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Amy Hao Li
Amy Hao Li
Principal Scientist, Genentech Inc.
No verified email - Homepage
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Cited by
Cited by
Year
Structure- and function-based design of Plasmodium-selective proteasome inhibitors
H Li, AJ O’Donoghue, WA Van Der Linden, SC Xie, E Yoo, IT Foe, L Tilley, ...
Nature 530 (7589), 233-236, 2016
2412016
Directed Evolution of Ionizing Radiation Resistance in Escherichia coli
DR Harris, SV Pollock, EA Wood, RJ Goiffon, AJ Klingele, EL Cabot, ...
Journal of bacteriology 191 (16), 5240-5252, 2009
1562009
Skin commensal Malassezia globosa secreted protease attenuates Staphylococcus aureus biofilm formation
H Li, BN Goh, WK Teh, Z Jiang, JPZ Goh, A Goh, G Wu, SS Hoon, ...
Journal of Investigative Dermatology 138 (5), 1137-1145, 2018
1152018
Non-invasive imaging of idiopathic pulmonary fibrosis using cathepsin protease probes
NP Withana, X Ma, HM McGuire, M Verdoes, WA van der Linden, LO Ofori, ...
Scientific reports 6 (1), 19755, 2016
982016
Validation of the proteasome as a therapeutic target in Plasmodium using an epoxyketone inhibitor with parasite-specific toxicity
H Li, EL Ponder, M Verdoes, KH Asbjornsdottir, E Deu, LE Edgington, ...
Chemistry & biology 19 (12), 1535-1545, 2012
942012
Proteases as regulators of pathogenesis: examples from the Apicomplexa
H Li, MA Child, M Bogyo
Biochimica et Biophysica Acta (BBA)-Proteins and Proteomics 1824 (1), 177-185, 2012
802012
Design of a highly selective quenched activity-based probe and its application in dual color imaging studies of cathepsin S activity localization
K Oresic Bender, L Ofori, WA van der Linden, ED Mock, GK Datta, ...
Journal of the American Chemical Society 137 (14), 4771-4777, 2015
732015
A wireless and battery-free wound infection sensor based on DNA hydrogel
Z Xiong, S Achavananthadith, S Lian, LE Madden, ZX Ong, W Chua, ...
Science advances 7 (47), eabj1617, 2021
702021
Assessing Subunit Dependency of the Plasmodium Proteasome Using Small Molecule Inhibitors and Active Site Probes
H Li, WA Van Der Linden, M Verdoes, BI Florea, FE McAllister, ...
ACS chemical biology 9 (8), 1869-1876, 2014
542014
Identification of Potent and Selective Non-covalent Inhibitors of the Plasmodium falciparum Proteasome
H Li, C Tsu, C Blackburn, G Li, P Hales, L Dick, M Bogyo
Journal of the American Chemical Society 136 (39), 13562-13565, 2014
522014
The cryo‐EM structure of the Plasmodium falciparum 20S proteasome and its use in the fight against malaria
H Li, M Bogyo, PCA da Fonseca
The FEBS journal 283 (23), 4238-4243, 2016
342016
Templated chemistry for sequence‐specific fluorogenic detection of duplex DNA
H Li, RM Franzini, C Bruner, ET Kool
ChemBioChem 11 (15), 2132-2137, 2010
292010
Identification of Malassezia furfur Secreted Aspartyl Protease 1 (MfSAP1) and Its Role in Extracellular Matrix Degradation
SE Poh, JPZ Goh, C Fan, W Chua, SQ Gan, PLK Lim, B Sharma, ...
Frontiers in cellular and infection microbiology 10, 148, 2020
262020
Defective dissociation of a “slow” RecA mutant protein imparts an Escherichia coli growth defect
JM Cox, H Li, EA Wood, S Chitteni-Pattu, RB Inman, MM Cox
Journal of Biological Chemistry 283 (36), 24909-24921, 2008
262008
Ferrous iron-dependent drug delivery enables controlled and selective release of therapeutic agents in vivo
E Deu, IT Chen, EMW Lauterwasser, J Valderramos, H Li, LE Edgington, ...
Proceedings of the National Academy of Sciences 110 (45), 18244-18249, 2013
252013
Total Synthesis and Biological Evaluation of the Fab‐Inhibitory Antibiotic Platencin and Analogues Thereof
GYC Leung, H Li, QY Toh, AMY Ng, RJ Sum, JE Bandow, DYK Chen
European Journal of Organic Chemistry 2011 (1), 183-196, 2011
242011
Trioxolane-mediated delivery of mefloquine limits brain exposure in a mouse model of malaria
EMW Lauterwasser, SD Fontaine, H Li, J Gut, K Katneni, SA Charman, ...
ACS medicinal chemistry letters 6 (11), 1145-1149, 2015
172015
Secretory proteases of the human skin microbiome
W Chua, SE Poh, H Li
Infection and Immunity 90 (1), e00397-21, 2022
122022
The human pathobiont Malassezia furfur secreted protease Mfsap1 regulates cell dispersal and exacerbates skin inflammation
JPZ Goh, F Ruchti, SE Poh, WLC Koh, KY Tan, YT Lim, STG Thng, ...
Proceedings of the National Academy of Sciences 119 (49), e2212533119, 2022
112022
Expression of Staphylococcus aureus virulence factors in atopic dermatitis
SE Poh, WLC Koh, SYD Lim, ECE Wang, YW Yew, JEA Common, ...
JID Innovations 2 (4), 100130, 2022
82022
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