZT Colburn, SY Tsai, JA Segovia, TH Chang, ... Nature communications 10 (1), 1482, 2019 | 54 | 2019 |
Nedd8 regulates inflammasome-dependent caspase-1 activation JA Segovia, SY Tsai, TH Chang, NK Shil, ST Weintraub, JD Short, S Bose Molecular and cellular biology 35 (3), 582-597, 2015 | 51 | 2015 |
Regulation of TLR3 activation by S100A9 SY Tsai, JA Segovia, TH Chang, NK Shil, SM Pokharel, TR Kannan, ... The Journal of Immunology 195 (9), 4426-4437, 2015 | 42 | 2015 |
Transactivation of inducible nitric oxide synthase gene by Kruppel-like factor 6 regulates apoptosis during influenza A virus infection V Mgbemena, JA Segovia, TH Chang, SY Tsai, GT Cole, CY Hung, ... The Journal of Immunology 189 (2), 606-615, 2012 | 31 | 2012 |
KLF6 and iNOS regulates apoptosis during respiratory syncytial virus infection V Mgbemena, J Segovia, TH Chang, S Bose Cellular immunology 283 (1-2), 1-7, 2013 | 29 | 2013 |
Transcriptional organization of pneumococcal psrP-secY2A2 and impact of GtfA and GtfB deletion on PsrP-associated virulence properties A Lizcano, RAS Babu, AT Shenoy, AM Saville, N Kumar, A D'Mello, ... Microbes and infection 19 (6), 323-333, 2017 | 20 | 2017 |
Krüppel-like factor 6 regulates transforming growth factor-β gene expression during human respiratory syncytial virus infection V Mgbemena, J Segovia, TH Chang, S Bose Virology Journal 8, 1-6, 2011 | 20 | 2011 |
ADP-ribosylation of NLRP3 by Mycoplasma pneumoniae CARDS toxin regulates inflammasome activity. mBio 5: e02186-14 S Bose, JA Segovia, SR Somarajan, TH Chang, TR Kannan, JB Baseman | 7 | 2014 |
Mycoplasma pneumoniae Cards toxin regulates NLRP3 inflammasome activation JA Segovia, S Bose, SR Somarajan, TH Chang, T Kannan, JB Baseman Journal of allergy and clinical immunology 135 (2), AB153, 2015 | 3 | 2015 |
Mycoplasma pneumoniae CARDS toxin is a unique virulence factor targeting the Th1/Th2 response for persistent infection JA Segovia, TH Chang, MP Cagle, VT Winter, JJ Coalson, TR Kannan, ... The Journal of Immunology 198 (1_Supplement), 131.15-131.15, 2017 | 1 | 2017 |
Kruppel-like factor 6 and inducible nitric oxide synthase regulates apoptosis during respiratory syncytial virus infection (P6198) J Segovia, V Mgbemena, TH Chang, S Bose The Journal of Immunology 190 (1_Supplement), 189.14-189.14, 2013 | 1 | 2013 |
Role of Mycoplasma pneumoniae CARDS toxin in inducing mitochondrial damage and inflammation. AM Benavides, NS Liendo, JA Segovia The Journal of Immunology 208 (1_Supplement), 105.16-105.16, 2022 | | 2022 |
Effects of Mycoplasma pneumoniae CARDS Toxin on mitochondrial homeostasis NS Liendo, AM Benavides, J Segovia The Journal of Immunology 208 (1_Supplement), 105.17-105.17, 2022 | | 2022 |
CARDS toxin is critical for mediating the early inflammatory response during Mycoplasma pneumoniae infection JA Segovia, SR Somorajan, MP Cagle, JB Baseman, TR Kannan The Journal of Immunology 200 (1_Supplement), 114.28-114.28, 2018 | | 2018 |