Dendritic cell-based immunotherapy: a basic review and recent advances J Constantino, C Gomes, A Falcão, BM Neves, MT Cruz Immunologic research 65, 798-810, 2017 | 210 | 2017 |
Antitumor dendritic cell–based vaccines: lessons from 20 years of clinical trials and future perspectives J Constantino, C Gomes, A Falcão, MT Cruz, BM Neves Translational Research 168, 74-95, 2016 | 157 | 2016 |
Molecular imaging with SPECT as a tool for drug development CM Gomes, AJ Abrunhosa, P Ramos, EKJ Pauwels Advanced drug delivery reviews 63 (7), 547-554, 2011 | 129 | 2011 |
Therapeutic implications of an enriched cancer stem-like cell population in a human osteosarcoma cell line SR Martins-Neves, ÁO Lopes, A Do Carmo, AA Paiva, PC Simões, ... BMC cancer 12, 1-16, 2012 | 120 | 2012 |
Chemotherapy induces stemness in osteosarcoma cells through activation of Wnt/β-catenin signaling SR Martins-Neves, DI Paiva-Oliveira, PM Wijers-Koster, AJ Abrunhosa, ... Cancer letters 370 (2), 286-295, 2016 | 118 | 2016 |
The kinetics of small extracellular vesicle delivery impacts skin tissue regeneration H Henriques-Antunes, RMS Cardoso, A Zonari, J Correia, EC Leal, ... ACS nano 13 (8), 8694-8707, 2019 | 110 | 2019 |
Multidrug resistance in cancer: its mechanism and its modulation. EK Pauwels, P Erba, G Mariani, CM Gomes Drug news & perspectives 20 (6), 371-377, 2007 | 103 | 2007 |
Intravenous administration of brain-targeted stable nucleic acid lipid particles alleviates Machado-Joseph disease neurological phenotype M Conceição, L Mendonça, C Nóbrega, C Gomes, P Costa, H Hirai, ... Biomaterials 82, 124-137, 2016 | 100 | 2016 |
Osteosarcoma Stem Cells Have Active Wnt/β‐catenin and Overexpress SOX2 and KLF4 SR Martins‐Neves, WE Corver, DI Paiva‐Oliveira, BEWM Van den Akker, ... Journal of cellular physiology 231 (4), 876-886, 2016 | 91 | 2016 |
Dendritic cell vaccines for cancer immunotherapy: the role of human conventional type 1 dendritic cells J Calmeiro, MA Carrascal, AR Tavares, DA Ferreira, C Gomes, A Falcão, ... Pharmaceutics 12 (2), 158, 2020 | 90 | 2020 |
IWR-1, a tankyrase inhibitor, attenuates Wnt/β-catenin signaling in cancer stem-like cells and inhibits in vivo the growth of a subcutaneous human osteosarcoma xenograft SR Martins-Neves, DI Paiva-Oliveira, C Fontes-Ribeiro, JVMG Bovee, ... Cancer Letters 414, 1-15, 2018 | 83 | 2018 |
Presence of Cx43 in extracellular vesicles reduces the cardiotoxicity of the anti-tumour therapeutic approach with doxorubicin T Martins-Marques, MJ Pinho, M Zuzarte, C Oliveira, P Pereira, ... Journal of extracellular vesicles 5 (1), 32538, 2016 | 83 | 2016 |
Multidrug resistance mediated by ABC transporters in osteosarcoma cell lines: mRNA analysis and functional radiotracer studies CMF Gomes, H van Paassen, S Romeo, MM Welling, RIJ Feitsma, ... Nuclear medicine and biology 33 (7), 831-840, 2006 | 63 | 2006 |
Therapy-induced enrichment of cancer stem-like cells in solid human tumors: Where do we stand? SR Martins-Neves, AM Cleton-Jansen, CMF Gomes Pharmacological research 137, 193-204, 2018 | 60 | 2018 |
Phthalocyanine labels for near-infrared fluorescence imaging of solid tumors ACS Lobo, AD Silva, VA Tome, SMA Pinto, EFF Silva, MJF Calvete, ... Journal of medicinal chemistry 59 (10), 4688-4696, 2016 | 58 | 2016 |
Natural killer cell-based adoptive immunotherapy eradicates and drives differentiation of chemoresistant bladder cancer stem-like cells M Ferreira-Teixeira, D Paiva-Oliveira, B Parada, V Alves, V Sousa, ... BMC medicine 14, 1-13, 2016 | 53 | 2016 |
DIMP 53‐1: a novel small‐molecule dual inhibitor of p53–MDM 2/X interactions with multifunctional p53‐dependent anticancer properties J Soares, M Espadinha, L Raimundo, H Ramos, AS Gomes, S Gomes, ... Molecular Oncology 11 (6), 612-627, 2017 | 47 | 2017 |
Mitochondria-targeted photodynamic therapy with a galactodendritic chlorin to enhance cell death in resistant bladder cancer cells PMR Pereira, S Silva, M Bispo, M Zuzarte, C Gomes, H Girão, ... Bioconjugate Chemistry 27 (11), 2762-2769, 2016 | 44 | 2016 |
Reactivation of wild-type and mutant p53 by tryptophanolderived oxazoloisoindolinone SLMP53-1, a novel anticancer small-molecule J Soares, L Raimundo, NAL Pereira, Â Monteiro, S Gomes, C Bessa, ... Oncotarget 7 (4), 4326, 2016 | 44 | 2016 |
The interplay between glioblastoma and microglia cells leads to endothelial cell monolayer dysfunction via the interleukin‐6‐induced JAK2/STAT3 pathway M Couto, V Coelho‐Santos, L Santos, C Fontes‐Ribeiro, AP Silva, ... Journal of cellular physiology 234 (11), 19750-19760, 2019 | 43 | 2019 |