Jason Mears
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Dnm1 forms spirals that are structurally tailored to fit mitochondria
E Ingerman, EM Perkins, M Marino, JA Mears, JM McCaffery, JE Hinshaw, ...
The Journal of cell biology 170 (7), 1021-1027, 2005
Conformational changes in Dnm1 support a contractile mechanism for mitochondrial fission
JA Mears, LL Lackner, S Fang, E Ingerman, J Nunnari, JE Hinshaw
Nature structural & molecular biology 18 (1), 20, 2011
A pseudoatomic model of the dynamin polymer identifies a hydrolysis-dependent powerstroke
JS Chappie, JA Mears, S Fang, M Leonard, SL Schmid, RA Milligan, ...
Cell 147 (1), 209-222, 2011
Lipid-regulated sterol transfer between closely apposed membranes by oxysterol-binding protein homologues
TA Schulz, MG Choi, S Raychaudhuri, JA Mears, R Ghirlando, ...
Journal of Cell Biology 187 (6), 889-903, 2009
Modeling a minimal ribosome based on comparative sequence analysis
JA Mears, JJ Cannone, SM Stagg, RR Gutell, RK Agrawal, SC Harvey
Journal of molecular biology 321 (2), 215-234, 2002
Structural insights into oligomerization and mitochondrial remodelling of dynamin 1‐like protein
C Fröhlich, S Grabiger, D Schwefel, K Faelber, E Rosenbaum, J Mears, ...
The EMBO journal 32 (9), 1280-1292, 2013
A corkscrew model for dynamin constriction
JA Mears, P Ray, JE Hinshaw
Structure 15 (10), 1190-1202, 2007
A structural model for the large subunit of the mammalian mitochondrial ribosome
JA Mears, MR Sharma, RR Gutell, AS McCook, PE Richardson, ...
Journal of molecular biology 358 (1), 193-212, 2006
A dimeric equilibrium intermediate nucleates Drp1 reassembly on mitochondrial membranes for fission
PJ Macdonald, N Stepanyants, N Mehrotra, JA Mears, X Qi, H Sesaki, ...
Molecular biology of the cell 25 (12), 1905-1915, 2014
Cardiolipin's propensity for phase transition and its reorganization by dynamin-related protein 1 form a basis for mitochondrial membrane fission
N Stepanyants, PJ Macdonald, CA Francy, JA Mears, X Qi, ...
Molecular biology of the cell 26 (17), 3104-3116, 2015
The mechanoenzymatic core of dynamin-related protein 1 comprises the minimal machinery required for membrane constriction
CA Francy, FJD Alvarez, L Zhou, R Ramachandran, JA Mears
Journal of Biological Chemistry 290 (18), 11692-11703, 2015
Distinct splice variants of dynamin-related protein 1 differentially utilize mitochondrial fission factor as an effector of cooperative GTPase activity
PJ Macdonald, CA Francy, N Stepanyants, L Lehman, A Baglio, JA Mears, ...
Journal of Biological Chemistry 291 (1), 493-507, 2016
A structural model for the assembly of the 30 S subunit of the ribosome
SM Stagg, JA Mears, SC Harvey
Journal of molecular biology 328 (1), 49-61, 2003
Dynamin-related protein 1 oligomerization in solution impairs functional interactions with membrane-anchored mitochondrial fission factor
RW Clinton, CA Francy, R Ramachandran, X Qi, JA Mears
Journal of Biological Chemistry 291 (1), 478-492, 2016
Cryo-EM studies of Drp1 reveal cardiolipin interactions that activate the helical oligomer
CA Francy, RW Clinton, C Fröhlich, C Murphy, JA Mears
Scientific reports 7 (1), 1-12, 2017
Cryo-electron microscopy structure of the 30S subunit in complex with the YjeQ biogenesis factor
A Jomaa, G Stewart, JA Mears, I Kireeva, ED Brown, J Ortega
Rna 17 (11), 2026-2038, 2011
Visualization of dynamins
JA Mears, JE Hinshaw
Methods in cell biology 88, 237-256, 2008
Using cross-links to study ribosomal dynamics
VI Ivanov, JA Mears
Journal of Biomolecular Structure and Dynamics 21 (6), 691-698, 2004
Morphological pathways of mitochondrial division
B Tandler, CL Hoppel, JA Mears
Antioxidants 7 (2), 30, 2018
Steric interference from intrinsically disordered regions controls dynamin-related protein 1 self-assembly during mitochondrial fission
B Lu, B Kennedy, RW Clinton, EJ Wang, D McHugh, N Stepanyants, ...
Scientific reports 8 (1), 1-21, 2018
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