MAP kinase signalling pathways in cancer AS Dhillon, S Hagan, O Rath, W Kolch Oncogene 26 (22), 3279-3290, 2007 | 3680 | 2007 |
Meaningful relationships: the regulation of the Ras/Raf/MEK/ERK pathway by protein interactions W Kolch Biochemical Journal 351 (2), 289-305, 2000 | 2239 | 2000 |
Protein kinase Cα activates RAF-1 by direct phosphorylation W Kolch, G Heidecker, G Kochs, R Hummel, H Vahidi, H Mischak, ... Nature 364 (6434), 249-252, 1993 | 1664 | 1993 |
Coordinating ERK/MAPK signalling through scaffolds and inhibitors W Kolch Nature reviews Molecular cell biology 6 (11), 827-837, 2005 | 1391 | 2005 |
Suppression of Raf-1 kinase activity and MAP kinase signalling by RKIP K Yeung, T Seitz, S Li, P Janosch, B McFerran, C Kaiser, F Fee, ... Nature 401 (6749), 173-177, 1999 | 1070 | 1999 |
Signalling ballet in space and time BN Kholodenko, JF Hancock, W Kolch Nature reviews Molecular cell biology 11 (6), 414-426, 2010 | 735 | 2010 |
Overexpression of protein kinase C-delta and-epsilon in NIH 3T3 cells induces opposite effects on growth, morphology, anchorage dependence, and tumorigenicity. H Mischak, JA Goodnight, W Kolch, G Martiny-Baron, C Schaechtle, ... Journal of Biological Chemistry 268 (9), 6090-6096, 1993 | 708 | 1993 |
Mutant p53 potentiates protein kinase C induction of vascular endothelial growth factor expression A Kieser, HA Weich, G Brandner, D Marmé, W Kolch Oncogene 9 (3), 963-970, 1994 | 697 | 1994 |
Raf-1 protein kinase is required for growth of induced NIH/3T3 cells W Kolch, G Heidecker, P Lloyd, UR Rapp Nature 349 (6308), 426-428, 1991 | 658 | 1991 |
Targeting MAPK signaling in cancer: mechanisms of drug resistance and sensitivity S Lee, J Rauch, W Kolch International journal of molecular sciences 21 (3), 1102, 2020 | 650 | 2020 |
The Parkinson disease causing LRRK2 mutation I2020T is associated with increased kinase activity CJ Gloeckner, N Kinkl, A Schumacher, RJ Braun, E O'Neill, T Meitinger, ... Human molecular genetics 15 (2), 223-232, 2006 | 580 | 2006 |
Naturally occurring human urinary peptides for use in diagnosis of chronic kidney disease DM Good, P Zürbig, A Argiles, HW Bauer, G Behrens, JJ Coon, M Dakna, ... Molecular & cellular proteomics 9 (11), 2424-2437, 2010 | 570 | 2010 |
Computational modelling of the receptor-tyrosine-kinase-activated MAPK pathway RJ Orton, OE Sturm, V Vyshemirsky, M Calder, DR Gilbert, W Kolch Biochemical Journal 392 (2), 249-261, 2005 | 546 | 2005 |
Regulation and role of Raf-1/B-Raf heterodimerization LK Rushworth, AD Hindley, E O'Neill, W Kolch Molecular and cellular biology, 2006 | 529 | 2006 |
Mechanism of suppression of the Raf/MEK/extracellular signal-regulated kinase pathway by the raf kinase inhibitor protein K Yeung, P Janosch, B McFerran, DW Rose, H Mischak, JM Sedivy, ... Molecular and cellular biology 20 (9), 3079-3085, 2000 | 507 | 2000 |
Raf kinase inhibitor protein interacts with NF-κB-inducing kinase and TAK1 and inhibits NF-κB activation KC Yeung, DW Rose, AS Dhillon, D Yaros, M Gustafsson, D Chatterjee, ... Molecular and cellular biology 21 (21), 7207-7217, 2001 | 506 | 2001 |
Identification of the mechanisms regulating the differential activation of the mapk cascade by epidermal growth factor and nerve growth factor in PC12 cells S Kao, RK Jaiswal, W Kolch, GE Landreth Journal of Biological Chemistry 276 (21), 18169-18177, 2001 | 488 | 2001 |
Raf family kinases: old dogs have learned new tricks D Matallanas, M Birtwistle, D Romano, A Zebisch, J Rauch, ... Genes & cancer 2 (3), 232-260, 2011 | 476 | 2011 |
RASSF1A elicits apoptosis through an MST2 pathway directing proapoptotic transcription by the p73 tumor suppressor protein D Matallanas, D Romano, K Yee, K Meissl, L Kucerova, D Piazzolla, ... Molecular cell 27 (6), 962-975, 2007 | 453 | 2007 |
Epstein–Barr virus latent membrane protein‐1 triggers AP‐1 activity via the c‐Jun N‐terminal kinase cascade A Kieser, E Kilger, O Gires, M Ueffing, W Kolch, W Hammerschmidt The EMBO journal, 1997 | 415 | 1997 |