Neuropathic pain creates an enduring prefrontal cortex dysfunction corrected by the type II diabetic drug metformin but not by gabapentin S Shiers, G Pradhan, J Mwirigi, G Mejia, A Ahmad, S Kroener, T Price Journal of Neuroscience 38 (33), 7337-7350, 2018 | 78 | 2018 |
Reversal of peripheral nerve injury-induced neuropathic pain and cognitive dysfunction via genetic and tomivosertib targeting of MNK S Shiers, J Mwirigi, G Pradhan, M Kume, B Black, P Barragan-Iglesias, ... Neuropsychopharmacology 45 (3), 524-533, 2020 | 45 | 2020 |
A pharmacological interactome between COVID-19 patient samples and human sensory neurons reveals potential drivers of neurogenic pulmonary dysfunction PR Ray, A Wangzhou, N Ghneim, MS Yousuf, C Paige, ... Brain, behavior, and immunity 89, 559-568, 2020 | 42 | 2020 |
The cellular basis of protease-activated receptor 2–evoked mechanical and affective pain SN Hassler, M Kume, JM Mwirigi, A Ahmad, S Shiers, A Wangzhou, ... JCI insight 5 (11), 2020 | 25 | 2020 |
Harmonized cross-species cell atlases of trigeminal and dorsal root ganglia SA Bhuiyan, M Xu, L Yang, E Semizoglou, P Bhatia, KI Pantaleo, ... bioRxiv, 2023 | 10 | 2023 |
A role for protease activated receptor type 3 (PAR3) in nociception demonstrated through development of a novel peptide agonist J Mwirigi, M Kume, SN Hassler, A Ahmad, PR Ray, C Jiang, ... The journal of pain 22 (6), 692-706, 2021 | 9 | 2021 |
MNK inhibitor eFT508 (Tomivosertib) suppresses ectopic activity in human dorsal root ganglion neurons from dermatomes with radicular neuropathic pain Y Li, ML Uhelski, RY North, JM Mwirigi, CE Tatsui, JP Cata, G Corrales, ... bioRxiv, 2023 | 4 | 2023 |
Inducible co-stimulatory molecule (ICOS) alleviates paclitaxel-induced neuropathic pain via an IL-10-mediated mechanism in female mice I Sankaranarayanan, D Tavares-Ferreira, JM Mwirigi, GL Mejia, ... Journal of Neuroinflammation 20 (1), 32, 2023 | 4 | 2023 |
Meteorin alleviates paclitaxel-induced peripheral neuropathic pain in mice I Sankaranarayanan, D Tavares-Ferreira, L He, M Kume, JM Mwirigi, ... The Journal of Pain 24 (4), 555-567, 2023 | 2 | 2023 |
RNA isoform expression landscape of the human dorsal root ganglion (DRG) generated from long read sequencing A Arendt-Tranholm, JM Mwirigi, TJ Price bioRxiv, 2023 | 1 | 2023 |
Oncostatin M induces nociceptive signaling in human dorsal root ganglia J Mwirigi, UM Franco-Enzastiga, I Sankaranarayanan, D Tavares-Ferreira, ... The Journal of Pain 24 (4), 16, 2023 | 1 | 2023 |
Exploring the Single-Cell Transcriptome Landscape of the Human Dorsal Root Ganglion in Diabetic Peripheral Neuropathy I Sankaranarayanan, JM Mwirigi, NN Inturi, D Tavares-Ferreira, TJ Price The Journal of Pain 25 (4), 26, 2024 | | 2024 |
Protocol for long read sequencing of dorsal root ganglia from human organ donors A Arendt-Tranholm, JM Mwirigi, T Price | | 2024 |
Elevations in the Mitochondrial Matrix Protein Cyclophilin D Correlate With Reduced Parvalbumin Expression in the Prefrontal Cortex of Patients With Schizophrenia JT O’Brien, SP Jalilvand, NA Suji, RK Jupelly, A Phensy, JM Mwirigi, ... Schizophrenia Bulletin, sbae016, 2024 | | 2024 |
Interleukin-6 induces nascent protein synthesis in human DRG nociceptors via MNK-eIF4E signaling ME Mitchell, G Torrijos, LF Cook, JM Mwirigi, L He, S Shiers, TJ Price bioRxiv, 2024.04. 04.588080, 2024 | | 2024 |
Genetic editing of primary human dorsal root ganglion neurons using CRISPR-Cas9 with functional confirmation SM Palomino, K Gabriel, J Mwirigi, A Cervantes, P Horton, G Funk, ... bioRxiv, 2024.04. 02.587857, 2024 | | 2024 |
Epigenomic landscape of the human dorsal root ganglion: sex differences and transcriptional regulation of nociceptive genes Ú Franco-Enzástiga, NN Inturi, K Natarajan, JM Mwirigi, K Mazhar, ... bioRxiv, 2024.03. 27.587047, 2024 | | 2024 |
VLK drives extracellular phosphorylation of EphB2 to govern the EphB2-NMDAR interaction and injury-induced pain KD Srikanth, H Elahi, P Chander, HR Washburn, S Hassler, JM Mwirigi, ... bioRxiv, 2024.03. 18.585314, 2024 | | 2024 |
The mitochondrial matrix protein cyclophilin D contributes to deficits in parvalbumin interneurons in schizophrenia JT O'Brien, SP Jalilvand, NA Suji, A Phensy, RK Jupelly, JM Mwirigi, ... bioRxiv, 2023.05. 19.541499, 2023 | | 2023 |
Meteorin alleviates Paclitaxel-induced peripheral neuropathy in mice I Sankaranarayanan, D Tavares-Ferreira, L He, M Kume, J Mwirigi, ... bioRxiv, 2022.09. 13.507857, 2022 | | 2022 |