Mammalian mitochondrial complex I: biogenesis, regulation, and reactive oxygen species generation WJH Koopman, LGJ Nijtmans, CEJ Dieteren, P Roestenberg, F Valsecchi, ... Antioxidants & redox signaling 12 (12), 1431-1470, 2010 | 474 | 2010 |
Insulin-like growth factor-1 sustains stem cell–mediated renal repair B Imberti, M Morigi, S Tomasoni, C Rota, D Corna, L Longaretti, D Rottoli, ... Journal of the American Society of Nephrology 18 (11), 2921-2928, 2007 | 383 | 2007 |
Depletion of PINK1 affects mitochondrial metabolism, calcium homeostasis and energy maintenance B Heeman, C Van den Haute, SA Aelvoet, F Valsecchi, RJ Rodenburg, ... Journal of cell science 124 (7), 1115-1125, 2011 | 220 | 2011 |
cAMP and mitochondria F Valsecchi, LS Ramos-Espiritu, J Buck, LR Levin, G Manfredi Physiology 28 (3), 199-209, 2013 | 182 | 2013 |
Rewiring of glutamine metabolism is a bioenergetic adaptation of human cells with mitochondrial DNA mutations Q Chen, K Kirk, YI Shurubor, D Zhao, AJ Arreguin, I Shahi, F Valsecchi, ... Cell metabolism 27 (5), 1007-1025. e5, 2018 | 167 | 2018 |
Mitochondrial complex III stabilizes complex I in the absence of NDUFS4 to provide partial activity MA Calvaruso, P Willems, M van den Brand, F Valsecchi, S Kruse, ... Human molecular genetics 21 (1), 115-120, 2012 | 134 | 2012 |
Discovery of LRE1 as a specific and allosteric inhibitor of soluble adenylyl cyclase L Ramos-Espiritu, S Kleinboelting, FA Navarrete, A Alvau, PE Visconti, ... Nature chemical biology 12 (10), 838-844, 2016 | 86 | 2016 |
Trolox-sensitive reactive oxygen species regulate mitochondrial morphology, oxidative phosphorylation and cytosolic calcium handling in healthy cells F Distelmaier, F Valsecchi, M Forkink, S Van Emst-De Vries, HG Swarts, ... Antioxidants & redox signaling 17 (12), 1657-1669, 2012 | 84 | 2012 |
In vitro and in vivo studies of the ALS-FTLD protein CHCHD10 reveal novel mitochondrial topology and protein interactions SR Burstein, F Valsecchi, H Kawamata, M Bourens, R Zeng, A Zuberi, ... Human molecular genetics 27 (1), 160-177, 2018 | 81 | 2018 |
Metabolic consequences of NDUFS4 gene deletion in immortalized mouse embryonic fibroblasts F Valsecchi, C Monge, M Forkink, AJC De Groof, G Benard, R Rossignol, ... Biochimica et Biophysica Acta (BBA)-Bioenergetics 1817 (10), 1925-1936, 2012 | 72 | 2012 |
Mitochondrial Ca2+ homeostasis in human NADH: ubiquinone oxidoreductase deficiency PHGM Willems, F Valsecchi, F Distelmaier, S Verkaart, HJ Visch, ... Cell calcium 44 (1), 123-133, 2008 | 71 | 2008 |
Complex I disorders: causes, mechanisms, and development of treatment strategies at the cellular level F Valsecchi, WJH Koopman, GR Manjeri, RJ Rodenburg, JAM Smeitink, ... Developmental disabilities research reviews 16 (2), 175-182, 2010 | 65 | 2010 |
Role of soluble adenylyl cyclase in mitochondria F Valsecchi, C Konrad, G Manfredi Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease 1842 (12 …, 2014 | 63 | 2014 |
Fractalkine and CX3CR1 mediate leukocyte capture by endothelium in response to Shiga toxin C Zanchi, C Zoja, M Morigi, F Valsecchi, XY Liu, D Rottoli, M Locatelli, ... The Journal of Immunology 181 (2), 1460-1469, 2008 | 62 | 2008 |
Differential susceptibility of mitochondrial complex II to inhibition by oxaloacetate in brain and heart A Stepanova, Y Shurubor, F Valsecchi, G Manfredi, A Galkin Biochimica et Biophysica Acta (BBA)-Bioenergetics 1857 (9), 1561-1568, 2016 | 60 | 2016 |
Primary fibroblasts of NDUFS4−/− mice display increased ROS levels and aberrant mitochondrial morphology F Valsecchi, S Grefte, P Roestenberg, J Joosten-Wagenaars, ... Mitochondrion 13 (5), 436-443, 2013 | 55 | 2013 |
Mitochondrial dysfunction in primary human fibroblasts triggers an adaptive cell survival program that requires AMPK-α F Distelmaier, F Valsecchi, DC Liemburg-Apers, M Lebiedzinska, ... Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease 1852 (3), 529-540, 2015 | 52 | 2015 |
Pharmacological targeting of mitochondrial complex I deficiency: the cellular level and beyond P Roestenberg, GR Manjeri, F Valsecchi, JAM Smeitink, PHGM Willems, ... Mitochondrion 12 (1), 57-65, 2012 | 49 | 2012 |
Bioenergetic markers in skin fibroblasts of sporadic amyotrophic lateral sclerosis and progressive lateral sclerosis patients K Kirk, C Gennings, JC Hupf, S Tadesse, M D'Aurelio, H Kawamata, ... Annals of neurology 76 (4), 620-624, 2014 | 48 | 2014 |
Mutant TDP-43 does not impair mitochondrial bioenergetics in vitro and in vivo. MG Kawamata H, Peixoto P, Konrad C, Palomo G, Bredvik K, Gerges M, Valsecchi ... Mol Neurodegener, 2017 | 41 | 2017 |