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Christopher D. Fage
Christopher D. Fage
Verifierad e-postadress på cmd.ox.ac.uk
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Insights into the unique phosphorylation of the lasso peptide paeninodin
S Zhu, JD Hegemann, CD Fage, M Zimmermann, X Xie, U Linne, ...
Journal of Biological Chemistry 291 (26), 13662-13678, 2016
1242016
Catalytic mechanism and allosteric regulation of an oligomeric (p) ppGpp synthetase by an alarmone
W Steinchen, JS Schuhmacher, F Altegoer, CD Fage, V Srinivasan, ...
Proceedings of the National Academy of Sciences 112 (43), 13348-13353, 2015
1232015
The structure of SpnF, a standalone enzyme that catalyzes [4+ 2] cycloaddition
CD Fage, EA Isiorho, Y Liu, DT Wagner, H Liu, AT Keatinge-Clay
Nature chemical biology 11 (4), 256-258, 2015
1142015
Structural and mutational analysis of the nonribosomal peptide synthetase heterocyclization domain provides insight into catalysis
K Bloudoff, CD Fage, MA Marahiel, TM Schmeing
Proceedings of the National Academy of Sciences 114 (1), 95-100, 2017
762017
The B1 protein guides the biosynthesis of a lasso peptide
S Zhu, CD Fage, JD Hegemann, A Mielcarek, D Yan, U Linne, ...
Scientific reports 6 (1), 1-12, 2016
672016
Antimicrobial Peptide Resistance of Vibrio cholerae Results from an LPS Modification Pathway Related to Nonribosomal Peptide Synthetases
JC Henderson, CD Fage, JR Cannon, JS Brodbelt, AT Keatinge-Clay, ...
ACS chemical biology 9 (10), 2382-2392, 2014
642014
The missing linker: a dimerization motif located within polyketide synthase modules
J Zheng, CD Fage, B Demeler, DW Hoffman, AT Keatinge-Clay
ACS chemical biology 8 (6), 1263-1270, 2013
502013
Crystallographic study of the phosphoethanolamine transferase EptC required for polymyxin resistance and motility in Campylobacter jejuni
CD Fage, DB Brown, JM Boll, AT Keatinge-Clay, MS Trent
Acta Crystallographica Section D: Biological Crystallography 70 (10), 2730-2739, 2014
462014
The ring residue proline 8 is crucial for the thermal stability of the lasso peptide caulosegnin II
JD Hegemann, CD Fage, S Zhu, K Harms, FS Di Leva, E Novellino, ...
Molecular BioSystems 12 (4), 1106-1109, 2016
402016
Structure and mechanism of the sphingopyxin I lasso peptide isopeptidase
CD Fage, JD Hegemann, AJ Nebel, RM Steinbach, S Zhu, U Linne, ...
Angewandte Chemie International Edition 55 (41), 12717-12721, 2016
302016
The Kalimantacin Polyketide Antibiotics Inhibit Fatty Acid Biosynthesis in Staphylococcus aureus by Targeting the Enoyl‐Acyl Carrier Protein Binding Site of FabI
CD Fage, T Lathouwers, M Vanmeert, LJ Gao, K Vrancken, EM Lammens, ...
Angewandte Chemie International Edition 59 (26), 10549-10556, 2020
272020
General rules of fragmentation evidencing lasso structures in CID and ETD
KJD Fouque, H Lavanant, S Zirah, JD Hegemann, CD Fage, MA Marahiel, ...
Analyst 143 (5), 1157-1170, 2018
272018
Dual substrate‐controlled kinase activity leads to polyphosphorylated lasso peptides
S Zhu, CD Fage, JD Hegemann, D Yan, MA Marahiel
FEBS letters 590 (19), 3323-3334, 2016
252016
Crystal Structure of Bacillus subtilis Cysteine Desulfurase SufS and Its Dynamic Interaction with Frataxin and Scaffold Protein SufU
B Blauenburg, A Mielcarek, F Altegoer, CD Fage, U Linne, G Bange, ...
PLoS One 11 (7), e0158749, 2016
252016
Understanding the early stages of peptide formation during the biosynthesis of teicoplanin and related glycopeptide antibiotics
M Kaniusaite, J Tailhades, T Kittilä, CD Fage, RJA Goode, ...
The FEBS Journal 288 (2), 507-529, 2021
172021
Communication breakdown: dissecting the COM interfaces between the subunits of nonribosomal peptide synthetases
CD Fage, S Kosol, M Jenner, C Oster, A Gallo, M Kaniusaite, R Steinbach, ...
ACS Catalysis 11 (17), 10802-10813, 2021
162021
Simple inhibitors of histone deacetylase activity that combine features of short-chain fatty acid and hydroxamic acid inhibitors
JL Tischler, B Abuaita, SC Cuthpert, C Fage, K Murphy, A Saxe, EB Furr, ...
Journal of enzyme inhibition and medicinal chemistry 23 (4), 549-555, 2008
152008
Coenzyme A-free activity, crystal structure, and rational engineering of a promiscuous β-ketoacyl thiolase from Ralstonia eutropha
CD Fage, JL Meinke, AT Keatinge-Clay
Journal of Molecular Catalysis B: Enzymatic 121, 113-121, 2015
142015
Recent advances and perspectives on expanding the chemical diversity of lasso peptides
M Wang, CD Fage, Y He, J Mi, Y Yang, F Li, X An, H Fan, L Song, S Zhu, ...
Frontiers in Bioengineering and Biotechnology 9, 741364, 2021
82021
Discovery and characterization of rubrinodin provide clues into the evolution of lasso peptides
H Xiu, M Wang, CD Fage, Y He, X Niu, M Han, F Li, X An, H Fan, L Song, ...
Biochemistry 61 (7), 595-607, 2022
72022
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Artiklar 1–20