Följ
Faten A. Sayed
Faten A. Sayed
Verifierad e-postadress på alumni.ucsf.edu
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SIRT1 deficiency in microglia contributes to cognitive decline in aging and neurodegeneration via epigenetic regulation of IL-1β
SH Cho, JA Chen, F Sayed, ME Ward, F Gao, TA Nguyen, G Krabbe, ...
Journal of Neuroscience 35 (2), 807-818, 2015
2622015
Targeting microglia for the treatment of Alzheimer's Disease
PD Wes, FA Sayed, F Bard, L Gan
Glia 64 (10), 1710-1732, 2016
1882016
Critical data‐based re‐evaluation of minocycline as a putative specific microglia inhibitor
T Möller, F Bard, A Bhattacharya, K Biber, B Campbell, E Dale, C Eder, ...
Glia 64 (10), 1788-1794, 2016
1642016
Proximal recolonization by self-renewing microglia re-establishes microglial homeostasis in the adult mouse brain
L Zhan, G Krabbe, F Du, I Jones, MC Reichert, M Telpoukhovskaia, ...
PLoS biology 17 (2), e3000134, 2019
1372019
Differential effects of partial and complete loss of TREM2 on microglial injury response and tauopathy
FA Sayed, M Telpoukhovskaia, L Kodama, Y Li, Y Zhou, D Le, A Hauduc, ...
Proceedings of the National Academy of Sciences 115 (40), 10172-10177, 2018
1232018
Microglial NFκB-TNFα hyperactivation induces obsessive–compulsive behavior in mouse models of progranulin-deficient frontotemporal dementia
G Krabbe, SS Minami, JI Etchegaray, P Taneja, B Djukic, D Davalos, D Le, ...
Proceedings of the National Academy of Sciences 114 (19), 5029-5034, 2017
1152017
Microglial microRNAs mediate sex-specific responses to tau pathology
L Kodama, E Guzman, JI Etchegaray, Y Li, FA Sayed, L Zhou, Y Zhou, ...
Nature neuroscience 23 (2), 167-171, 2020
842020
AD-linked R47H-TREM2 mutation induces disease-enhancing microglial states via AKT hyperactivation
FA Sayed, L Kodama, L Fan, GK Carling, JC Udeochu, D Le, Q Li, L Zhou, ...
Science Translational Medicine 13 (622), eabe3947, 2021
572021
TREM2 and amyloid beta: a love-hate relationship
J Udeochu, FA Sayed, L Gan
Neuron 97 (5), 991-993, 2018
192018
Discovery of small molecules that normalize the transcriptome and enhance cysteine cathepsin activity in progranulin-deficient microglia
MA Telpoukhovskaia, K Liu, FA Sayed, JI Etchegaray, M Xie, L Zhan, Y Li, ...
Scientific reports 10 (1), 13688, 2020
172020
Alzheimer risk-increasing TREM2 variant causes aberrant cortical synapse density and promotes network hyperexcitability in mouse models
M Das, W Mao, Y Voskobiynyk, D Necula, I Lew, C Petersen, A Zahn, ...
Neurobiology of disease 186, 106263, 2023
52023
AD-linked R47H-TREM2 mutation induces disease-enhancing proinflammatory microglial states in mice and humans
FA Sayed, L Kodama, JC Udeochu, L Fan, GK Carling, D Le, Q Li, L Zhou, ...
bioRxiv, 2020.07. 24.218719, 2020
52020
F1‐07‐01: ASTROGLIAL AND MICROGLIAL MODULATION OF NEURAL FUNCTIONS IN MODELS OF ALZHEIMER'S DISEASE
L Mucke, K Akassoglou, M Das, L Gan, K Ho, M Merlini, A Orr, VA Rafalski, ...
Alzheimer's & Dementia 15, P188-P188, 2019
2019
P4‐511: A NOVEL ROLE FOR THE FTD‐CAUSING PROTEIN PROGRANULIN IN APOPTOSIS SIGNALING
C Clelland, JI Etchegaray, L Kodama, F Sayed, A Sachdev, Y Li, D Le, ...
Alzheimer's & Dementia 15, P1509-P1509, 2019
2019
Identifying compounds that restore normal cellular function in Frontotemporal dementia caused by progranulin haploinsufficiency
M Telpoukhovskaia, K Liu, F Sayed, JI Etchegaray, Y Zhou, D Le, M Xie, ...
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 256, 2018
2018
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Artiklar 1–15