Lars Olsen

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Flemming Steen JørgensenProfessor, Department of Drug Design and Pharmacology, University of CopenhagenVerifierad e-postadress på sund.ku.dk
Patrik RydbergAssociate Director, Computational Chemmistry, Optibrium Ltd.Verifierad e-postadress på optibrium.com
Michael GajhedeProfessor i proteinkrystallografi, Københavns UniversitetVerifierad e-postadress på sund.ku.dk
Lars HemmingsenDepartment of Chemistry, University of CopenhagenVerifierad e-postadress på chem.ku.dk
Anders Skov KristensenUniversity of CopenhagenVerifierad e-postadress på sund.ku.dk
Vasanthanathan PoongavanamSenior Researcher, Uppsala UniversityVerifierad e-postadress på kemi.uu.se
Kasper B. HansenAssociate Professor, University of MontanaVerifierad e-postadress på mso.umt.edu
Kristian StrømgaardProfessor i kemisk biologi, Københavns UniversitetVerifierad e-postadress på sund.ku.dk
Silvia BonomoAstraZenecaVerifierad e-postadress på astrazeneca.com
Jesper L. KristensenUniversity of CopenhagenVerifierad e-postadress på sund.ku.dk
Marco van de WeertAssociate Professor in Biologics formulation, University of CopenhagenVerifierad e-postadress på sund.ku.dk
Curt BrenemanDean of Science, Professor of Chemistry & Chemical Biology, Rensselaer Polytechnic InstituteVerifierad e-postadress på rpi.edu
Rasmus Prætorius ClausenUniversity of CopenhagenVerifierad e-postadress på sund.ku.dk
osman mirzaAssociate professor in Medicinal chemistryVerifierad e-postadress på sund.ku.dk
Kurt V. MikkelsenProfessor of Theoretical Chemistry, Department of Chemistry, University of CopenhagenVerifierad e-postadress på chem.ku.dk
Carsten Uhd NielsenDepartment of Physics, Chemistry and Pharmacy, Faculty of Sciences, University of Southern DenmarkVerifierad e-postadress på sdu.dk
Bente SteffansenProfessor in Pharmaceutical Sciences, University of Southern DenmarkVerifierad e-postadress på sdu.dk
Per-Ola NorrbyPrincipal Scientist, AstraZenecaVerifierad e-postadress på astrazeneca.com
Stephan P. A. SauerProfessor, Department of Chemistry, University of CopenhagenVerifierad e-postadress på kiku.dk
Birger BrodinProfessor, CNS drug delivery, University of CopenhagenVerifierad e-postadress på sund.ku.dk

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Lars Olsen

Department of Drug Design and Pharmacology, University of Copenhagen

Verifierad e-postadress på novozymes.com

Cytochrome P450 Histone Demethylase Ionotropic Glutamate Receptors SMARTCyp thermodynamics


