Daniel J. Balick
Daniel J. Balick
Instructor at Harvard Medical School and Brigham and Women's Hospital
Verifierad e-postadress på bwh.harvard.edu
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Distribution of fixed beneficial mutations and the rate of adaptation in asexual populations
BH Good, IM Rouzine, DJ Balick, O Hallatschek, MM Desai
Proceedings of the National Academy of Sciences 109 (13), 4950-4955, 2012
1882012
No evidence that selection has been less effective at removing deleterious mutations in Europeans than in Africans
R Do, D Balick, H Li, I Adzhubei, S Sunyaev, D Reich
Nature genetics 47 (2), 126-131, 2015
1532015
Estimating the selective effects of heterozygous protein-truncating variants from human exome data
CA Cassa, D Weghorn, DJ Balick, DM Jordan, D Nusinow, KE Samocha, ...
Nature genetics 49 (5), 806-810, 2017
892017
Dynamic mutation–selection balance as an evolutionary attractor
S Goyal, DJ Balick, ER Jerison, RA Neher, BI Shraiman, MM Desai
Genetics 191 (4), 1309-1319, 2012
862012
Dominance of deleterious alleles controls the response to a population bottleneck
DJ Balick, R Do, CA Cassa, D Reich, SR Sunyaev
PLoS genetics 11 (8), e1005436, 2015
662015
Quantification of frequency-dependent genetic architectures in 25 UK Biobank traits reveals action of negative selection
AP Schoech, DM Jordan, PR Loh, S Gazal, LJ O’Connor, DJ Balick, ...
Nature communications 10 (1), 1-10, 2019
582019
Quantification of frequency-dependent genetic architectures and action of negative selection in 25 UK Biobank traits
AP Schoech, D Jordan, PR Loh, S Gazal, L O’Connor, DJ Balick, ...
BioRxiv, 188086, 2017
142017
Applicability of the Mutation–Selection Balance Model to Population Genetics of Heterozygous Protein-Truncating Variants in Humans
D Weghorn, DJ Balick, C Cassa, JA Kosmicki, MJ Daly, DR Beier, ...
Molecular biology and evolution 36 (8), 1701-1710, 2019
102019
Quantification of frequency-dependent genetic architectures and action of negative selection in 25 UK Biobank traits. bioRxiv
A Schoech, D Jordan, PR Loh, S Gazal, L O’Connor, DJ Balick, ...
September, 2017
72017
Response to a population bottleneck can be used to infer recessive selection
DJ Balick, R Do, D Reich, SR Sunyaev
arXiv preprint arXiv:1312.3028, 2013
72013
The rate of adaptation and the distribution of fixed beneficial mutations in asexual populations
BH Good, IM Rouzine, DJ Balick, O Hallatschek, MM Desai
Proc. Natl. Acad. Sci. USA 109, 4950-4955, 2012
62012
No evidence that natural selection has been less effective at removing deleterious mutations in Europeans than in West Africans
R Do, D Balick, H Li, I Adzhubei, S Sunyaev, D Reich
arXiv preprint arXiv:1402.4896, 2014
52014
Rare beneficial mutations can halt Muller's ratchet
S Goyal, DJ Balick, ER Jerison, RA Neher, BI Shraiman, MM Desai
arXiv preprint arXiv:1110.2939, 2011
42011
Reply to ‘Selective effects of heterozygous protein-truncating variants’
CA Cassa, D Weghorn, DJ Balick, DM Jordan, D Nusinow, KE Samocha, ...
Nature genetics 51 (1), 3-4, 2019
32019
Rare beneficial mutations can halt Muller's ratchet
D Balick, S Goyal, E Jerison, R Neher, B Shraiman, M Desai
APS March Meeting Abstracts 2012, B51. 005, 2012
22012
Purifying selection on noncoding deletions of human regulatory loci detected using their cellular pleiotropy
DW Radke, JH Sul, DJ Balick, S Akle, RC Green, SR Sunyaev, ...
Genome Research 31 (6), 935-946, 2021
2021
Probing the aggregated effects of purifying selection per individual on 1,380 medical phenotypes in the UK biobank
HMT Vy, DM Jordan, DJ Balick, R Do
PLoS genetics 17 (1), e1009337, 2021
2021
Overcoming constraints on the detection of recessive selection in human genes from population frequency data
DJ Balick, DM Jordan, S Sunyaev, R Do
bioRxiv, 2021
2021
Recessive Selection in Complex Disease: Implications for Variant Discovery and Disease Architecture
D Jordan, D Balick, S Sunyaev, R Do
GENETIC EPIDEMIOLOGY 40 (7), 612-612, 2016
2016
Inferring the Mode of Selection from the Transient Response to Demographic Perturbations
D Balick, R Do, D Reich, S Sunyaev
APS March Meeting Abstracts 2014, D10. 003, 2014
2014
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Artiklar 1–20