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Wendy Keung
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Targeting fatty acid and carbohydrate oxidation—a novel therapeutic intervention in the ischemic and failing heart
JS Jaswal, W Keung, W Wang, JR Ussher, GD Lopaschuk
Biochimica et Biophysica Acta (BBA)-Molecular Cell Research 1813 (7), 1333-1350, 2011
4682011
Inhibition of de novo ceramide synthesis reverses diet-induced insulin resistance and enhances whole-body oxygen consumption
JR Ussher, TR Koves, VJJ Cadete, L Zhang, JS Jaswal, SJ Swyrd, ...
Diabetes 59 (10), 2453-2464, 2010
3992010
Role of fatty acid uptake and fatty acid β-oxidation in mediating insulin resistance in heart and skeletal muscle
L Zhang, W Keung, V Samokhvalov, W Wang, GD Lopaschuk
Biochimica et Biophysica Acta (BBA)-Molecular and Cell Biology of Lipids …, 2010
3482010
Leptin activates hypothalamic acetyl-CoA carboxylase to inhibit food intake
S Gao, KP Kinzig, S Aja, KA Scott, W Keung, S Kelly, K Strynadka, ...
Proceedings of the National Academy of Sciences 104 (44), 17358-17363, 2007
2592007
Mouse models of atherosclerosis: a historical perspective and recent advances
YT Lee, HY Lin, YWF Chan, KHC Li, OTL To, BP Yan, T Liu, G Li, ...
Lipids in health and disease 16, 1-11, 2017
2102017
Aptamer-based microfluidic electrochemical biosensor for monitoring cell-secreted trace cardiac biomarkers
SR Shin, YS Zhang, DJ Kim, A Manbohi, H Avci, A Silvestri, J Aleman, ...
Analytical chemistry 88 (20), 10019-10027, 2016
2042016
Stimulation of glucose oxidation protects against acute myocardial infarction and reperfusion injury
JR Ussher, W Wang, M Gandhi, W Keung, V Samokhvalov, T Oka, ...
Cardiovascular research 94 (2), 359-369, 2012
1942012
Bioengineering an electro-mechanically functional miniature ventricular heart chamber from human pluripotent stem cells
RA Li, W Keung, TJ Cashman, PC Backeris, BV Johnson, ES Bardot, ...
Biomaterials 163, 116-127, 2018
1512018
Inhibition of carnitine palmitoyltransferase-1 activity alleviates insulin resistance in diet-induced obese mice
W Keung, JR Ussher, JS Jaswal, M Raubenheimer, VHM Lam, CS Wagg, ...
Diabetes 62 (3), 711-720, 2013
1432013
A simple, cost-effective but highly efficient system for deriving ventricular cardiomyocytes from human pluripotent stem cells
Z Weng, CW Kong, L Ren, I Karakikes, L Geng, J He, MZY Chow, CF Mok, ...
Stem cells and development 23 (14), 1704-1716, 2014
1212014
Developmental cues for the maturation of metabolic, electrophysiological and calcium handling properties of human pluripotent stem cell-derived cardiomyocytes
W Keung, KR Boheler, RA Li
Stem cell research & therapy 5, 1-11, 2014
1052014
Electrophysiological mechanisms of long and short QT syndromes
G Tse, YWF Chan, W Keung, BP Yan
IJC Heart & Vasculature 14, 8-13, 2017
942017
A heart‐breast cancer‐on‐a‐chip platform for disease modeling and monitoring of cardiotoxicity induced by cancer chemotherapy
J Lee, S Mehrotra, E Zare‐Eelanjegh, RO Rodrigues, A Akbarinejad, ...
Small 17 (15), 2004258, 2021
872021
Effect of engineered anisotropy on the susceptibility of human pluripotent stem cell-derived ventricular cardiomyocytes to arrhythmias
J Wang, A Chen, DK Lieu, I Karakikes, G Chen, W Keung, CW Chan, ...
Biomaterials 34 (35), 8878-8886, 2013
832013
Proteomic analysis of human pluripotent stem Cell–Derived, fetal, and adult ventricular cardiomyocytes reveals pathways crucial for cardiac metabolism and maturation
E Poon, W Keung, Y Liang, R Ramalingam, B Yan, S Zhang, A Chopra, ...
Circulation: Cardiovascular Genetics 8 (3), 427-436, 2015
632015
Inhibition of serine palmitoyl transferase I reduces cardiac ceramide levels and increases glycolysis rates following diet-induced insulin resistance
JR Ussher, CDL Folmes, W Keung, N Fillmore, JS Jaswal, VJ Cadete, ...
PLoS One 7 (5), e37703, 2012
592012
Electrophysiological mechanisms of Brugada syndrome: insights from pre-clinical and clinical studies
G Tse, T Liu, KHC Li, V Laxton, YWF Chan, W Keung, RA Li, BP Yan
Frontiers in Physiology 7, 467, 2016
582016
Human ISL1+ ventricular progenitors self-assemble into an in vivo functional heart patch and preserve cardiac function post infarction
KS Foo, ML Lehtinen, CY Leung, X Lian, J Xu, W Keung, L Geng, ...
Molecular Therapy 26 (7), 1644-1659, 2018
562018
Nonmulberry silk based ink for fabricating mechanically robust cardiac patches and endothelialized myocardium‐on‐a‐chip application
S Mehrotra, BAG de Melo, M Hirano, W Keung, RA Li, BB Mandal, ...
Advanced functional materials 30 (12), 1907436, 2020
542020
Machine learning of human pluripotent stem cell-derived engineered cardiac tissue contractility for automated drug classification
EK Lee, DD Tran, W Keung, P Chan, G Wong, CW Chan, KD Costa, RA Li, ...
Stem Cell Reports 9 (5), 1560-1572, 2017
542017
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