| A small molecule antagonist of chemokine receptors CCR1 and CCR3: potent inhibition of eosinophil function and CCR3-mediated HIV-1 entry I Sabroe, MJ Peck, BJ Van Keulen, A Jorritsma, G Simmons, PR Clapham, ... Journal of Biological Chemistry 275 (34), 25985-25992, 2000 | 272 | 2000 |
| Identification of CCR8: a human monocyte and thymus receptor for the CC chemokine I-309 HL Tiffany, LL Lautens, JL Gao, J Pease, M Locati, C Combadiere, ... The Journal of experimental medicine 186 (1), 165-170, 1997 | 266 | 1997 |
| The role of interleukin-8 and its receptors in inflammatory lung disease: implications for therapy JE Pease, I Sabroe American Journal of Respiratory Medicine 1, 19-25, 2002 | 260 | 2002 |
| IFN-λ resolves inflammation via suppression of neutrophil infiltration and IL-1β production K Blazek, HL Eames, M Weiss, AJ Byrne, D Perocheau, JE Pease, ... Journal of Experimental Medicine 212 (6), 845-853, 2015 | 240 | 2015 |
| Differential regulation of eosinophil chemokine signaling via CCR3 and non-CCR3 pathways I Sabroe, A Hartnell, LA Jopling, S Bel, PD Ponath, JE Pease, PD Collins, ... The Journal of Immunology 162 (5), 2946-2955, 1999 | 219 | 1999 |
| CCR3 functional responses are regulated by both CXCR3 and its ligands CXCL9, CXCL10 and CXCL11 G Xanthou, CE Duchesnes, TJ Williams, JE Pease European journal of immunology 33 (8), 2241-2250, 2003 | 163 | 2003 |
| Pulmonary epithelial cell-derived cytokine TGF-β1 is a critical cofactor for enhanced innate lymphoid cell function L Denney, AJ Byrne, TJ Shea, JS Buckley, JE Pease, GMF Herledan, ... Immunity 43 (5), 945-958, 2015 | 162 | 2015 |
| The N-terminal extracellular segments of the chemokine receptors CCR1 and CCR3 are determinants for MIP-1α and eotaxin binding, respectively, but a second domain is essential … JE Pease, J Wang, PD Ponath, PM Murphy Journal of Biological Chemistry 273 (32), 19972-19976, 1998 | 153 | 1998 |
| Challenges and opportunities in the clinical development of STING agonists for cancer immunotherapy L Motedayen Aval, JE Pease, R Sharma, DJ Pinato Journal of clinical medicine 9 (10), 3323, 2020 | 152 | 2020 |
| The chemokine receptor CXCR3 is degraded following internalization and is replenished at the cell surface by de novo synthesis of receptor A Meiser, A Mueller, EL Wise, EM McDonagh, SJ Petit, N Saran, PC Clark, ... The Journal of Immunology 180 (10), 6713-6724, 2008 | 152 | 2008 |
| Molecular cloning of leukotactin-1: a novel human beta-chemokine, a chemoattractant for neutrophils, monocytes, and lymphocytes, and a potent agonist at CC chemokine receptors … BS Youn, SM Zhang, EK Lee, DH Park, HE Broxmeyer, PM Murphy, ... Journal of immunology (Baltimore, Md.: 1950) 159 (11), 5201-5205, 1997 | 152 | 1997 |
| Chemokines and their receptors in allergic disease JE Pease, TJ Williams Journal of allergy and clinical immunology 118 (2), 305-318, 2006 | 146 | 2006 |
| Eotaxin and asthma JE Pease, TJ Williams Current opinion in pharmacology 1 (3), 248-253, 2001 | 142 | 2001 |
| IRF5 controls both acute and chronic inflammation M Weiss, AJ Byrne, K Blazek, DG Saliba, JE Pease, D Perocheau, ... Proceedings of the National Academy of Sciences 112 (35), 11001-11006, 2015 | 139 | 2015 |
| Chemokine receptor antagonists: Part 1 JE Pease, R Horuk Expert opinion on therapeutic patents 19 (1), 39-58, 2009 | 136 | 2009 |
| CXCL4-induced migration of activated T lymphocytes is mediated by the chemokine receptor CXCR3 A Mueller, A Meiser, EM McDonagh, JM Fox, SJ Petit, G Xanthou, ... Journal of Leucocyte Biology 83 (4), 875-882, 2008 | 133 | 2008 |
| Asthma, allergy and chemokines JE Pease Current drug targets 7 (1), 3-12, 2006 | 132 | 2006 |
| Predictions of CCR1 chemokine receptor structure and BX 471 antagonist binding followed by experimental validation N Vaidehi, S Schlyer, RJ Trabanino, WB Floriano, R Abrol, S Sharma, ... Journal of Biological Chemistry 281 (37), 27613-27620, 2006 | 127 | 2006 |
| 11-Dehydro-thromboxane B2, a stable thromboxane metabolite, is a full agonist of chemoattractant receptor-homologous molecule expressed on TH2 cells (CRTH2) in human … E Böhm, GJ Sturm, I Weiglhofer, H Sandig, M Shichijo, A McNamee, ... Journal of Biological Chemistry 279 (9), 7663-7670, 2004 | 127 | 2004 |
| The CXC Chemokine MIG/CXCL9 Is Important in Innate Immunity against Streptococcus pyogenes A Egesten, M Eliasson, HM Johansson, AI Olin, M Mörgelin, A Mueller, ... The Journal of infectious diseases 195 (5), 684-693, 2007 | 123 | 2007 |
Timothy John WilliamsImperial College LondonVerifierad e-postadress på imperial.ac.uk
