| Discovery and development of the G-rich oligonucleotide AS1411 as a novel treatment for cancer PJ Bates, DA Laber, DM Miller, SD Thomas, JO Trent Experimental and molecular pathology 86 (3), 151-164, 2009 | 922 | 2009 |
| Antiproliferative activity of G-rich oligonucleotides correlates with protein binding PJ Bates, JB Kahlon, SD Thomas, JO Trent, DM Miller Journal of Biological Chemistry 274 (37), 26369-26377, 1999 | 501 | 1999 |
| Biophysical and biological properties of quadruplex oligodeoxyribonucleotides V Đapić, V Abdomerović, R Marrington, J Peberdy, A Rodger, JO Trent, ... Nucleic acids research 31 (8), 2097-2107, 2003 | 467 | 2003 |
| A new paradigm for aptamer therapeutic AS1411 action: uptake by macropinocytosis and its stimulation by a nucleolin-dependent mechanism EM Reyes-Reyes, Y Teng, PJ Bates Cancer research 70 (21), 8617-8629, 2010 | 388 | 2010 |
| AGRO100 inhibits activation of nuclear factor-κB (NF-κB) by forming a complex with NF-κB essential modulator (NEMO) and nucleolin AC Girvan, Y Teng, LK Casson, SD Thomas, S Juliger, MW Ball, JB Klein, ... Molecular cancer therapeutics 5 (7), 1790-1799, 2006 | 292 | 2006 |
| G-quadruplex oligonucleotide AS1411 as a cancer-targeting agent: Uses and mechanisms PJ Bates, EM Reyes-Reyes, MT Malik, EM Murphy, MG O'toole, JO Trent Biochimica et Biophysica Acta (BBA)-General Subjects 1861 (5), 1414-1428, 2017 | 271 | 2017 |
| Inhibition of DNA replication and induction of S phase cell cycle arrest by G-rich oligonucleotides X Xu, F Hamhouyia, SD Thomas, TJ Burke, AC Girvan, WG McGregor, ... Journal of Biological Chemistry 276 (46), 43221-43230, 2001 | 237 | 2001 |
| Antiproliferative activity of G-quartet-forming oligonucleotides with backbone and sugar modifications V Đapić, PJ Bates, JO Trent, A Rodger, SD Thomas, DM Miller Biochemistry 41 (11), 3676-3685, 2002 | 197 | 2002 |
| AS1411 alters the localization of a complex containing protein arginine methyltransferase 5 and nucleolin Y Teng, AC Girvan, LK Casson, WM Pierce Jr, M Qian, SD Thomas, ... Cancer research 67 (21), 10491-10500, 2007 | 179 | 2007 |
| Mechanistic studies of anticancer aptamer AS1411 reveal a novel role for nucleolin in regulating Rac1 activation EM Reyes-Reyes, FR Šalipur, M Shams, MK Forsthoefel, PJ Bates Molecular oncology 9 (7), 1392-1405, 2015 | 174 | 2015 |
| Apoptosis in leukemia cells is accompanied by alterations in the levels and localization of nucleolin Y Mi, SD Thomas, X Xu, LK Casson, DM Miller, PJ Bates Journal of Biological Chemistry 278 (10), 8572-8579, 2003 | 173 | 2003 |
| Resolution and characterization of the structural polymorphism of a single quadruplex-forming sequence MM Dailey, MC Miller, PJ Bates, AN Lane, JO Trent Nucleic acids research 38 (14), 4877-4888, 2010 | 169 | 2010 |
| DNA binding of ruthenium tris (1, 10-phenanthroline): evidence for the dependence of binding mode on metal complex concentration DZM Coggan, IS Haworth, PJ Bates, A Robinson, A Rodger Inorganic chemistry 38 (20), 4486-4497, 1999 | 143 | 1999 |
| AS1411-conjugated gold nanospheres and their potential for breast cancer therapy MT Malik, MG O'Toole, LK Casson, SD Thomas, GT Bardi, ... Oncotarget 6 (26), 22270, 2015 | 111 | 2015 |
| Cancer-selective antiproliferative activity is a general property of some G-rich oligodeoxynucleotides EW Choi, LV Nayak, PJ Bates Nucleic acids research 38 (5), 1623-1635, 2010 | 106 | 2010 |
| Quartets in G‐major: The first international meeting on quadruplex DNA P Bates, JL Mergny, D Yang EMBO reports 8 (11), 1003-1010, 2007 | 99 | 2007 |
| Detection and kinetic studies of triplex formation by oligodeoxynucleotides using real-time biomolecular interaction analysis (BIA) PJ Bates, HS Dosanjh, S Kumar, TC Jenkins, CA Laughton, S Neidle Nucleic acids research 23 (18), 3627-3632, 1995 | 90 | 1995 |
| Oncogenic synergism between ErbB1, nucleolin, and mutant Ras K Farin, S Schokoroy, R Haklai, I Cohen-Or, G Elad-Sfadia, ... Cancer research 71 (6), 2140-2151, 2011 | 86 | 2011 |
| Aptamer imaging with Cu-64 labeled AS1411: preliminary assessment in lung cancer J Li, H Zheng, PJ Bates, T Malik, XF Li, JO Trent, CK Ng Nuclear medicine and biology 41 (2), 179-185, 2014 | 76 | 2014 |
| Efficient triple helix formation by oligodeoxyribonucleotides containing α-or β-2-amino-5-(2-deoxy-D-ribofuranosyl) pyridine residues PJ Bates, CA Laughton, TC Jenkins, DC Capaldi, PD Roselt, CB Reese, ... Nucleic acids research 24 (21), 4176-4184, 1996 | 70 | 1996 |
Martin O'TooleUniversity of LouisvilleVerified email at louisville.edu
