PAX3–FOXO1 establishes myogenic super enhancers and confers BET bromodomain vulnerability BE Gryder, ME Yohe, HC Chou, X Zhang, J Marques, M Wachtel, ... Cancer Discovery 7 (8), 884-899, 2017 | 280 | 2017 |
Genomic classification and clinical outcome in rhabdomyosarcoma: a report from an international consortium JF Shern, J Selfe, E Izquierdo, R Patidar, HC Chou, YK Song, ME Yohe, ... Journal of Clinical Oncology 39 (26), 2859-2871, 2021 | 141 | 2021 |
MEK inhibition induces MYOG and remodels super-enhancers in RAS-driven rhabdomyosarcoma ME Yohe, BE Gryder, JF Shern, YK Song, HC Chou, S Sindiri, A Mendoza, ... Science translational medicine 10 (448), eaan4470, 2018 | 137 | 2018 |
Histone hyperacetylation disrupts core gene regulatory architecture in rhabdomyosarcoma BE Gryder, S Pomella, C Sayers, XS Wu, Y Song, AM Chiarella, S Bagchi, ... Nature genetics 51 (12), 1714-1722, 2019 | 136 | 2019 |
Comprehensive analysis of chromatin states in atypical teratoid/rhabdoid tumor identifies diverging roles for SWI/SNF and polycomb in gene regulation S Erkek, PD Johann, MA Finetti, Y Drosos, HC Chou, M Zapatka, D Sturm, ... Cancer cell 35 (1), 95-110. e8, 2019 | 80 | 2019 |
An optimized bicistronic chimeric antigen receptor against GPC2 or CD276 overcomes heterogeneous expression in neuroblastoma M Tian, AT Cheuk, JS Wei, A Abdelmaksoud, HC Chou, D Milewski, ... The Journal of Clinical Investigation 132 (16), 2022 | 44 | 2022 |
Immuno-transcriptomic profiling of extracranial pediatric solid malignancies AS Brohl, S Sindiri, JS Wei, D Milewski, HC Chou, YK Song, X Wen, ... Cell reports 37 (8), 2021 | 43 | 2021 |
Interaction between SNAI2 and MYOD enhances oncogenesis and suppresses differentiation in Fusion Negative Rhabdomyosarcoma S Pomella, P Sreenivas, BE Gryder, L Wang, D Milewski, M Cassandri, ... Nature communications 12 (1), 192, 2021 | 38 | 2021 |
BAF complexes drive proliferation and block myogenic differentiation in fusion-positive rhabdomyosarcoma D Laubscher, BE Gryder, BD Sunkel, T Andresson, M Wachtel, S Das, ... Nature Communications 12 (1), 6924, 2021 | 37 | 2021 |
Defining the transcriptomic landscape of the developing enteric nervous system and its cellular environment S Roy-Carson, K Natukunda, H Chou, N Pal, C Farris, SQ Schneider, ... BMC genomics 18, 1-24, 2017 | 36 | 2017 |
Expression of the wnt gene complement in a spiral-cleaving embryo and trochophore larva MM Pruitt, EJ Letcher, HC Chou, BR Bastin, SQ Schneider Int J Dev Biol 58 (6-8), 563-73, 2014 | 29 | 2014 |
A transcriptional blueprint for a spiral-cleaving embryo HC Chou, MM Pruitt, BR Bastin, SQ Schneider BMC genomics 17, 1-25, 2016 | 23 | 2016 |
PdumBase: a transcriptome database and research tool for Platynereis dumerilii and early development of other metazoans HC Chou, N Acevedo-Luna, JA Kuhlman, SQ Schneider BMC genomics 19, 1-11, 2018 | 22 | 2018 |
Structure, phylogeny, and expression of the frizzled-related gene family in the lophotrochozoan annelid Platynereis dumerilii BR Bastin, HC Chou, MM Pruitt, SQ Schneider EvoDevo 6, 1-24, 2015 | 21 | 2015 |
Tumor mutation burden, expressed neoantigens and the immune microenvironment in diffuse gliomas G Yu, Y Pang, M Merchant, C Kesserwan, V Gangalapudi, ... Cancers 13 (23), 6092, 2021 | 20 | 2021 |
Rhabdoid tumors are sensitive to the protein-translation inhibitor homoharringtonine TP Howard, EM Oberlick, MG Rees, TE Arnoff, MT Pham, L Brenan, ... Clinical Cancer Research 26 (18), 4995-5006, 2020 | 17 | 2020 |
SRAssembler: Selective Recursive local Assembly of homologous genomic regions TW McCarthy, H Chou, VP Brendel BMC bioinformatics 20, 1-13, 2019 | 13 | 2019 |
Genomic and transcriptomic analysis of relapsed and refractory childhood solid tumors reveals a diverse molecular landscape and mechanisms of immune evasion SA Byron, WPD Hendricks, AB Nagulapally, JM Kraveka, WS Ferguson, ... Cancer research 81 (23), 5818-5832, 2021 | 11 | 2021 |
A stem cell epigenome is associated with primary nonresponse to CD19 CAR T cells in pediatric acute lymphoblastic leukemia KE Masih, RA Gardner, HC Chou, A Abdelmaksoud, YK Song, L Mariani, ... Blood Advances 7 (15), 4218-4232, 2023 | 10 | 2023 |
The asymmetric cell division machinery in the spiral-cleaving egg and embryo of the marine annelid Platynereis dumerilii AB Nakama, HC Chou, SQ Schneider BMC Developmental Biology 17, 1-22, 2017 | 9 | 2017 |