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Nathan G. Dolloff
Nathan G. Dolloff
Associate Professor, MUSC
Verifierad e-postadress på musc.edu
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Dual inactivation of Akt and ERK by TIC10 signals Foxo3a nuclear translocation, TRAIL gene induction, and potent antitumor effects
JE Allen, G Krigsfeld, PA Mayes, L Patel, DT Dicker, AS Patel, NG Dolloff, ...
Science translational medicine 5 (171), 171ra17-171ra17, 2013
3122013
CX3CR1-fractalkine expression regulates cellular mechanisms involved in adhesion, migration, and survival of human prostate cancer cells
SA Shulby, NG Dolloff, ME Stearns, O Meucci, A Fatatis
Cancer research 64 (14), 4693-4698, 2004
2312004
CDK1 stabilizes HIF-1α via direct phosphorylation of Ser668 to promote tumor growth
NA Warfel, NG Dolloff, DT Dicker, J Malysz, WS El-Deiry
Cell cycle 12 (23), 3689-3701, 2013
1472013
Beyond the CRAB symptoms: a study of presenting clinical manifestations of multiple myeloma
G Talamo, U Farooq, M Zangari, J Liao, NG Dolloff, TP Loughran Jr, ...
Clinical Lymphoma Myeloma and Leukemia 10 (6), 464-468, 2010
1252010
Glutaminase inhibitor CB-839 synergizes with carfilzomib in resistant multiple myeloma cells
RM Thompson, D Dytfeld, L Reyes, RM Robinson, B Smith, Y Manevich, ...
Oncotarget 8 (22), 35863, 2017
1112017
Profiling bortezomib resistance identifies secondary therapies in a mouse myeloma model
HAF Stessman, LB Baughn, A Sarver, T Xia, R Deshpande, A Mansoor, ...
Molecular cancer therapeutics 12 (6), 1140-1150, 2013
902013
Bone-metastatic potential of human prostate cancer cells correlates with Akt/PKB activation by α platelet-derived growth factor receptor
NG Dolloff, SS Shulby, AV Nelson, ME Stearns, GJ Johannes, JD Thomas, ...
Oncogene 24 (45), 6848-6854, 2005
892005
The p53 target Plk2 interacts with TSC proteins impacting mTOR signaling, tumor growth, and chemosensitivity under hypoxic conditions
EM Matthew, LS Hart, A Astrinidis, A Navaraj, NG Dolloff, DT Dicker, ...
Cell Cycle 8 (24), 4168-4175, 2009
832009
Human colon cancer stem cells are enriched by insulin-like growth factor-1 and are sensitive to figitumumab
LS Hart, NG Dolloff, DT Dicker, C Koumenis, JG Christensen, A Grimberg, ...
Cell cycle 10 (14), 2331-2338, 2011
692011
ERK and MDM2 prey on FOXO3a
W Yang, NG Dolloff, WS El-Deiry
nature cell biology 10 (2), 125-126, 2008
652008
Quinacrine sensitizes hepatocellular carcinoma cells to TRAIL and chemotherapeutic agents
W Wang, JN Gallant, SI Katz, NG Dolloff, CD Smith, J Abdulghani, ...
Cancer biology & therapy 12 (3), 229-238, 2011
562011
Human Bone Marrow Activates the Akt Pathway in Metastatic Prostate Cells through Transactivation of the α-Platelet–Derived Growth Factor Receptor
NG Dolloff, MR Russell, N Loizos, A Fatatis
Cancer research 67 (2), 555-562, 2007
552007
The α-receptor for platelet-derived growth factor as a target for antibody-mediated inhibition of skeletal metastases from prostate cancer cells
MR Russell, WL Jamieson, NG Dolloff, A Fatatis
Oncogene 28 (3), 412-421, 2009
472009
Inhibitors of the protein disulfide isomerase family for the treatment of multiple myeloma
RM Robinson, L Reyes, RM Duncan, H Bian, AB Reitz, Y Manevich, ...
Leukemia 33 (4), 1011-1022, 2019
462019
Quinacrine synergizes with 5-fluorouracil and other therapies in colorectal cancer
JN Gallant, JE Allen, CD Smith, DT Dicker, W Wang, NG Dolloff, A Navaraj, ...
Cancer biology & therapy 12 (3), 239-251, 2011
462011
Off-target lapatinib activity sensitizes colon cancer cells through TRAIL death receptor up-regulation
NG Dolloff, PA Mayes, LS Hart, DT Dicker, R Humphreys, WS El-Deiry
Science translational medicine 3 (86), 86ra50-86ra50, 2011
462011
Design of hydrazide-bearing HDACIs based on panobinostat and their p53 and FLT3-ITD dependency in antileukemia activity
X Li, Y Jiang, YK Peterson, T Xu, RA Himes, X Luo, G Yin, ES Inks, ...
Journal of medicinal chemistry 63 (10), 5501-5525, 2020
442020
Overcoming hypoxia-induced apoptotic resistance through combinatorial inhibition of GSK-3β and CDK1
PA Mayes, NG Dolloff, CJ Daniel, JJ Liu, LS Hart, K Kuribayashi, JE Allen, ...
Cancer research 71 (15), 5265-5275, 2011
372011
Targeted therapy of multiple myeloma
NG Dolloff, G Talamo
Impact of Genetic Targets on Cancer Therapy, 197-221, 2013
342013
Prozone effect of serum IgE levels in a case of plasma cell leukemia
G Talamo, W Castellani, NG Dolloff
Journal of hematology & oncology 3, 1-3, 2010
282010
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Artiklar 1–20