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Fredrik Bjorkling
Fredrik Bjorkling
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Verifierad e-postadress på sund.ku.dk
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A model for interfacial activation in lipases from the structure of a fungal lipase-inhibitor complex
L Brzozowski, A.M., Derewenda, U., Derewenda, Z.S., Dodson, G., Lawson, D ...
Nature 351, 491-497, 1991
13791991
The future impact of industrial lipases
F Björkling, SE Godtfredsen, O Kirk
Trends in Biotechnology 9 (1), 360-363, 1991
3461991
Lipase catalyzed synthesis of peroxycarboxylic acids and lipase mediated oxidations.
F Björkling, H Frykman, SE Godtfredsen, O Kirk
Tetrahedron 48 (22), 4587-4592, 1992
2781992
Enzyme catalysed preparation of 6-O-acylglucopyranosides
K Adelhorst, F Björkling, SE Godtfredsen, O Kirk
Synthesis 1990 (02), 112-115, 1990
1971990
Lipase-mediated formation of peroxycarboxylic acids used in catalytic epoxidation of alkenes
F Björkling, SE Godtfredsen, O Kirk
Journal of the Chemical Society, Chemical Communications, 1301-1303, 1990
1801990
Rapid synthesis of aryl azides from aryl halides under mild conditions
J Andersen, U Madsen, F Björkling, X Liang
Synlett 2005 (14), 2209-2213, 2005
1742005
Anticancer agent CHS-828 inhibits cellular synthesis of NAD
UH Olesen, MK Christensen, F Björkling, M Jäättelä, PB Jensen, ...
Biochemical and biophysical research communications 367 (4), 799-804, 2008
1702008
A highly selective enzyme-catalysed esterification of simple glucosides
F Björkling, SE Godtfredsen, O Kirk
Journal of the Chemical Society, Chemical Communications, 934-935, 1989
1521989
Enzyme catalysed hydrolysis of dialkylated propanedioic acid diesters, chain length dependent reversal of enantioselectivity
F Björkling, J Boutelje, S Gatenbeck, K Hult, T Norin, P Szmulik
Tetrahedron 41 (7), 1347-1352, 1985
1271985
Fatty acid specificity in lipase-catalyzed synthesis of glucoside esters
O Kirk, F Björkling, SE Godtfredsen, TO Larsen
Biocatalysis 6 (2), 127-134, 1992
1231992
Evaluation of the topoisomerase II-inactive bisdioxopiperazine ICRF-161 as a protectant against doxorubicin-induced cardiomyopathy
E Martin, AV Thougaard, M Grauslund, PB Jensen, F Bjorkling, ...
Toxicology 255 (1-2), 72-79, 2009
1202009
Recombinant human PPAR-β/δ ligand-binding domain is locked in an activated conformation by endogenous fatty acids
SA Fyffe, MS Alphey, L Buetow, TK Smith, MAJ Ferguson, MD Sørensen, ...
Journal of molecular biology 356 (4), 1005-1013, 2006
1052006
Synthesis and structure− activity relationship of aminobenzophenones. A novel class of p38 MAP kinase inhibitors with high antiinflammatory activity
ER Ottosen, MD Sørensen, F Björkling, T Skak-Nielsen, MS Fjording, ...
Journal of medicinal chemistry 46 (26), 5651-5662, 2003
982003
Cyclic phosphinamides and phosphonamides, novel series of potent matrix metalloproteinase inhibitors with antitumour activity
MD Sørensen, LKA Blæhr, MK Christensen, T Høyer, S Latini, ...
Bioorganic & medicinal chemistry 11 (24), 5461-5484, 2003
862003
Novel cyanoguanidines with potent oral antitumour activity
C Schou, ER Ottosen, HJ Petersen, F Björkling, S Latini, PV Hjarnaa, ...
Bioorganic & Medicinal Chemistry Letters 7 (24), 3095-3100, 1997
701997
EB1627: a soluble prodrug of the potent anticancer cyanoguanidine CHS828
E Binderup, F Björkling, PV Hjarnaa, S Latini, B Baltzer, M Carlsen, ...
Bioorganic & medicinal chemistry letters 15 (10), 2491-2494, 2005
642005
Synthesis and antitumor effect in vitro and in vivo of substituted 1, 3-dihydroindole-2-ones
MK Christensen, KD Erichsen, C Trojel-Hansen, J Tjørnelund, SJ Nielsen, ...
Journal of medicinal chemistry 53 (19), 7140-7145, 2010
612010
Lipase inhibitors
S Patkar, F Bjorkling
Lipases—their structure, biochemistry and application. Cambridge University …, 1994
561994
Target enzyme mutations are the molecular basis for resistance towards pharmacological inhibition of nicotinamide phosphoribosyltransferase
UH Olesen, JG Petersen, A Garten, W Kiess, J Yoshino, SI Imai, ...
BMC cancer 10, 1-13, 2010
552010
Enzyme catalysed hydrolysis of dialkylated propanedioic acid diesters synthesis of optically pure (S)-α-methylphenylalanine,(S)-α-methyl-tyrosine and (S)-α-methyl-3, 4 …
F Björkling, J Boutelie, S Gatenbeck, K Hult, T Norin
Tetrahedron Letters 26 (40), 4957-4958, 1985
511985
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Artiklar 1–20