Matthias Farlik

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Christoph BockCeMM Research Center for Molecular Medicine (ÖAW) & Medical University of Vienna, AustriaVerified email at bock.name
Florian HalbritterSt. Anna Children's Cancer Research Institute (CCRI), Vienna, AustriaVerified email at ccri.at
Thomas DeckerProfessor of ImmunobiologyVerified email at univie.ac.at
Johanna KlughammerBroad Institute of MIT and HarvardVerified email at broadinstitute.org
Nathan C. SheffieldAssoc. Prof. of Public Health Genomics, Biomedical Engineering, Data Science. University of VirginiaVerified email at virginia.edu
Nikolaus FortelnyUniversity of SalzburgVerified email at plus.ac.at
frederic geissmannMemorial Sloan Kettering Cancer Centre, NY, NYVerified email at mskcc.org
Ivan BallesterosCentro Nacional de Investigaciones Cardiovasculares CNICVerified email at cnic.es
Christian SchmidlLeibniz Institute for ImmunotherapyVerified email at klinik.uni-regensburg.de
Stefan KubicekCeMM Research Center for Molecular Medicine of the Austrian Academy of SciencesVerified email at cemm.oeaw.ac.at
Francesco Staehli, PhDDebiopharm International SAVerified email at global.educanet2.ch
Du Pasquier R.Professeur de neurologie, Centre Hospitalier Universitaire VaudoisVerified email at chuv.ch
Greta GuardaIstituto di Ricerca in Biomedicina (IRB), BellinzonaVerified email at irb.usi.ch
André F RendeiroCeMM Research Center for Molecular Medicine of the Austrian Academy of SciencesVerified email at cemm.oeaw.ac.at
Claus VoglUniversity of Veterinary Medicine ViennaVerified email at vetmeduni.ac.at
Joachim SchultzeUniversity of Bonn, LIMES-InstituteVerified email at uni-bonn.de
Elisa Gomez PerdigueroInstitut PasteurVerified email at pasteur.fr
Patrick GüntherMSc. Immunogenomics, LIMES institute, University of BonnVerified email at uni-bonn.de
Elvira MassLIMES Institute, University of BonnVerified email at uni-bonn.de
Christian Jacome-GalarzaInstructor in Medicine, BWH/HMSVerified email at bwh.harvard.edu

Matthias Farlik

Principal Investigator - MUW - Department of Dermatology

Verified email at meduniwien.ac.at - Homepage

Epigenetics Immunology Cancer Single cells Sequencing Technologies


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Type I interferon inhibits interleukin-1 production and inflammasome activation G Guarda, M Braun, F Staehli, A Tardivel, C Mattmann, I Förster, M Farlik, ... Immunity 34 (2), 213-223, 2011	1033	2011
Specification of tissue-resident macrophages during organogenesis E Mass, I Ballesteros, M Farlik, F Halbritter, P Günther, L Crozet, ... Science 353 (6304), aaf4238, 2016	767	2016
Single-cell DNA methylome sequencing and bioinformatic inference of epigenomic cell-state dynamics M Farlik, NC Sheffield, A Nuzzo, P Datlinger, A Schönegger, ... Cell reports 10 (8), 1386-1397, 2015	449	2015
Molecular interrogation of hypothalamic organization reveals distinct dopamine neuronal subtypes RA Romanov, A Zeisel, J Bakker, F Girach, A Hellysaz, R Tomer, A Alpar, ... Nature neuroscience 20 (2), 176-188, 2017	406	2017
Spatiotemporal structure of cell fate decisions in murine neural crest R Soldatov, M Kaucka, ME Kastriti, J Petersen, T Chontorotzea, ... Science 364 (6444), eaas9536, 2019	395	2019
Artemisinins target GABAA receptor signaling and impair α cell identity J Li, T Casteels, T Frogne, C Ingvorsen, C Honore, M Courtney, ... Cell 168 (1), 86-100. e15, 2017	382	2017
DNA methylation dynamics of human hematopoietic stem cell differentiation M Farlik, F Halbritter, F Müller, FA Choudry, P Ebert, J Klughammer, ... Cell stem cell 19 (6), 808-822, 2016	247	2016
Single‐cell transcriptomes reveal characteristic features of human pancreatic islet cell types J Li, J Klughammer, M Farlik, T Penz, A Spittler, C Barbieux, E Berishvili, ... EMBO reports 17 (2), 178-187, 2016	232	2016
Nonconventional initiation complex assembly by STAT and NF-κB transcription factors regulates nitric oxide synthase expression M Farlik, B Reutterer, C Schindler, F Greten, C Vogl, M Müller, T Decker Immunity 33 (1), 25-34, 2010	173	2010
Chromatin accessibility maps of chronic lymphocytic leukaemia identify subtype-specific epigenome signatures and transcription regulatory networks AF Rendeiro, C Schmidl, JC Strefford, R Walewska, Z Davis, M Farlik, ... Nature communications 7 (1), 11938, 2016	159	2016
SARS-CoV-2 mutations in MHC-I-restricted epitopes evade CD8⁺ T cell responses B Agerer, M Koblischke, V Gudipati, LF Montaño-Gutierrez, M Smyth, ... Science immunology 6 (57), eabg6461, 2021	153	2021
Comprehensive genome and epigenome characterization of CHO cells in response to evolutionary pressures and over time J Feichtinger, I Hernández, C Fischer, M Hanscho, N Auer, M Hackl, ... Biotechnology and bioengineering 113 (10), 2241-2253, 2016	140	2016
Multi-omics of single cells: strategies and applications C Bock, M Farlik, NC Sheffield Trends in biotechnology 34 (8), 605-608, 2016	138	2016
Distinct modes of action applied by transcription factors STAT1 and IRF1 to initiate transcription of the IFN-γ-inducible gbp2 gene K Ramsauer, M Farlik, G Zupkovitz, C Seiser, A Kröger, H Hauser, ... Proceedings of the National Academy of Sciences 104 (8), 2849-2854, 2007	137	2007
Molecular design of hypothalamus development RA Romanov, EO Tretiakov, ME Kastriti, M Zupancic, M Häring, ... Nature 582 (7811), 246-252, 2020	113	2020
Integrative proteomic profiling reveals PRC2-dependent epigenetic crosstalk maintains ground-state pluripotency G van Mierlo, RAM Dirks, L De Clerck, AB Brinkman, M Huth, SL Kloet, ... Cell stem cell 24 (1), 123-137. e8, 2019	102	2019
An ERK-dependent feedback mechanism prevents hematopoietic stem cell exhaustion C Baumgartner, S Toifl, M Farlik, F Halbritter, R Scheicher, I Fischer, ... Cell stem cell 22 (6), 879-892. e6, 2018	93	2018
Chromatin mapping and single-cell immune profiling define the temporal dynamics of ibrutinib response in CLL AF Rendeiro, T Krausgruber, N Fortelny, F Zhao, T Penz, M Farlik, ... Nature Communications 11 (1), 577, 2020	85	2020
STAT5B^N642H is a driver mutation for T cell neoplasia HTT Pham, B Maurer, M Prchal-Murphy, R Grausenburger, ... The Journal of clinical investigation 128 (1), 387-401, 2018	84	2018
Soluble TREM2 levels reflect the recruitment and expansion of TREM2+ macrophages that localize to fibrotic areas and limit NASH T Hendrikx, F Porsch, MG Kiss, D Rajcic, N Papac-Miličević, C Hoebinger, ... Journal of hepatology 77 (5), 1373-1385, 2022	70	2022

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