| Oral druggable space beyond the rule of 5: insights from drugs and clinical candidates BC Doak, B Over, F Giordanetto, J Kihlberg Chemistry & biology 21 (9), 1115-1142, 2014 | 758 | 2014 |
| Macrocyclic drugs and clinical candidates: what can medicinal chemists learn from their properties? F Giordanetto, J Kihlberg Journal of medicinal chemistry 57 (2), 278-295, 2014 | 604 | 2014 |
| 2-(Trimethylsilyl) ethyl glycosides. 3. Synthesis, anomeric deblocking, and transformation into 1, 2-trans 1-O-acyl sugars K Jansson, S Ahlfors, T Frejd, J Kihlberg, G Magnusson, J Dahmen, ... The Journal of Organic Chemistry 53 (24), 5629-5647, 1988 | 385 | 1988 |
| How beyond rule of 5 drugs and clinical candidates bind to their targets BC Doak, J Zheng, D Dobritzsch, J Kihlberg Journal of medicinal chemistry 59 (6), 2312-2327, 2016 | 335 | 2016 |
| Structural basis of pilus subunit recognition by the PapD chaperone MJ Kuehn, DJ Ogg, J Kihlberg, LN Slonim, K Flemmer, T Bergfors, ... Science 262 (5137), 1234-1241, 1993 | 290 | 1993 |
| Cell permeability beyond the rule of 5 P Matsson, BC Doak, B Over, J Kihlberg Advanced drug delivery reviews 101, 42-61, 2016 | 281 | 2016 |
| Role of the human ST6GalNAc-I and ST6GalNAc-II in the synthesis of the cancer-associated sialyl-Tn antigen NT Marcos, S Pinho, C Grandela, A Cruz, B Samyn-Petit, ... Cancer research 64 (19), 7050-7057, 2004 | 277 | 2004 |
| How big is too big for cell permeability? P Matsson, J Kihlberg Journal of medicinal chemistry 60 (5), 1662-1664, 2017 | 266 | 2017 |
| Predominant selection of T cells specific for the glycosylated collagen type II epitope (263–270) in humanized transgenic mice and in rheumatoid arthritis J Bäcklund, S Carlsen, T Höger, B Holm, L Fugger, J Kihlberg, ... Proceedings of the National Academy of Sciences 99 (15), 9960-9965, 2002 | 258 | 2002 |
| The PapG adhesin of uropathogenic Escherichia coli contains separate regions for receptor binding and for the incorporation into the pilus. SJ Hultgren, F Lindberg, G Magnusson, J Kihlberg, JM Tennent, ... Proceedings of the National Academy of Sciences 86 (12), 4357-4361, 1989 | 246 | 1989 |
| Epitope glycosylation plays a critical role for T cell recognition of type II collagen in collagen‐induced arthritis A Corthay, J Bäcklund, J Broddefalk, E Michaelsson, TJ Goldschmidt, ... European journal of immunology 28 (8), 2580-2590, 1998 | 215 | 1998 |
| Impact of dynamically exposed polarity on permeability and solubility of chameleonic drugs beyond the rule of 5 M Rossi Sebastiano, BC Doak, M Backlund, V Poongavanam, B Over, ... Journal of medicinal chemistry 61 (9), 4189-4202, 2018 | 201 | 2018 |
| Structural and conformational determinants of macrocycle cell permeability B Over, P Matsson, C Tyrchan, P Artursson, BC Doak, MA Foley, ... Nature Chemical Biology 12 (12), 1065-1074, 2016 | 191 | 2016 |
| The in situ activation of thioglycosides with bromine: an improved glycosylation method JO Kihlberg, DA Leigh, DR Bundle The Journal of Organic Chemistry 55 (9), 2860-2863, 1990 | 190 | 1990 |
| Ultralarge virtual screening identifies SARS-CoV-2 main protease inhibitors with broad-spectrum activity against coronaviruses A Luttens, H Gullberg, E Abdurakhmanov, DD Vo, D Akaberi, VO Talibov, ... Journal of the American Chemical Society 144 (7), 2905-2920, 2022 | 179 | 2022 |
| Design and evaluation of pilicides: potential novel antibacterial agents directed against uropathogenic Escherichia coli A Svensson, A Larsson, H Emtenäs, M Hedenström, T Fex, SJ Hultgren, ... ChemBioChem (Print) 2 (12), 915-918, 2001 | 175 | 2001 |
| The sesquiterpenes of Lactarius vellereus and their role in a proposed chemical defense system O Sterner, R Bergman, J Kihlberg, B Wickberg Journal of Natural Products 48 (2), 279-288, 1985 | 169 | 1985 |
| Periplasmic chaperone recognition motif of subunits mediates quaternary interactions in the pilus GE Soto, KW Dodson, D Ogg, C Liu, J Heuser, S Knight, J Kihlberg, ... The EMBO journal, 1998 | 144 | 1998 |
| T cells specific for post-translational modifications escape intrathymic tolerance induction B Raposo, P Merky, C Lundqvist, H Yamada, V Urbonaviciute, C Niaudet, ... Nature communications 9 (1), 353, 2018 | 135 | 2018 |
| Preparation of building blocks for glycopeptide synthesis by glycosylation of Fmoc amino acids having unprotected carboxyl groups LA Salvador, M Elofsson, J Kihlberg Tetrahedron 51 (19), 5643-5656, 1995 | 132 | 1995 |
