The essential kinase ATR: ensuring faithful duplication of a challenging genome JC Saldivar, D Cortez, KA Cimprich Nature Reviews Molecular Cell Biology, 2017 | 735 | 2017 |
Transcription-replication conflict orientation modulates R-loop levels and activates distinct DNA damage responses S Hamperl, MJ Bocek, JC Saldivar, T Swigut, KA Cimprich Cell 170 (4), 774-786. e19, 2017 | 573 | 2017 |
An intrinsic S/G2 checkpoint enforced by ATR JC Saldivar, S Hamperl, MJ Bocek, M Chung, TE Bass, ... Science 361 (6404), 806-810, 2018 | 275 | 2018 |
A Review of the Ecology, Genomics, and Stress Response of Listeria innocua and Listeria monocytogenes SR Milillo, EC Friedly, JC Saldivar, A Muthaiyan, C O'bryan, PG Crandall, ... Critical reviews in food science and nutrition 52 (8), 712-725, 2012 | 141 | 2012 |
Initiation of genome instability and preneoplastic processes through loss of Fhit expression JC Saldivar, S Miuma, J Bene, SA Hosseini, H Shibata, J Sun, LJ Wheeler, ... PLoS genetics 8 (11), e1003077, 2012 | 114 | 2012 |
The FHIT gene product: tumor suppressor and genome “caretaker” CE Waters, JC Saldivar, SA Hosseini, K Huebner Cellular and molecular life sciences 71, 4577-4587, 2014 | 106 | 2014 |
Fibulin-3 promotes glioma growth and resistance through a novel paracrine regulation of Notch signaling B Hu, MS Nandhu, H Sim, PA Agudelo-Garcia, JC Saldivar, CE Dolan, ... Cancer research 72 (15), 3873-3885, 2012 | 100 | 2012 |
Pathology and biology associated with the fragile FHIT gene and gene product JC Saldivar, H Shibata, K Huebner Journal of cellular biochemistry 109 (5), 858-865, 2010 | 67 | 2010 |
Common chromosome fragile sites in human and murine epithelial cells and FHIT/FRA3B loss‐induced global genome instability SA Hosseini, S Horton, JC Saldivar, S Miuma, MR Stampfer, NA Heerema, ... Genes, Chromosomes and Cancer 52 (11), 1017-1029, 2013 | 66 | 2013 |
DNA replication stress underlies renal phenotypes in CEP290-associated Joubert syndrome GG Slaats, JC Saldivar, J Bacal, MK Zeman, AC Kile, AM Hynes, ... The Journal of clinical investigation 125 (9), 3657-3666, 2015 | 61 | 2015 |
Fragile Histidine Triad (FHIT), a Novel Modifier Gene in Pulmonary Arterial Hypertension SD Prosseda, X Tian, K Kuramoto, M Boehm, D Sudheendra, K Miyagawa, ... | 49* | 2018 |
Fragile Histidine Triad (FHIT), a Novel Modifier Gene in Pulmonary Arterial Hypertension S Dannewitz Prosseda, X Tian, K Kuramoto, M Boehm, D Sudheendra, ... American journal of respiratory and critical care medicine, 2018 | 48 | 2018 |
FHIT loss-induced DNA damage creates optimal APOBEC substrates: Insights into APOBEC-mediated mutagenesis CE Waters, JC Saldivar, ZA Amin, MS Schrock, K Huebner Oncotarget 6 (5), 3409, 2015 | 40 | 2015 |
Hits, Fhits and Nits: beyond enzymatic function K Huebner, JC Saldivar, J Sun, H Shibata, T Druck Advances in enzyme regulation 51 (1), 208-217, 2011 | 38 | 2011 |
Fhit Deficiency-Induced Global Genome Instability Promotes Mutation and Clonal Expansion S Miuma, JC Saldivar, JR Karras, CE Waters, CA Paisie, Y Wang, V Jin, ... PLOS ONE 8 (11), e80730, 2013 | 37 | 2013 |
Molecular modelling of the FOXO4-TP53 interaction to design senolytic peptides for the elimination of senescent cancer cells HH Le, SS Cinaroglu, EC Manalo, A Ors, MM Gomes, BD Sahbaz, ... EBioMedicine 73, 2021 | 25 | 2021 |
Listeria monocytogenes adaptation and growth at low temperatures: mechanisms and implications for foodborne disease JC Saldivar, ML Davis, MG Johnson, SC Ricke Food and feed safety systems and analysis, 227-248, 2018 | 25 | 2018 |
Characterization of the role of Fhit in suppression of DNA damage JC Saldivar, J Bene, SA Hosseini, S Miuma, S Horton, NA Heerema, ... Advances in biological regulation 53 (1), 77-85, 2013 | 25 | 2013 |
Response of subtype‐specific human breast cancer‐derived cells to poly (ADP‐ribose) polymerase and checkpoint kinase 1 inhibition H Shibata, S Miuma, JC Saldivar, K Huebner Cancer science 102 (10), 1882-1888, 2011 | 25 | 2011 |
Eliminating hypoxic tumor cells improves response to PARP inhibitors in homologous recombination–deficient cancer models M Mehibel, Y Xu, CG Li, EJ Moon, KN Thakkar, AN Diep, RK Kim, ... The Journal of clinical investigation 131 (11), 2021 | 19 | 2021 |