Lenan Zhuang
Lenan Zhuang
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H3K4 mono-and di-methyltransferase MLL4 is required for enhancer activation during cell differentiation
JE Lee, C Wang, S Xu, YW Cho, L Wang, X Feng, A Baldridge, V Sartorelli, ...
elife 2, e01503, 2013
Innate and adaptive lymphocytes sequentially shape the gut microbiota and lipid metabolism
K Mao, AP Baptista, S Tamoutounour, L Zhuang, N Bouladoux, AJ Martins, ...
Nature 554 (7691), 255-259, 2018
Enhancer priming by H3K4 methyltransferase MLL4 controls cell fate transition
C Wang, JE Lee, B Lai, TS Macfarlan, S Xu, L Zhuang, C Liu, W Peng, ...
Proceedings of the National Academy of Sciences 113 (42), 11871-11876, 2016
UTX demethylase activity is required for satellite cell–mediated muscle regeneration
H Faralli, C Wang, K Nakka, A Benyoucef, S Sebastian, L Zhuang, A Chu, ...
The Journal of clinical investigation 126 (4), 1555-1565, 2016
Depletion of Nsd2-mediated histone H3K36 methylation impairs adipose tissue development and function
L Zhuang, Y Jang, YK Park, JE Lee, S Jain, E Froimchuk, A Broun, C Liu, ...
Nature Communications 9 (1), 1796, 2018
H3. 3K4M destabilizes enhancer H3K4 methyltransferases MLL3/MLL4 and impairs adipose tissue development
Y Jang, A Broun, C Wang, YK Park, L Zhuang, JE Lee, E Froimchuk, C Liu, ...
Nucleic Acids Research 47 (2), 607-620, 2019
H3K4 methyltransferase activity is required for MLL4 protein stability
Y Jang, C Wang, L Zhuang, C Liu, K Ge
Journal of molecular biology 429 (13), 2046-2054, 2017
Gcn5 and PCAF negatively regulate interferon‐β production through HAT‐independent inhibition of TBK 1
Q Jin, L Zhuang, B Lai, C Wang, W Li, B Dolan, Y Lu, Z Wang, K Zhao, ...
EMBO reports 15 (11), 1192-1201, 2014
Multifunctional elastomer cardiac patches for preventing left ventricle remodeling after myocardial infarction in vivo
Y Yao, A Li, S Wang, Y Lu, J Xie, H Zhang, D Zhang, J Ding, Z Wang, C Tu, ...
Biomaterials 282, 121382, 2022
β-Arrestin-1 protein represses diet-induced obesity
L Zhuang, W Hu, M Zhang, S Xin, W Jia, J Zhao, G Pei
Journal of Biological Chemistry 286 (32), 28396-28402, 2011
β-arrestin-1 protein represses adipogenesis and inflammatory responses through its interaction with peroxisome proliferator-activated receptor-γ (PPARγ)
L Zhuang, W Hu, S Xin, J Zhao, G Pei
Journal of Biological Chemistry 286 (32), 28403-28413, 2011
m6A methylation promotes white‐to‐beige fat transition by facilitating Hif1a translation
R Wu, Y Chen, Y Liu, L Zhuang, W Chen, B Zeng, X Liao, G Guo, Y Wang, ...
EMBO reports 22 (11), e52348, 2021
Coronaviruses Nsp5 antagonizes porcine gasdermin D-mediated pyroptosis by cleaving pore-forming p30 fragment
F Shi, Q Lv, T Wang, J Xu, W Xu, Y Shi, X Fu, T Yang, Y Yang, L Zhuang, ...
MBio 13 (1), e02739-21, 2022
Ultrastructural and proteomic profiling of mitochondria-associated endoplasmic reticulum membranes reveal aging signatures in striated muscle
X Lu, Y Gong, W Hu, Y Mao, T Wang, Z Sun, X Su, G Fu, Y Wang, D Lai
Cell Death & Disease 13 (4), 296, 2022
Integrated bioinformatics analysis reveals marker genes and potential therapeutic targets for pulmonary arterial hypertension
A Li, J He, Z Zhang, S Jiang, Y Gao, Y Pan, H Wang, L Zhuang
Genes 12 (9), 1339, 2021
A honeybee stinger-inspired self-interlocking microneedle patch and its application in myocardial infarction treatment
Y Lu, T Ren, H Zhang, Q Jin, L Shen, M Shan, X Zhao, Q Chen, H Dai, ...
Acta Biomaterialia 153, 386-398, 2022
Recombinant HcGAPDH Protein Expressed on Probiotic Bacillus subtilis Spores Protects Sheep from Haemonchus contortus Infection by Inducing both Humoral …
Y Yang, G Zhang, J Wu, X Chen, D Tong, Y Yang, H Shi, C Yao, L Zhuang, ...
Msystems 5 (3), 10.1128/msystems. 00239-20, 2020
Predicting the prognosis of patients in the coronary care unit: a novel multi-category machine learning model using Xgboost
X Wang, T Zhu, M Xia, Y Liu, Y Wang, X Wang, L Zhuang, D Zhong, J Zhu, ...
Frontiers in Cardiovascular Medicine 9, 764629, 2022
Identification of underlying hub genes associated with hypertrophic cardiomyopathy by integrated bioinformatics analysis
Z Ma, X Wang, Q Lv, Y Gong, M Xia, L Zhuang, X Lu, Y Yang, W Zhang, ...
Pharmacogenomics and Personalized Medicine, 823-837, 2021
Secreted MG53 from striated muscle impairs systemic insulin sensitivity
L Zhuang, R Bassel-Duby, EN Olson
Circulation 139 (7), 915-917, 2019
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