Titel Sortera efter citat Sortera efter år Sortera efter titel	Citeras av Citeras av	År
SMARTCyp: a 2D method for prediction of cytochrome P450-mediated drug metabolism P Rydberg, DE Gloriam, J Zaretzki, C Breneman, L Olsen ACS medicinal chemistry letters 1 (3), 96-100, 2010	316	2010
Study on the binding of Thioflavin T to β-sheet-rich and non-β-sheet cavities M Groenning, L Olsen, M van de Weert, JM Flink, S Frokjaer, ... Journal of structural biology 158 (3), 358-369, 2007	312	2007
5-Carboxy-8-hydroxyquinoline is a broad spectrum 2-oxoglutarate oxygenase inhibitor which causes iron translocation RJ Hopkinson, A Tumber, C Yapp, R Chowdhury, WS Aik, KH Che, XS Li, ... Chemical science 4 (8), 3110-3117, 2013	179	2013
Ionotropic glutamate-like receptor δ2 binds D-serine and glycine P Naur, KB Hansen, AS Kristensen, SM Dravid, DS Pickering, L Olsen, ... Proceedings of the National Academy of Sciences 104 (35), 14116-14121, 2007	174	2007
The SMARTCyp cytochrome P450 metabolism prediction server P Rydberg, DE Gloriam, L Olsen Bioinformatics 26 (23), 2988-2989, 2010	165	2010
Prediction of activation energies for hydrogen abstraction by cytochrome P450 L Olsen, P Rydberg, TH Rod, U Ryde Journal of medicinal chemistry 49 (22), 6489-6499, 2006	141	2006
Location of the antidepressant binding site in the serotonin transporter J Andersen, O Taboureau, KB Hansen, L Olsen, J Egebjerg, ... Journal of Biological Chemistry 284 (15), 10276-10284, 2009	128	2009
Thioflavin T hydroxylation at basic pH and its effect on amyloid fibril detection V Foderà, M Groenning, V Vetri, F Librizzi, S Spagnolo, C Cornett, L Olsen, ... The Journal of Physical Chemistry B 112 (47), 15174-15181, 2008	127	2008
Quantum chemical geometry optimizations in proteins using crystallographic raw data U Ryde, L Olsen, K Nilsson Journal of computational chemistry 23 (11), 1058-1070, 2002	126	2002
Classification of cytochrome P450 1A2 inhibitors and noninhibitors by machine learning techniques P Vasanthanathan, O Taboureau, C Oostenbrink, NPE Vermeulen, ... Drug Metabolism and Disposition 37 (3), 658-664, 2009	121	2009
Prediction of cytochrome P450 mediated metabolism L Olsen, C Oostenbrink, FS Jørgensen Advanced drug delivery reviews 86, 61-71, 2015	116	2015
Mutational mapping and modeling of the binding site for (S)-citalopram in the human serotonin transporter J Andersen, L Olsen, KB Hansen, O Taboureau, FS Jørgensen, ... Journal of Biological Chemistry 285 (3), 2051-2063, 2010	109	2010
Sulfoxide, sulfur, and nitrogen oxidation and dealkylation by cytochrome P450 P Rydberg, U Ryde, L Olsen Journal of chemical theory and computation 4 (8), 1369-1377, 2008	101	2008
RS-Predictor models augmented with SMARTCyp reactivities: robust metabolic regioselectivity predictions for nine CYP isozymes J Zaretzki, P Rydberg, C Bergeron, KP Bennett, L Olsen, CM Breneman Journal of chemical information and modeling 52 (6), 1637-1659, 2012	91	2012
Studies of H3K4me3 demethylation by KDM5B/Jarid1B/PLU1 reveals strong substrate recognition in vitro and identifies 2,4‐pyridine‐dicarboxylic acid as an in vitro and … LH Kristensen, AL Nielsen, C Helgstrand, M Lees, P Cloos, JS Kastrup, ... The FEBS journal 279 (11), 1905-1914, 2012	88	2012
Virtual screening and prediction of site of metabolism for cytochrome P450 1A2 ligands P Vasanthanathan, J Hritz, O Taboureau, L Olsen, F Steen Jørgensen, ... Journal of chemical information and modeling 49 (1), 43-52, 2009	88	2009
SMARTCyp 3.0: enhanced cytochrome P450 site-of-metabolism prediction server L Olsen, M Montefiori, KP Tran, FS Jørgensen Bioinformatics 35 (17), 3174-3175, 2019	78	2019
Evaluation of carbohydrate molecular mechanical force fields by quantum mechanical calculations L Hemmingsen, DE Madsen, AL Esbensen, L Olsen, SB Engelsen Carbohydrate research 339 (5), 937-948, 2004	78	2004
New leads of metallo-β-lactamase inhibitors from structure-based pharmacophore design L Olsen, S Jost, HW Adolph, I Pettersson, L Hemmingsen, FS Jørgensen Bioorganic & medicinal chemistry 14 (8), 2627-2635, 2006	71	2006
Design and synthesis of highly potent and plasma-stable dimeric inhibitors of the PSD-95-NMDA receptor interaction A Bach, CN Chi, GF Pang, L Olsen, AS Kristensen, P Jemth, ... Angewandte Chemie International Edition 48 (51), 9685-9689, 2009	69	2009

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