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M Omar-Hmeadi
M Omar-Hmeadi
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Functional, metabolic and transcriptional maturation of human pancreatic islets derived from stem cells
D Balboa, T Barsby, V Lithovius, J Saarimäki-Vire, M Omar-Hmeadi, ...
Nature biotechnology 40 (7), 1042-1055, 2022
1702022
Glucose-dependent granule docking limits insulin secretion and is decreased in human type 2 diabetes
NR Gandasi, P Yin, M Omar-Hmeadi, EO Laakso, P Vikman, S Barg
Cell metabolism 27 (2), 470-478. e4, 2018
932018
Paracrine control of α-cell glucagon exocytosis is compromised in human type-2 diabetes
M Omar-Hmeadi, PE Lund, NR Gandasi, A Tengholm, S Barg
Nature communications 11 (1), 1896, 2020
802020
Insulin granule biogenesis and exocytosis
M Omar-Hmeadi, O Idevall-Hagren
Cellular and Molecular Life Sciences 78, 1957-1970, 2021
702021
Endoplasmic reticulum chaperone glucose-regulated protein 94 is essential for proinsulin handling
SM Ghiasi, T Dahlby, C Hede Andersen, L Haataja, S Petersen, ...
Diabetes 68 (4), 747-760, 2019
702019
Fusion pore regulation by cAMP/Epac2 controls cargo release during insulin exocytosis
A Guček, NR Gandasi, M Omar-Hmeadi, M Bakke, SO Døskeland, ...
Elife 8, e41711, 2019
462019
Alternative splicing encodes functional intracellular CD59 isoforms that mediate insulin secretion and are down-regulated in diabetic islets
E Golec, A Ekström, M Noga, M Omar-Hmeadi, PE Lund, BO Villoutreix, ...
Proceedings of the National Academy of Sciences 119 (24), e2120083119, 2022
172022
Syntaxin clusters at secretory granules in a munc18-bound conformation
P Yin, NR Gandasi, S Arora, M Omar-Hmeadi, J Saras, S Barg
Molecular biology of the cell 29 (22), 2700-2708, 2018
142018
PtdIns(4,5)P2 is not required for secretory granule docking
M Omar‐Hmeadi, NR Gandasi, S Barg
Traffic 19 (6), 436-445, 2018
132018
Functional, metabolic and transcriptional maturation of stem cell derived beta cells
D Balboa, T Barsby, V Lithovius, J Saarimäki-Vire, M Omar-Hmeadi, ...
bioRxiv, 2021.03. 31.437748, 2021
82021
Fusion pore regulation by Epac2/cAMP controls cargo release during insulin exocytosis
A Gucek, NR Gandasi, M Omar-Hmeadi, M Bakke, S Doskeland, ...
Biophysical Journal 116 (3), 314a, 2019
32019
Local PI (4, 5) P2 signaling inhibits fusion pore expansion during exocytosis
M Omar-Hmeadi, A Guček, S Barg
Cell Reports 42 (2), 2023
22023
A spatiotemporal proteomic map of human adipogenesis
F Klingelhuber, S Frendo-Cumbo, M Omar-Hmeadi, L Massier, ...
Nature Metabolism, 1-19, 2024
12024
Transcriptional determinants of lipid mobilization in human adipocytes
AC Ludzki, M Hansen, D Zareifi, J Jalkanen, Z Huang, M Omar-Hmeadi, ...
Science Advances 10 (1), eadi2689, 2024
12024
Adipogenic characterization of immortalized CD55+ progenitor cells from human white adipose tissue
M Couchet, H Gao, F Klingelhuber, J Jalkanen, T De Castro Barbosa, ...
Adipocyte, 2283213, 2023
12023
A Spatiotemporal Proteomic Map of Human Adipogenesis
N Krahmer, F Klingelhuber, S Frendo-Cumbo, O Hmeadi, AJ Taylor, ...
2023
RFX6 haploinsufficiency predisposes to diabetes through impaired beta cell functionality
H Ibrahim, D Balboa, J Saarimäki-Vire, H Montaser, O Dyachok, PE Lund, ...
bioRxiv, 2023.11. 15.567202, 2023
2023
Quantification of Secretory Granule Exocytosis by TIRF Imaging and Capacitance Measurements
M Omar-Hmeadi, L Liu, S Echeverry, S Barg
Chromaffin Cells: Methods and Protocols, 179-186, 2022
2022
Local PI(4,5)P2 generation controls fusion pore expansion during exocytosis
M Omar-Hmeadi, A Guček, S Barg
bioRxiv, 2022.01. 26.477824, 2022
2022
Kantasoluista tuotettiin toimivia beetasoluja
D Balboa, T Barsby, V Lithovius, J Saarimäki-Vire, M Omar-Hmeadi, ...
Duodecim 138 (8), 727, 2022
2022
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Artiklar 1–20