Dr. Istvan Horvath
Dr. Istvan Horvath
Researcher, Division Of Chemical Biology, Chalmers University of Technology
Verified email at chalmers.se
TitleCited byYear
TPPP/p25 promotes tubulin assemblies and blocks mitotic spindle formation
L Tirián, E Hlavanda, J Oláh, I Horváth, F Orosz, B Szabó, J Kovács, ...
Proceedings of the National Academy of Sciences 100 (24), 13976-13981, 2003
1022003
Interactions of pathological hallmark proteins tubulin polymerization promoting protein/p25, β-amyloid, and α-synuclein
J Oláh, O Vincze, D Virók, D Simon, Z Bozsó, N Tőkési, I Horváth, ...
Journal of Biological Chemistry 286 (39), 34088-34100, 2011
962011
Mechanisms of protein oligomerization: inhibitor of functional amyloids templates α-synuclein fibrillation
I Horvath, CF Weise, EK Andersson, E Chorell, M Sellstedt, C Bengtsson, ...
Journal of the American Chemical Society 134 (7), 3439-3444, 2012
892012
TPPP/p25 promotes tubulin acetylation by inhibiting histone deacetylase 6
N Tőkési, A Lehotzky, I Horváth, B Szabó, J Oláh, P Lau, J Ovádi
Journal of Biological Chemistry 285 (23), 17896-17906, 2010
822010
Tubulin polymerization promoting proteins (TPPPs): members of a new family with distinct structures and functions
O Vincze, N Tökési, J Oláh, E Hlavanda, Á Zotter, I Horváth, A Lehotzky, ...
Biochemistry 45 (46), 13818-13826, 2006
642006
Interactions of enolase isoforms with tubulin and microtubules during myogenesis
A Keller, J Peltzer, G Carpentier, I Horvath, J Olah, A Duchesnay, F Orosz, ...
Biochimica et Biophysica Acta (BBA)-General Subjects 1770 (6), 919-926, 2007
632007
Cross-talk between amyloidogenic proteins in type-2 diabetes and Parkinson’s disease
I Horvath, P Wittung-Stafshede
Proceedings of the National Academy of Sciences 113 (44), 12473-12477, 2016
372016
Interaction of TPPP/p25 protein with glyceraldehyde‐3‐phosphate dehydrogenase and their co‐localization in Lewy bodies
J Oláh, N Tőkési, O Vincze, I Horváth, A Lehotzky, A Erdei, E Szájli, ...
FEBS letters 580 (25), 5807-5814, 2006
352006
Pro-inflammatory S100A9 protein as a robust biomarker differentiating early stages of cognitive impairment in Alzheimer’s disease
I Horvath, X Jia, P Johansson, C Wang, R Moskalenko, A Steinau, ...
ACS chemical neuroscience 7 (1), 34-39, 2016
342016
The Structure of the Complex of Calmodulin with KAR-2 A NOVEL MODE OF BINDING EXPLAINS THE UNIQUE PHARMACOLOGY OF THE DRUG
I Horváth, V Harmat, A Perczel, V Pálfi, L Nyitray, A Nagy, E Hlavanda, ...
Journal of Biological Chemistry 280 (9), 8266-8274, 2005
272005
Phosphoenolpyruvate-dependent tubulin-pyruvate kinase interaction at different organizational levels
J Kovács, P Löw, A Pácz, I Horváth, J Oláh, J Ovádi
Journal of Biological Chemistry 278 (9), 7126-7130, 2003
232003
Modulation of α-synuclein fibrillization by ring-fused 2-pyridones: templation and inhibition involve oligomers with different structure
I Horvath, M Sellstedt, C Weise, LM Nordvall, G Krishna Prasad, ...
Archives of Biochemistry and Biophysics, 2013
222013
Direct correlation between ligand-induced α-synuclein oligomers and amyloid-like fibril growth
MN Pedersen, V Foderŕ, I Horvath, A Van Maarschalkerweerd, KN Toft, ...
Scientific reports 5, 10422, 2015
212015
Immunochemical detection of α-synuclein autoantibodies in Parkinson’s disease: correlation between plasma and cerebrospinal fluid levels
I Horvath, IA Iashchishyn, L Forsgren, LA Morozova-Roche
ACS chemical neuroscience 8 (6), 1170-1176, 2017
182017
Unraveling amyloid formation paths of Parkinson's disease protein α-synuclein triggered by anionic vesicles
J Kiskis, I Horvath, P Wittung-Stafshede, S Rocha
Quarterly reviews of biophysics 50, 2017
142017
New anti-mitotic drugs with distinct anti-calmodulin activity
F Orosz, I Horváth, J Ovádi
Mini reviews in medicinal chemistry 6 (10), 1145-1157, 2006
132006
Extracellular vesicles from human pancreatic islets suppress human islet amyloid polypeptide amyloid formation
D Ribeiro, I Horvath, N Heath, R Hicks, A Forslöw, P Wittung-Stafshede
Proceedings of the National Academy of Sciences 114 (42), 11127-11132, 2017
102017
Co-aggregation of pro-inflammatory S100A9 with α-synuclein in Parkinson’s disease: ex vivo and in vitro studies
I Horvath, IA Iashchishyn, RA Moskalenko, C Wang, SKTS Wärmländer, ...
Journal of neuroinflammation 15 (1), 172, 2018
92018
S100A9-driven amyloid-neuroinflammatory cascade in traumatic brain injury as a precursor state for Alzheimer’s disease
C Wang, IA Iashchishyn, J Pansieri, S Nyström, O Klementieva, J Kara, ...
Scientific reports 8 (1), 1-16, 2018
62018
Tyrosine hydroxylase binding to phospholipid membranes prompts its amyloid aggregation and compromises bilayer integrity
A Baumann, A Jorge-Finnigan, K Jung-Kc, A Sauter, I Horvath, ...
Scientific reports 6, 39488, 2016
52016
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Articles 1–20