| Cytochrome P450 2E1 and 2A6 enzymes as major catalysts for metabolic activation of N-nitrosodialkylamines and tobacco-related nitrosamines in human liver … H Yamazaki, Y Inui, CH Yun, FP Guengerich, T Shimada Carcinogenesis 13 (10), 1789-1794, 1992 | 505 | 1992 |
| Cytochrome P-450 3A enzymes are responsible for biotransformation of FK506 and rapamycin in man and rat. M Sattler, FP Guengerich, CH Yun, U Christians, KFR Sewing Drug metabolism and disposition 20 (5), 753-761, 1992 | 500 | 1992 |
| Purification and characterization of human liver microsomal cytochrome P-450 2A6. CH Yun, T Shimada, FP Guengerich Molecular pharmacology 40 (5), 679-685, 1991 | 361 | 1991 |
| Characterization of human lung microsomal cytochrome P-450 1A1 and its role in the oxidation of chemical carcinogens. T Shimada, CH Yun, H Yamazaki, JC Gautier, PH Beaune, ... Molecular pharmacology 41 (5), 856-864, 1992 | 323 | 1992 |
| Oxidation of the antihistaminic drug terfenadine in human liver microsomes. Role of cytochrome P-450 3A (4) in N-dealkylation and C-hydroxylation. CH Yun, RA Okerholm, FP Guengerich Drug metabolism and Disposition 21 (3), 403-409, 1993 | 306 | 1993 |
| Evidence for a 1-electron oxidation mechanism in N-dealkylation of N, N-dialkylanilines by cytochrome P450 2B1: kinetic hydrogen isotope effects, linear free energy … FP Guengerich, CH Yun, TL Macdonald Journal of Biological Chemistry 271 (44), 27321-27329, 1996 | 187 | 1996 |
| Rate-determining steps in phenacetin oxidations by human cytochrome P450 1A2 and selected mutants CH Yun, GP Miller, FP Guengerich Biochemistry 39 (37), 11319-11329, 2000 | 170 | 2000 |
| Separation of human liver microsomal tolbutamide hydroxylase and (S)-mephenytoin 4'-hydroxylase cytochrome P-450 enzymes. PK Srivastava, CH Yun, PH Beaune, C Ged, FP Guengerich Molecular pharmacology 40 (1), 69-79, 1991 | 144 | 1991 |
| Identification of the pharmacogenetic determinants of alfentanil metabolism: cytochrome P-450 3A4. An explanation of the variable elimination clearance. CH Yun, M Wood, AJ Wood, FP Guengerich Anesthesiology 77 (3), 467-474, 1992 | 142 | 1992 |
| Roles of Human Liver Cytochrome P4502C and 3A Enzymes in the 3-Hydroxylation of Benzo(a)pyrene CH Yun, T Shimada, FP Guengerich Cancer Research 52 (7), 1868-1874, 1992 | 132 | 1992 |
| The bacterial P450 BM3: a prototype for a biocatalyst with human P450 activities CH Yun, KH Kim, DH Kim, HC Jung, JG Pan Trends in biotechnology 25 (7), 289-298, 2007 | 123 | 2007 |
| Non-specific inhibition of cytochrome P450 activities by chlorophyllin in human and rat liver microsomes CH Yun, HG Jeong, JW Jhoun, FP Guengerich Carcinogenesis 16 (6), 1437-1440, 1995 | 114 | 1995 |
| Cofactor‐free light‐driven whole‐cell cytochrome P450 catalysis JH Park, SH Lee, GS Cha, DS Choi, DH Nam, JH Lee, JK Lee, CH Yun, ... Angewandte Chemie 127 (3), 983-987, 2015 | 112 | 2015 |
| Oxidation of the angiotensin II receptor antagonist losartan (DuP 753) in human liver microsomes. Role of cytochrome P4503A (4) in formation of the active metabolite EXP3174. CH Yun, HS Lee, H Lee, JK Rho, HG Jeong, FP Guengerich Drug metabolism and disposition 23 (2), 285-289, 1995 | 112 | 1995 |
| Functional expression of human cytochrome P450 enzymes in Escherichia coli CH Yun, SK Yim, DH Kim, T Ahn Current drug metabolism 7 (4), 411-429, 2006 | 109 | 2006 |
| Interactions of ingested food, beverage, and tobacco components involving human cytochrome P4501A2, 2A6, 2E1, and 3A4 enzymes. FP Guengerich, T Shimada, CH Yun, H Yamazaki, KD Raney, R Thier, ... Environmental health perspectives 102 (suppl 9), 49-53, 1994 | 107 | 1994 |
| Generation of the human metabolite piceatannol from the anticancer-preventive agent resveratrol by bacterial cytochrome P450 BM3 DH Kim, T Ahn, HC Jung, JG Pan, CH Yun Drug metabolism and disposition 37 (5), 932-936, 2009 | 103 | 2009 |
| Kinetic analysis of oxidation of coumarins by human cytochrome P450 2A6 CH Yun, KH Kim, MW Calcutt, FP Guengerich Journal of Biological Chemistry 280 (13), 12279-12291, 2005 | 100 | 2005 |
| ROS inhibit the expression of testicular steroidogenic enzyme genes via the suppression of Nur77 transactivation SY Lee, EY Gong, CY Hong, KH Kim, JS Han, JC Ryu, HZ Chae, CH Yun, ... Free Radical Biology and Medicine 47 (11), 1591-1600, 2009 | 92 | 2009 |
| Interaction of human thiol-specific antioxidant protein 1 with erythrocyte plasma membrane MK Cha, CH Yun, IH Kim Biochemistry 39 (23), 6944-6950, 2000 | 91 | 2000 |
Fred GuengerichProfessor of Biochemistry, Vanderbilt UniversityVerified email at vanderbilt.edu
