Hsien-chao Chou
Hsien-chao Chou
National Cancer Institute
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PAX3–FOXO1 establishes myogenic super enhancers and confers BET bromodomain vulnerability
BE Gryder, ME Yohe, HC Chou, X Zhang, J Marques, M Wachtel, ...
Cancer Discovery 7 (8), 884-899, 2017
MEK inhibition induces MYOG and remodels super-enhancers in RAS-driven rhabdomyosarcoma
ME Yohe, BE Gryder, JF Shern, YK Song, HC Chou, S Sindiri, A Mendoza, ...
Science translational medicine 10 (448), eaan4470, 2018
Histone hyperacetylation disrupts core gene regulatory architecture in rhabdomyosarcoma
BE Gryder, S Pomella, C Sayers, XS Wu, Y Song, AM Chiarella, S Bagchi, ...
Nature genetics 51 (12), 1714-1722, 2019
Genomic classification and clinical outcome in rhabdomyosarcoma: a report from an international consortium
JF Shern, J Selfe, E Izquierdo, R Patidar, HC Chou, YK Song, ME Yohe, ...
Journal of Clinical Oncology 39 (26), 2859, 2021
Comprehensive analysis of chromatin states in atypical teratoid/rhabdoid tumor identifies diverging roles for SWI/SNF and polycomb in gene regulation
S Erkek, PD Johann, MA Finetti, Y Drosos, HC Chou, M Zapatka, D Sturm, ...
Cancer cell 35 (1), 95-110. e8, 2019
An optimized bicistronic chimeric antigen receptor against GPC2 or CD276 overcomes heterogeneous expression in neuroblastoma
M Tian, AT Cheuk, JS Wei, A Abdelmaksoud, HC Chou, D Milewski, ...
The Journal of Clinical Investigation 132 (16), 2022
Interaction between SNAI2 and MYOD enhances oncogenesis and suppresses differentiation in Fusion Negative Rhabdomyosarcoma
S Pomella, P Sreenivas, BE Gryder, L Wang, D Milewski, M Cassandri, ...
Nature communications 12 (1), 192, 2021
Immuno-transcriptomic profiling of extracranial pediatric solid malignancies
AS Brohl, S Sindiri, JS Wei, D Milewski, HC Chou, YK Song, X Wen, ...
Cell reports 37 (8), 2021
Defining the transcriptomic landscape of the developing enteric nervous system and its cellular environment
S Roy-Carson, K Natukunda, H Chou, N Pal, C Farris, SQ Schneider, ...
BMC genomics 18, 1-24, 2017
BAF complexes drive proliferation and block myogenic differentiation in fusion-positive rhabdomyosarcoma
D Laubscher, BE Gryder, BD Sunkel, T Andresson, M Wachtel, S Das, ...
Nature Communications 12 (1), 6924, 2021
Expression of the wnt gene complement in a spiral-cleaving embryo and trochophore larva
MM Pruitt, EJ Letcher, HC Chou, BR Bastin, SQ Schneider
International Journal of Developmental Biology 58 (6-7-8), 563-573, 2014
A transcriptional blueprint for a spiral-cleaving embryo
HC Chou, MM Pruitt, BR Bastin, SQ Schneider
BMC genomics 17, 1-25, 2016
PdumBase: a transcriptome database and research tool for Platynereis dumerilii and early development of other metazoans
HC Chou, N Acevedo-Luna, JA Kuhlman, SQ Schneider
BMC genomics 19, 1-11, 2018
Structure, phylogeny, and expression of the frizzled-related gene family in the lophotrochozoan annelid Platynereis dumerilii
BR Bastin, HC Chou, MM Pruitt, SQ Schneider
EvoDevo 6, 1-24, 2015
Tumor mutation burden, expressed neoantigens and the immune microenvironment in diffuse gliomas
G Yu, Y Pang, M Merchant, C Kesserwan, V Gangalapudi, ...
Cancers 13 (23), 6092, 2021
Rhabdoid tumors are sensitive to the protein-translation inhibitor homoharringtonine
TP Howard, EM Oberlick, MG Rees, TE Arnoff, MT Pham, L Brenan, ...
Clinical Cancer Research 26 (18), 4995-5006, 2020
SRAssembler: Selective Recursive local Assembly of homologous genomic regions
TW McCarthy, H Chou, VP Brendel
BMC bioinformatics 20, 1-13, 2019
Genomic and transcriptomic analysis of relapsed and refractory childhood solid tumors reveals a diverse molecular landscape and mechanisms of immune evasion
SA Byron, WPD Hendricks, AB Nagulapally, JM Kraveka, WS Ferguson, ...
Cancer research 81 (23), 5818-5832, 2021
The asymmetric cell division machinery in the spiral-cleaving egg and embryo of the marine annelid Platynereis dumerilii
AB Nakama, HC Chou, SQ Schneider
BMC Developmental Biology 17, 1-22, 2017
A stem cell epigenome is associated with primary nonresponse to CD19 CAR T cells in pediatric acute lymphoblastic leukemia
KE Masih, RA Gardner, HC Chou, A Abdelmaksoud, YK Song, L Mariani, ...
Blood Advances 7 (15), 4218-4232, 2023
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