| Genome engineering using the CRISPR-Cas9 system F Ran, PD Hsu, J Wright, V Agarwala, DA Scott, F Zhang Nature protocols 8 (11), 2281-2308, 2013 | 11769 | 2013 |
| Genome-scale activation screen identifies a lncRNA locus regulating a gene neighbourhood J Joung, JM Engreitz, S Konermann, OO Abudayyeh, VK Verdine, F Aguet, ... Nature 548 (7667), 343-346, 2017 | 401 | 2017 |
| Breast cancer risk–associated SNPs modulate the affinity of chromatin for FOXA1 and alter gene expression R Cowper-Sal· lari, X Zhang, JB Wright, SD Bailey, MD Cole, J Eeckhoute, ... Nature genetics 44 (11), 1191-1198, 2012 | 328 | 2012 |
| High-resolution interrogation of functional elements in the noncoding genome. ZF Sanjana NE*, Wright JB*, Zheng K, Shalem O, Fontanillas P, Joung J, Cheng ... Science 353 (6307), 1545-1549, 2016 | 312 | 2016 |
| Upregulation of c-MYC in cis through a large chromatin loop linked to a cancer risk-associated single-nucleotide polymorphism in colorectal cancer cells JB Wright, SJ Brown, MD Cole Molecular and cellular biology, 2010 | 312 | 2010 |
| Genome-wide analyses implicate 33 loci in heritable dog osteosarcoma, including regulatory variants near CDKN2A/B EK Karlsson, S Sigurdsson, E Ivansson, R Thomas, I Elvers, J Wright, ... Genome biology 14, 1-16, 2013 | 172 | 2013 |
| Discovery of proteins associated with a predefined genomic locus via dCas9–APEX-mediated proximity labeling SA Myers, J Wright, R Peckner, BT Kalish, F Zhang, SA Carr Nature methods 15 (6), 437-439, 2018 | 155 | 2018 |
| Myc protein is stabilized by suppression of a novel E3 ligase complex in cancer cells SH Choi, JB Wright, SA Gerber, MD Cole Genes & development 24 (12), 1236-1241, 2010 | 127 | 2010 |
| IGF2 mRNA binding protein-2 is a tumor promoter that drives cancer proliferation through its client mRNAs IGF2 and HMGA1 JA Ning Dai, Fei Ji, Jason Wright, Liliana Minichiello, Ruslan I Sadreyev eLife, 2017 | 97* | 2017 |
| CRISPR screens to discover functional noncoding elements JB Wright, NE Sanjana Trends in Genetics 32 (9), 526-529, 2016 | 43 | 2016 |
| Stem cell-derived clade F AAVs mediate high-efficiency homologous recombination-based genome editing LJ Smith, J Wright, G Clark, T Ul-Hasan, X Jin, A Fong, M Chandra, ... Proceedings of the National Academy of Sciences 115 (31), E7379-E7388, 2018 | 35 | 2018 |
| Distal interleukin-1β (IL-1β) response element of human matrix metalloproteinase-13 (MMP-13) binds activator protein 1 (AP-1) transcription factors and regulates gene expression AC Schmucker, JB Wright, MD Cole, CE Brinckerhoff Journal of Biological Chemistry 287 (2), 1189-1197, 2012 | 33 | 2012 |
| Histone acetylation of glucose-induced thioredoxin-interacting protein gene expression in pancreatic islets P Bompada, D Atac, C Luan, R Andersson, JD Omella, EO Laakso, ... The international journal of biochemistry & cell biology 81, 82-91, 2016 | 23 | 2016 |
| Molecular characterization of precise in vivo targeted gene integration in human cells using AAVHSC15 HM Chen, R Resendes, A Ghodssi, D Sookiasian, M Tian, S Dollive, ... Plos one 15 (5), e0233373, 2020 | 11 | 2020 |
| Functional genomics using CRISPR-Cas systems for saturating mutagenesis of non-coding elements, compositions, methods, libraries and applications thereof DE Bauer, SH Orkin, NE Sanjana, O Shalem, J Wright, F Zhang US Patent 11,685,917, 2023 | 8 | 2023 |
| Adeno-associated virus compositions for PAH gene transfer and methods of use thereof AB Seymour, SS Ahmed, JB Wright, SN Dollive, H Rubin US Patent 10,610,606, 2020 | 6 | 2020 |
| CRISPR/Cas9-APEX-mediated proximity labeling enables discovery of proteins associated with a predefined genomic locus in living cells SAC Samuel A. Myers, Jason Wright, Feng Zhang BioRxiv, 2017 | 6 | 2017 |
| Retroviruses hijack chromatin loops to drive oncogene expression and highlight the chromatin architecture around proto-oncogenic loci JM Pattison, JB Wright, MD Cole PLoS One 10 (3), e0120256, 2015 | 6 | 2015 |
| Proteogenomic insights suggest druggable pathways in endometrial carcinoma Y Dou, L Katsnelson, MA Gritsenko, Y Hu, B Reva, R Hong, YT Wang, ... Cancer cell 41 (9), 1586-1605. e15, 2023 | 4 | 2023 |
| LNA blockers for improved amplification selectivity J Prout, M Tian, A Palladino, J Wright, JF Thompson Scientific Reports 13 (1), 4858, 2023 | 4 | 2023 |
