| The 2019 mathematical oncology roadmap RC Rockne, A Hawkins-Daarud, KR Swanson, JP Sluka, JA Glazier, ... Physical biology 16 (4), 041005, 2019 | 169 | 2019 |
| Steering evolution with sequential therapy to prevent the emergence of bacterial antibiotic resistance D Nichol, P Jeavons, AG Fletcher, RA Bonomo, PK Maini, JL Paul, ... PLoS computational biology 11 (9), e1004493, 2015 | 165 | 2015 |
| Antibiotic collateral sensitivity is contingent on the repeatability of evolution D Nichol, J Rutter, C Bryant, AM Hujer, S Lek, MD Adams, P Jeavons, ... Nature communications 10 (1), 334, 2019 | 155 | 2019 |
| Subclonal reconstruction of tumors by using machine learning and population genetics G Caravagna, T Heide, MJ Williams, L Zapata, D Nichol, K Chkhaidze, ... Nature Genetics 52 (9), 898-907, 2020 | 93 | 2020 |
| Collateral sensitivity networks reveal evolutionary instability and novel treatment strategies in ALK mutated non-small cell lung cancer A Dhawan, D Nichol, F Kinose, ME Abazeed, A Marusyk, EB Haura, ... Scientific reports 7 (1), 1232, 2017 | 92 | 2017 |
| Exploiting evolutionary steering to induce collateral drug sensitivity in cancer A Acar, D Nichol, J Fernandez-Mateos, GD Cresswell, I Barozzi, SP Hong, ... Nature communications 11 (1), 1923, 2020 | 90 | 2020 |
| Phenotypic plasticity and genetic control in colorectal cancer evolution J Househam, T Heide, GD Cresswell, I Spiteri, C Kimberley, L Zapata, ... Nature 611 (7937), 744-753, 2022 | 75 | 2022 |
| Evolutionary dynamics of residual disease in human glioblastoma I Spiteri, G Caravagna, GD Cresswell, A Vatsiou, D Nichol, A Acar, ... Annals of Oncology 30 (3), 456-463, 2019 | 65 | 2019 |
| Measuring single cell divisions in human tissues from multi-region sequencing data B Werner, J Case, MJ Williams, K Chkhaidze, D Temko, ... Nature communications 11 (1), 1035, 2020 | 59 | 2020 |
| The co-evolution of the genome and epigenome in colorectal cancer T Heide, J Househam, GD Cresswell, I Spiteri, C Lynn, M Mossner, ... Nature 611 (7937), 733-743, 2022 | 53 | 2022 |
| Stochasticity in the Genotype-Phenotype Map: Implications for the Robustness and Persistence of Bet-Hedging D Nichol, M Robertson-Tessi, P Jeavons, ARA Anderson Genetics 204 (4), 1523-1539, 2016 | 44 | 2016 |
| Mapping the breast cancer metastatic cascade onto ctDNA using genetic and epigenetic clonal tracking GD Cresswell, D Nichol, I Spiteri, H Tari, L Zapata, T Heide, CC Maley, ... Nature communications 11 (1), 1446, 2020 | 43 | 2020 |
| Colorectal cancer residual disease at maximal response to EGFR blockade displays a druggable Paneth cell–like phenotype B Lupo, F Sassi, M Pinnelli, F Galimi, ER Zanella, V Vurchio, G Migliardi, ... Science translational medicine 12 (555), eaax8313, 2020 | 40 | 2020 |
| The spatiotemporal evolution of lymph node spread in early breast cancer P Barry, A Vatsiou, I Spiteri, D Nichol, GD Cresswell, A Acar, N Trahearn, ... Clinical Cancer Research 24 (19), 4763-4770, 2018 | 37 | 2018 |
| Model genotype–phenotype mappings and the algorithmic structure of evolution D Nichol, M Robertson-Tessi, ARA Anderson, P Jeavons Journal of the Royal Society Interface 16 (160), 20190332, 2019 | 27 | 2019 |
| The role of memory in non-genetic inheritance and its impact on cancer treatment resistance T Cassidy, D Nichol, M Robertson-Tessi, M Craig, ARA Anderson PLoS computational biology 17 (8), e1009348, 2021 | 13 | 2021 |
| Combining radiomics and mathematical modeling to elucidate mechanisms of resistance to immune checkpoint blockade in non-small cell lung cancer D Saeed-Vafa, R Bravo, JA Dean, A El-Kenawi, N Mon Père, M Strobl, ... BioRxiv, 190561, 2017 | 13 | 2017 |
| Exploiting evolutionary herding to control drug resistance in cancer A Acar, D Nichol, J Fernandez-Mateos, GD Cresswell, I Barozzi, SP Hong, ... BioRxiv, 566950, 2019 | 9 | 2019 |
| A low-cost, open source, self-contained bacterial EVolutionary biorEactor (EVE) V Gopalakrishnan, NP Krishnan, E McClure, J Pelesko, D Crozier, ... bioRxiv, 729434, 2019 | 7 | 2019 |
| Model-based tumor subclonal reconstruction G Caravagna, T Heide, M Williams, L Zapata, D Nichol, K Chkhaidze, ... bioRxiv, 586560, 2019 | 6 | 2019 |
