| Increased prevalence of circulating novel IL-17 secreting Foxp3 expressing CD4+ T cells and defective suppressive function of circulating Foxp3+ regulatory cells support … A Ueno, H Jijon, R Chan, K Ford, C Hirota, GG Kaplan, PL Beck, M Iacucci, ... Inflammatory bowel diseases 19 (12), 2522-2534, 2013 | 230 | 2013 |
| Neutralizing anti-IL-10 antibody blocks the protective effect of tapeworm infection in a murine model of chemically induced colitis MM Hunter, A Wang, CL Hirota, DM McKay The Journal of Immunology 174 (11), 7368-7375, 2005 | 198 | 2005 |
| TRPM8 activation attenuates inflammatory responses in mouse models of colitis R Ramachandran, E Hyun, L Zhao, TK Lapointe, K Chapman, CL Hirota, ... Proceedings of the National Academy of Sciences 110 (18), 7476-7481, 2013 | 186 | 2013 |
| Cholinergic regulation of epithelial ion transport in the mammalian intestine CL Hirota, DM McKay British journal of pharmacology 149 (5), 463-479, 2006 | 154 | 2006 |
| Smooth muscle hyperplasia/hypertrophy is the most prominent histological change in Crohn’s fibrostenosing bowel strictures: a semiquantitative analysis by using a novel … W Chen, C Lu, C Hirota, M Iacucci, S Ghosh, X Gui Journal of Crohn's and Colitis 11 (1), 92-104, 2017 | 143 | 2017 |
| Profiles of lamina propria T helper cell subsets discriminate between ulcerative colitis and Crohn's disease J Li, A Ueno, M Fort Gasia, J Luider, T Wang, C Hirota, HB Jijon, M Deane, ... Inflammatory bowel diseases 22 (8), 1779-1792, 2016 | 98 | 2016 |
| Differential effects of CB1 neutral antagonists and inverse agonists on gastrointestinal motility in mice MA Storr, M Bashashati, C Hirota, VK Vemuri, CM Keenan, M Duncan, ... Neurogastroenterology & Motility 22 (7), 787-e223, 2010 | 67 | 2010 |
| Proteinase-activated receptor 2 (PAR2) decreases apoptosis in colonic epithelial cells V Iablokov, CL Hirota, MA Peplowski, R Ramachandran, K Mihara, ... Journal of Biological Chemistry 289 (49), 34366-34377, 2014 | 60 | 2014 |
| Proteinase‐activated receptors induce interleukin‐8 expression by intestinal epithelial cells through ERK/RSK90 activation and histone acetylation H Wang, F Moreau, CL Hirota, WK MacNaughton The FASEB Journal 24 (6), 1971-1980, 2010 | 52 | 2010 |
| Constitutive androstane receptor regulates the intestinal mucosal response to injury GM Hudson, KL Flannigan, SL Erickson, FA Vicentini, A Zamponi, ... British journal of pharmacology 174 (12), 1857-1871, 2017 | 42 | 2017 |
| Epidermal growth factor receptor transactivation is required for proteinase-activated receptor-2-induced COX-2 expression in intestinal epithelial cells CL Hirota, F Moreau, V Iablokov, M Dicay, B Renaux, MD Hollenberg, ... American Journal of Physiology-Gastrointestinal and Liver Physiology 303 (1 …, 2012 | 41 | 2012 |
| The EGF Receptor and HER2 Participate in TNF-α-Dependent MAPK Activation and IL-8 Secretion in Intestinal Epithelial Cells HB Jijon, A Buret, CL Hirota, MD Hollenberg, PL Beck Mediators of Inflammation 2012, 2012 | 40 | 2012 |
| M3 muscarinic receptor-deficient mice retain bethanechol-mediated intestinal ion transport and are more sensitive to colitis CL Hirota, DM McKay Canadian journal of physiology and pharmacology 84 (11), 1153-1161, 2006 | 37 | 2006 |
| Loss of Ca2+‐mediated ion transport during colitis correlates with reduced ion transport responses to a Ca2+‐activated K+ channel opener CL Hirota, DM McKay British journal of pharmacology 156 (7), 1085-1097, 2009 | 33 | 2009 |
| Prostaglandin E2 derived from cyclooxygenases 1 and 2 mediates intestinal epithelial ion transport stimulated by the activation of protease-activated receptor 2 JQ van der Merwe, CL Ohland, CL Hirota, WK MacNaughton Journal of Pharmacology and Experimental Therapeutics 329 (2), 747-752, 2009 | 23 | 2009 |
| Interferon-γ suppresses intestinal epithelial aquaporin-1 expression via Janus kinase and STAT3 activation MS Dicay, CL Hirota, NJ Ronaghan, MA Peplowski, RS Zaheer, CA Carati, ... PloS one 10 (3), e0118713, 2015 | 19 | 2015 |
| Attenuation of Clostridium difficile toxin‐induced damage to epithelial barrier by ecto‐5′‐nucleotidase (CD73) and adenosine receptor signaling L Patrick Schenck, SA Hirota, CL Hirota, P Boasquevisque, SE Tulk, Y Li, ... Neurogastroenterology & Motility 25 (6), e441-e453, 2013 | 14 | 2013 |
| E-Ring Isoprostanes Stimulate a Cl− Conductance in Airway Epithelium via Prostaglandin E2-Selective Prostanoid Receptors V Seto, C Hirota, S Hirota, LJ Janssen American journal of respiratory cell and molecular biology 38 (1), 88-94, 2008 | 13 | 2008 |
| Sa1754 Distinctive Th17 Lymphocyte Plasticity in Intestinal Lamina Propria of IBD Patients Compared With Healthy Controls J Li, A Ueno, MF Gasia, C Hirota, M Deane, R Chan, M Iacucci, G Kaplan, ... Gastroenterology 148 (4), S-323, 2015 | 4 | 2015 |
| Su1262 Downregulation of IL-17 Related Cytokines in the Second Trimester of Pregnancy in Women With IBD Supports Pregnancy Driven Immunomodulatory Effects Involving the Th17 … CH Seow, Y Leung, C Hirota, EE Afshar, G Kaplan, GK Bindra, PL Beck, ... Gastroenterology 148 (4), S-454-S-455, 2015 | 3 | 2015 |
