| Functional impairment of myeloid and plasmacytoid dendritic cells of patients with chronic hepatitis B RG van der Molen, D Sprengers, RS Binda, EC de Jong, HGM Niesters, ... Hepatology 40 (3), 738-746, 2004 | 401 | 2004 |
| Antibodies against immune checkpoint molecules restore functions of tumor-infiltrating T cells in hepatocellular carcinomas G Zhou, D Sprengers, PPC Boor, M Doukas, H Schutz, S Mancham, ... Gastroenterology 153 (4), 1107-1119. e10, 2017 | 369 | 2017 |
| Lactobacillus GG prevents recurrence of colitis in HLA-B27 transgenic rats after antibiotic treatment LA Dieleman, MS Goerres, A Arends, D Sprengers, C Torrice, F Hoentjen, ... Gut 52 (3), 370-376, 2003 | 281 | 2003 |
| Activated tumor‐infiltrating CD4+ regulatory T cells restrain antitumor immunity in patients with primary or metastatic liver cancer A Pedroza‐Gonzalez, C Verhoef, JNM Ijzermans, MP Peppelenbosch, ... Hepatology 57 (1), 183-194, 2013 | 205 | 2013 |
| Modeling rotavirus infection and antiviral therapy using primary intestinal organoids Y Yin, M Bijvelds, W Dang, L Xu, AA van der Eijk, K Knipping, N Tuysuz, ... Antiviral research 123, 120-131, 2015 | 181 | 2015 |
| Surveillance for hepatocellular carcinoma is associated with increased survival: results from a large cohort in the Netherlands S van Meer, RA de Man, MJ Coenraad, D Sprengers, KMJ van Nieuwkerk, ... Journal of hepatology 63 (5), 1156-1163, 2015 | 154 | 2015 |
| Flares in chronic hepatitis B patients induced by the host or the virus? Relation to treatment response during Peg-interferon α-2b therapy HJ Flink, D Sprengers, BE Hansen, M van Zonneveld, RA De Man, ... Gut 54 (11), 1604-1609, 2005 | 145 | 2005 |
| PD-L1, Galectin-9 and CD8+ tumor-infiltrating lymphocytes are associated with survival in hepatocellular carcinoma K Sideras, K Biermann, J Verheij, BR Takkenberg, S Mancham, ... Oncoimmunology 6 (2), e1273309, 2017 | 137 | 2017 |
| TIGIT, the next step towards successful combination immune checkpoint therapy in cancer Z Ge, MP Peppelenbosch, D Sprengers, J Kwekkeboom Frontiers in immunology 12, 699895, 2021 | 134 | 2021 |
| Cancer-associated fibroblasts provide a stromal niche for liver cancer organoids that confers trophic effects and therapy resistance J Liu, P Li, L Wang, M Li, Z Ge, L Noordam, R Lieshout, MMA Verstegen, ... Cellular and molecular gastroenterology and hepatology 11 (2), 407-431, 2021 | 123 | 2021 |
| Hepatitis E virus infects neurons and brains X Zhou, F Huang, L Xu, Z Lin, FMS de Vrij, AC Ayo-Martin, ... The Journal of infectious diseases 215 (8), 1197-1206, 2017 | 119 | 2017 |
| Tumor-infiltrating plasmacytoid dendritic cells promote immunosuppression by Tr1 cells in human liver tumors A Pedroza-Gonzalez, G Zhou, E Vargas-Mendez, PPC Boor, S Mancham, ... Oncoimmunology 4 (6), e1008355, 2015 | 116 | 2015 |
| Favorable effect of adefovir on the number and functionality of myeloid dendritic cells of patients with chronic HBV RG van der Molen, D Sprengers, PJ Biesta, JG Kusters, HLA Janssen Hepatology 44 (4), 907-914, 2006 | 99 | 2006 |
| α-Galactosylceramide in chronic hepatitis B infection: results from a randomized placebo-controlled Phase I/II trial AM Woltman, MJ Ter Borg, RS Binda, D Sprengers, BME von Blomberg, ... Antiviral therapy 14 (6), 809-818, 2009 | 98 | 2009 |
| Reduction of immunosuppressive tumor microenvironment in cholangiocarcinoma by ex vivo targeting immune checkpoint molecules G Zhou, D Sprengers, S Mancham, R Erkens, PPC Boor, AA van Beek, ... Journal of hepatology 71 (4), 753-762, 2019 | 96 | 2019 |
| Bleeding time in patients with hepatic cirrhosis. JC Blake, D Sprengers, P Grech, PA McCormick, N McIntyre, ... British Medical Journal 301 (6742), 12-15, 1990 | 92 | 1990 |
| Multiple biopsy passes and the risk of complications of percutaneous liver biopsy H Chi, BE Hansen, WY Tang, JNL Schouten, D Sprengers, P Taimr, ... European journal of gastroenterology & hepatology 29 (1), 36-41, 2017 | 87 | 2017 |
| Cross talk between nucleotide synthesis pathways with cellular immunity in constraining hepatitis E virus replication Y Wang, W Wang, L Xu, X Zhou, E Shokrollahi, K Felczak, ... Antimicrobial agents and chemotherapy 60 (5), 2834-2848, 2016 | 82 | 2016 |
| Different composition of intrahepatic lymphocytes in the immune‐tolerance and immune‐clearance phase of chronic hepatitis B D Sprengers, RG Van der Molen, JG Kusters, B Hansen, HGM Niesters, ... Journal of medical virology 78 (5), 561-568, 2006 | 77 | 2006 |
| Mitochondrial fusion via OPA1 and MFN1 supports liver tumor cell metabolism and growth M Li, L Wang, Y Wang, S Zhang, G Zhou, R Lieshout, B Ma, J Liu, C Qu, ... Cells 9 (1), 121, 2020 | 74 | 2020 |
Luc van der LaanProfessor at Erasmus MC-University Medical center RotterdamVerified email at erasmusmc.nl
