| Mitochondrial DNA mutations in human colonic crypt stem cells RW Taylor, MJ Barron, GM Borthwick, A Gospel, PF Chinnery, ... The Journal of clinical investigation 112 (9), 1351-1360, 2003 | 550 | 2003 |
| Chronic inflammation induces telomere dysfunction and accelerates ageing in mice D Jurk, C Wilson, JF Passos, F Oakley, C Correia-Melo, L Greaves, ... Nature communications 5, 4172, 2014 | 463 | 2014 |
| Mitochondria are required for pro‐ageing features of the senescent phenotype C Correia‐Melo, FDM Marques, R Anderson, G Hewitt, R Hewitt, J Cole, ... The EMBO journal 35 (7), 724-742, 2016 | 296 | 2016 |
| Mitochondrial DNA and disease LC Greaves, AK Reeve, RW Taylor, DM Turnbull The Journal of pathology 226 (2), 274-286, 2012 | 293 | 2012 |
| Mitochondrial DNA mutations are established in human colonic stem cells, and mutated clones expand by crypt fission LC Greaves, SL Preston, PJ Tadrous, RW Taylor, MJ Barron, D Oukrif, ... Proceedings of the National Academy of Sciences 103 (3), 714-719, 2006 | 284 | 2006 |
| Mechanisms of field cancerization in the human stomach: the expansion and spread of mutated gastric stem cells SAC McDonald, LC Greaves, L Gutierrez–Gonzalez, M Rodriguez–Justo, ... Gastroenterology 134 (2), 500-510, 2008 | 234 | 2008 |
| Locating the stem cell niche and tracing hepatocyte lineages in human liver TG Fellous, S Islam, PJ Tadrous, G Elia, HM Kocher, S Bhattacharya, ... Hepatology 49 (5), 1655-1663, 2009 | 166 | 2009 |
| Interactions of skin thickness and physicochemical properties of test compounds in percutaneous penetration studies SC Wilkinson, WJM Maas, JB Nielsen, LC Greaves, JJM van de Sandt, ... International archives of occupational and environmental health 79 (5), 405-413, 2006 | 107 | 2006 |
| The ageing mitochondrial genome KJ Krishnan, LC Greaves, AK Reeve, D Turnbull Nucleic acids research 35 (22), 7399-7405, 2007 | 104 | 2007 |
| Length‐independent telomere damage drives post‐mitotic cardiomyocyte senescence R Anderson, A Lagnado, D Maggiorani, A Walaszczyk, E Dookun, ... The EMBO journal 38 (5), e100492, 2019 | 96 | 2019 |
| Clonal expansion of early to mid-life mitochondrial DNA point mutations drives mitochondrial dysfunction during human ageing LC Greaves, M Nooteboom, JL Elson, HAL Tuppen, GA Taylor, ... PLoS Genet 10 (9), e1004620, 2014 | 92 | 2014 |
| Mitochondrial DNA mutations and aging KJ Krishnan, LC Greaves, AK Reeve, DM Turnbull Annals of the New York Academy of Sciences 1100 (1), 227-240, 2007 | 78 | 2007 |
| A methodological approach to tracing cell lineage in human epithelial tissues TG Fellous, SAC McDonald, J Burkert, A Humphries, S Islam, ... Stem Cells 27 (6), 1410-1420, 2009 | 72 | 2009 |
| In situ lineage tracking of human prostatic epithelial stem cell fate reveals a common clonal origin for basal and luminal cells JK Blackwood, SC Williamson, LC Greaves, L Wilson, AC Rigas, ... The Journal of pathology 225 (2), 181-188, 2011 | 66 | 2011 |
| A phenotype-driven approach to generate mouse models with pathogenic mtDNA mutations causing mitochondrial disease JHK Kauppila, HL Baines, A Bratic, ML Simard, C Freyer, A Mourier, ... Cell reports 16 (11), 2980-2990, 2016 | 61 | 2016 |
| Mitochondrial DNA defects and selective extraocular muscle involvement in CPEO LC Greaves, P Yu-Wai-Man, EL Blakely, KJ Krishnan, NE Beadle, J Kerin, ... Investigative ophthalmology & visual science 51 (7), 3340-3346, 2010 | 60 | 2010 |
| Comparison of mitochondrial mutation spectra in ageing human colonic epithelium and disease: absence of evidence for purifying selection in somatic mitochondrial DNA point … LC Greaves, JL Elson, M Nooteboom, JP Grady, GA Taylor, RW Taylor, ... PLoS Genet 8 (11), e1003082, 2012 | 59 | 2012 |
| Quantification of mitochondrial DNA mutation load LC Greaves, NE Beadle, GA Taylor, D Commane, JC Mathers, K Khrapko, ... Aging cell 8 (5), 566-572, 2009 | 59 | 2009 |
| Age‐associated mitochondrial DNA mutations lead to small but significant changes in cell proliferation and apoptosis in human colonic crypts M Nooteboom, R Johnson, RW Taylor, NA Wright, RN Lightowlers, ... Aging cell 9 (1), 96-99, 2010 | 58 | 2010 |
| Mitochondrial DNA mutations and ageing LC Greaves, DM Turnbull Biochimica et Biophysica Acta (BBA)-General Subjects 1790 (10), 1015-1020, 2009 | 57 | 2009 |
