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Leslie Goo
Leslie Goo
Verifierad e-postadress på fredhutch.org
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HIV-1 neutralizing antibodies induced by native-like envelope trimers
RW Sanders, MJ van Gils, R Derking, D Sok, TJ Ketas, JA Burger, ...
Science 349 (6244), aac4223, 2015
5372015
Broadly neutralizing activity of Zika virus-immune sera identifies a single viral serotype
KA Dowd, CR DeMaso, RS Pelc, SD Speer, ARY Smith, L Goo, DJ Platt, ...
Cell reports 16 (6), 1485-1491, 2016
2302016
Early development of broadly neutralizing antibodies in HIV-1–infected infants
L Goo, V Chohan, R Nduati, J Overbaugh
Nature medicine 20 (6), 655-658, 2014
1922014
Virus-inclusive single-cell RNA sequencing reveals the molecular signature of progression to severe dengue
F Zanini, ML Robinson, D Croote, MK Sahoo, AM Sanz, E Ortiz-Lasso, ...
Proceedings of the National Academy of Sciences 115 (52), E12363-E12369, 2018
1392018
Deconstructing the antiviral neutralizing-antibody response: implications for vaccine development and immunity
LA VanBlargan, L Goo, TC Pierson
Microbiology and Molecular Biology Reviews 80 (4), 989-1010, 2016
1282016
A single mutation in the envelope protein modulates flavivirus antigenicity, stability, and pathogenesis
L Goo, LA VanBlargan, KA Dowd, MS Diamond, TC Pierson
PLoS pathogens 13 (2), e1006178, 2017
782017
A virus-like particle vaccine elicits broad neutralizing antibody responses in humans to all chikungunya virus genotypes
L Goo, KA Dowd, TY Lin, JR Mascola, BS Graham, JE Ledgerwood, ...
The Journal of infectious diseases 214 (10), 1487-1491, 2016
612016
The Zika virus envelope protein glycan loop regulates virion antigenicity
L Goo, CR DeMaso, RS Pelc, JE Ledgerwood, BS Graham, RJ Kuhn, ...
Virology 515, 191-202, 2018
532018
Mutations in HIV-1 envelope that enhance entry with the macaque CD4 receptor alter antibody recognition by disrupting quaternary interactions within the trimer
DF Boyd, D Peterson, BS Haggarty, APO Jordan, MJ Hogan, L Goo, ...
Journal of virology 89 (2), 894-907, 2015
522015
Zika virus is not uniquely stable at physiological temperatures compared to other flaviviruses
L Goo, KA Dowd, ARY Smith, RS Pelc, CR DeMaso, TC Pierson
MBio 7 (5), 10.1128/mbio. 01396-16, 2016
492016
Broadly neutralizing human antibodies against dengue virus identified by single B cell transcriptomics
ND Durham, A Agrawal, E Waltari, D Croote, F Zanini, M Fouch, ...
Elife 8, e52384, 2019
472019
Neutralizing antibody escape during HIV-1 mother-to-child transmission involves conformational masking of distal epitopes in envelope
L Goo, C Milligan, CA Simonich, R Nduati, J Overbaugh
Journal of virology 86 (18), 9566-9582, 2012
402012
A combination of broadly neutralizing HIV-1 monoclonal antibodies targeting distinct epitopes effectively neutralizes variants found in early infection
L Goo, Z Jalalian-Lechak, BA Richardson, J Overbaugh
Journal of virology 86 (19), 10857-10861, 2012
392012
A protective human monoclonal antibody targeting the West Nile virus E protein preferentially recognizes mature virions
L Goo, K Debbink, N Kose, G Sapparapu, MP Doyle, AW Wessel, ...
Nature microbiology 4 (1), 71-77, 2019
222019
HIV-1 maternal and infant variants show similar sensitivity to broadly neutralizing antibodies, but sensitivity varies by subtype
J Mabuka, L Goo, MM Omenda, R Nduati, J Overbaugh
Aids 27 (10), 1535-1544, 2013
222013
Broadly neutralizing activity of Zika virus-immune sera identifies a single viral serotype. Cell Rep 16: 1485–1491
KA Dowd, CR DeMaso, RS Pelc, SD Speer, ARY Smith, L Goo, DJ Platt, ...
152016
Dengue virus serotype 1 conformational dynamics confers virus strain-dependent patterns of neutralization by polyclonal sera
LA VanBlargan, PS Milutinovic, L Goo, CR DeMaso, AP Durbin, ...
Journal of virology 95 (23), 10.1128/jvi. 00956-21, 2021
82021
Effects of identity minimization on Moloney murine leukemia virus template recognition and frequent tertiary template-directed insertions during nonhomologous recombination
NK Duggal, L Goo, SR King, A Telesnitsky
Journal of virology 81 (22), 12156-12168, 2007
62007
Single B cell transcriptomics identifies multiple isotypes of broadly neutralizing antibodies against flaviviruses
J Lubow, LM Levoir, DK Ralph, L Belmont, M Contreras, ...
PLoS Pathogens 19 (10), e1011722, 2023
52023
A (class-) switch in the antibody response may distinguish primary from secondary dengue virus infection
L Levoir, L Goo
EBioMedicine 56, 2020
22020
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Artiklar 1–20