Jason Wright
Jason Wright
Homology Medicines
Verified email at homologymedicines.com
Title
Cited by
Cited by
Year
Genome engineering using the CRISPR-Cas9 system
FA Ran, PD Hsu, J Wright, V Agarwala, DA Scott, F Zhang
Nature protocols 8 (11), 2281-2308, 2013
143492013
Upregulation of c-MYC in cis through a large chromatin loop linked to a cancer risk-associated single-nucleotide polymorphism in colorectal cancer cells
JB Wright, SJ Brown, MD Cole
Molecular and cellular biology 30 (6), 1411-1420, 2010
2732010
Breast cancer risk–associated SNPs modulate the affinity of chromatin for FOXA1 and alter gene expression
R Cowper-Sal, X Zhang, JB Wright, SD Bailey, MD Cole, J Eeckhoute, ...
Nature genetics 44 (11), 1191-1198, 2012
2422012
Genome-scale activation screen identifies a lncRNA locus regulating a gene neighbourhood
J Joung, JM Engreitz, S Konermann, OO Abudayyeh, VK Verdine, F Aguet, ...
Nature 548 (7667), 343-346, 2017
2272017
High-resolution interrogation of functional elements in the noncoding genome.
ZF Sanjana NE*, Wright JB*, Zheng K, Shalem O, Fontanillas P, Joung J, Cheng ...
Science 353 (6307), 1545-1549, 2016
2242016
Genome-wide analyses implicate 33 loci in heritable dog osteosarcoma, including regulatory variants near CDKN2A/B
EK Karlsson, S Sigurdsson, E Ivansson, R Thomas, I Elvers, J Wright, ...
Genome biology 14 (12), 1-16, 2013
1192013
Myc protein is stabilized by suppression of a novel E3 ligase complex in cancer cells
SH Choi, JB Wright, SA Gerber, MD Cole
Genes & development 24 (12), 1236-1241, 2010
1032010
Discovery of proteins associated with a predefined genomic locus via dCas9–APEX-mediated proximity labeling
SA Myers, J Wright, R Peckner, BT Kalish, F Zhang, SA Carr
Nature methods 15 (6), 437-439, 2018
832018
IGF2 mRNA binding protein-2 is a tumor promoter that drives cancer proliferation through its client mRNAs IGF2 and HMGA1
JA Ning Dai, Fei Ji, Jason Wright, Liliana Minichiello, Ruslan I Sadreyev
eLife, 2017
49*2017
CRISPR screens to discover functional noncoding elements
JB Wright, NE Sanjana
Trends in Genetics 32 (9), 526-529, 2016
292016
Distal interleukin-1β (IL-1β) response element of human matrix metalloproteinase-13 (MMP-13) binds activator protein 1 (AP-1) transcription factors and regulates gene expression
AC Schmucker, JB Wright, MD Cole, CE Brinckerhoff
Journal of Biological Chemistry 287 (2), 1189-1197, 2012
282012
Stem cell-derived clade F AAVs mediate high-efficiency homologous recombination-based genome editing
LJ Smith, J Wright, G Clark, T Ul-Hasan, X Jin, A Fong, M Chandra, ...
Proceedings of the National Academy of Sciences 115 (31), E7379-E7388, 2018
202018
Histone acetylation of glucose-induced thioredoxin-interacting protein gene expression in pancreatic islets
P Bompada, D Atac, C Luan, R Andersson, JD Omella, EO Laakso, ...
The international journal of biochemistry & cell biology 81, 82-91, 2016
162016
CRISPR/Cas9-APEX-mediated proximity labeling enables discovery of proteins associated with a predefined genomic locus in living cells
SAC Samuel A. Myers, Jason Wright, Feng Zhang
BioRxiv, 2017
52017
Retroviruses hijack chromatin loops to drive oncogene expression and highlight the chromatin architecture around proto-oncogenic loci
JM Pattison, JB Wright, MD Cole
PloS one 10 (3), e0120256, 2015
52015
Nuclease-free and promoter-less AAVHSC-mediated genome editing in vivo corrects the disease phenotype in a mouse model of phenylketonuria
J Wright, JL Ellsworth, T St Martin, L Smith, L Adamson-Small, L Benard, ...
Molecular therapy 27 (4), 462-463, 2019
32019
Molecular characterization of precise in vivo targeted gene integration in human cells using AAVHSC15
HM Chen, R Resendes, A Ghodssi, D Sookiasian, M Tian, S Dollive, ...
PloS one 15 (5), e0233373, 2020
12020
Adeno-associated virus compositions for pah gene transfer and methods of use thereof
AB Seymour, SS Ahmed, JB Wright, SN Dollive, H Rubin
US Patent App. 16/824,008, 2020
2020
Adeno-associated virus compositions for pah gene transfer and methods of use thereof
AB Seymour, SS Ahmed, JB Wright, SN Dollive, H Rubin
US Patent App. 16/798,890, 2020
2020
Adeno-associated virus compositions for PAH gene transfer and methods of use thereof
AB Seymour, SS Ahmed, JB Wright, SN Dollive, H Rubin
US Patent 10,610,606, 2020
2020
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