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Ophelia Venturelli
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Deciphering microbial interactions in synthetic human gut microbiome communities
OS Venturelli, AV Carr, G Fisher, RH Hsu, R Lau, BP Bowen, S Hromada, ...
Molecular systems biology 14 (6), e8157, 2018
4082018
Common principles and best practices for engineering microbiomes
CE Lawson, WR Harcombe, R Hatzenpichler, SR Lindemann, FE Löffler, ...
Nature Reviews Microbiology 17 (12), 725-741, 2019
3882019
The pro-longevity gene FoxO3 is a direct target of the p53 tumor suppressor
VM Renault, PU Thekkat, KL Hoang, JL White, CA Brady, ...
Oncogene 30 (29), 3207-3221, 2011
1462011
Evolution favors protein mutational robustness in sufficiently large populations
JD Bloom, Z Lu, D Chen, A Raval, OS Venturelli, FH Arnold
BMC biology 5, 1-21, 2007
1272007
Population diversification in a yeast metabolic program promotes anticipation of environmental shifts
OS Venturelli, I Zuleta, RM Murray, H El-Samad
PLoS biology 13 (1), e1002042, 2015
1192015
Design of synthetic human gut microbiome assembly and butyrate production
RL Clark, BM Connors, DM Stevenson, SE Hromada, JJ Hamilton, ...
Nature communications 12 (1), 3254, 2021
1082021
Microbial Interaction Network Inference in Microfluidic Droplets
RH Hsu, RL Clark, JW Tan, JC Ahn, S Gupta, PA Romero, OS Venturelli
Cell systems 9 (3), 229-242. e4, 2019
972019
EcoFABs: advancing microbiome science through standardized fabricated ecosystems
K Zengler, K Hofmockel, NS Baliga, SW Behie, HC Bernstein, JB Brown, ...
Nature methods 16 (7), 567-571, 2019
962019
Synergistic dual positive feedback loops established by molecular sequestration generate robust bimodal response
OS Venturelli, H El-Samad, RM Murray
Proceedings of the National Academy of Sciences 109 (48), E3324-E3333, 2012
882012
Investigating the dynamics of microbial consortia in spatially structured environments
S Gupta, TD Ross, MM Gomez, JL Grant, PA Romero, OS Venturelli
Nature communications 11 (1), 2418, 2020
732020
Programming mRNA decay to modulate synthetic circuit resource allocation
OS Venturelli, M Tei, S Bauer, LJG Chan, CJ Petzold, AP Arkin
Nature Communications 8 (1), 15128, 2017
522017
Polysaccharide utilization loci in Bacteroides determine population fitness and community-level interactions
J Feng, Y Qian, Z Zhou, S Ertmer, EI Vivas, F Lan, JJ Hamilton, FE Rey, ...
Cell host & microbe 30 (2), 200-215. e12, 2022
492022
Towards engineering biological systems in a broader context
OS Venturelli, RG Egbert, AP Arkin
Journal of molecular biology 428 (5), 928-944, 2016
412016
Negative interactions determine Clostridioides difficile growth in synthetic human gut communities
S Hromada, Y Qian, TB Jacobson, RL Clark, L Watson, N Safdar, ...
Molecular systems biology 17 (10), e10355, 2021
37*2021
Towards a deeper understanding of microbial communities: integrating experimental data with dynamic models
Y Qian, F Lan, OS Venturelli
Current opinion in microbiology 62, 84-92, 2021
352021
Recurrent neural networks enable design of multifunctional synthetic human gut microbiome dynamics
M Baranwal, RL Clark, J Thompson, Z Sun, AO Hero, O Venturelli
Elife, 0
33*
Integrating systems and synthetic biology to understand and engineer microbiomes
PA Leggieri, Y Liu, M Hayes, B Connors, S Seppälä, MA O'Malley, ...
Annual Review of Biomedical Engineering 23, 169-201, 2021
312021
Understanding and engineering distributed biochemical pathways in microbial communities
X Cao, JJ Hamilton, OS Venturelli
Biochemistry 58 (2), 94-107, 2018
302018
Scalable nonlinear programming framework for parameter estimation in dynamic biological system models
S Shin, OS Venturelli, VM Zavala
PLoS computational biology 15 (3), e1006828, 2019
192019
Carbohydrate complexity limits microbial growth and reduces the sensitivity of human gut communities to perturbations
E Ostrem Loss, J Thompson, PLK Cheung, Y Qian, OS Venturelli
Nature ecology & evolution 7 (1), 127-142, 2023
112023
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Articles 1–20