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Daniel Lindén, PhD, Associate Professor
Daniel Lindén, PhD, Associate Professor
AstraZeneca CVMD IMED Bioscience Diabetes
Verifierad e-postadress på astrazeneca.com
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Opposing effects of adiponectin receptors 1 and 2 on energy metabolism
M Bjursell, A Ahnmark, M Bohlooly-Y, L William-Olsson, M Rhedin, ...
Diabetes 56 (3), 583-593, 2007
3502007
Adipocyte differentiation-related protein promotes fatty acid storage in cytosolic triglycerides and inhibits secretion of very low–density lipoproteins
B Magnusson, L Asp, P Boström, M Ruiz, P Stillemark-Billton, D Lindén, ...
Arteriosclerosis, thrombosis, and vascular biology 26 (7), 1566-1571, 2006
1992006
Pnpla3 silencing with antisense oligonucleotides ameliorates nonalcoholic steatohepatitis and fibrosis in Pnpla3 I148M knock-in mice
D Lindén, A Ahnmark, P Pingitore, E Ciociola, I Ahlstedt, AC Andréasson, ...
Molecular metabolism 22, 49-61, 2019
1792019
Selective inhibition of FOXO1 activator/repressor balance modulates hepatic glucose handling
F Langlet, RA Haeusler, D Lindén, E Ericson, T Norris, A Johansson, ...
Cell 171 (4), 824-835. e18, 2017
1722017
Activation of peroxisome proliferator-activated receptor α increases the expression and activity of microsomal triglyceride transfer protein in the liver
C Améen, U Edvardsson, A Ljungberg, L Asp, P Åkerblad, A Tuneld, ...
Journal of Biological Chemistry 280 (2), 1224-1229, 2005
1582005
Sex difference in hepatic peroxisome proliferator-activated receptor α expression: influence of pituitary and gonadal hormones
M Jalouli, L Carlsson, C Améen, D Lindén, A Ljungberg, L Michalik, ...
Endocrinology 144 (1), 101-109, 2003
1392003
the emerging role of genetics in precision medicine for patients with non‐alcoholic steatohepatitis
B Carlsson, D Lindén, G Brolén, M Liljeblad, M Bjursell, S Romeo, ...
Alimentary pharmacology & therapeutics 51 (12), 1305-1320, 2020
1382020
Liver‐directed overexpression of mitochondrial glycerol‐3‐phosphate acyltransferase results in hepatic steatosis, increased triacylglycerol secretion and reduced fatty acid …
D Lindén, L William‐Olsson, A Ahnmark, K Ekroos, C Hallberg, ...
The FASEB journal 20 (3), 434-443, 2006
1382006
PPARα activation increases triglyceride mass and adipose differentiation-related protein in hepatocytes
U Edvardsson, A Ljungberg, D Lindén, L William-Olsson, ...
Journal of lipid research 47 (2), 329-340, 2006
1142006
Overexpression of mitochondrial GPAT in rat hepatocytes leads to decreased fatty acid oxidation and increased glycerolipid biosynthesis
D Lindén, L William-Olsson, M Rhedin, AK Asztély, JC Clapham, ...
Journal of lipid research 45 (7), 1279-1288, 2004
1122004
Human multilineage 3D spheroids as a model of liver steatosis and fibrosis
P Pingitore, K Sasidharan, M Ekstrand, S Prill, D Lindén, S Romeo
International journal of molecular sciences 20 (7), 1629, 2019
1092019
Influence of peroxisome proliferator-activated receptor α agonists on the intracellular turnover and secretion of apolipoprotein (Apo) B-100 and ApoB-48
D Lindén, K Lindberg, J Oscarsson, C Claesson, L Asp, L Li, ...
Journal of Biological Chemistry 277 (25), 23044-23053, 2002
1042002
The TM6SF2 E167K genetic variant induces lipid biosynthesis and reduces apolipoprotein B secretion in human hepatic 3D spheroids
S Prill, A Caddeo, G Baselli, O Jamialahmadi, P Dongiovanni, R Rametta, ...
Scientific reports 9 (1), 11585, 2019
1002019
An oral antisense oligonucleotide for PCSK9 inhibition
P Gennemark, K Walter, N Clemmensen, D Rekić, CAM Nilsson, ...
Science Translational Medicine 13 (593), eabe9117, 2021
882021
Growth hormone overexpression in the central nervous system results in hyperphagia-induced obesity associated with insulin resistance and dyslipidemia
M Bohlooly-Y, B Olsson, CEG Bruder, D Lindén, K Sjogren, M Bjursell, ...
Diabetes 54 (1), 51-62, 2005
862005
PPARα deficiency increases secretion and serum levels of apolipoprotein B-containing lipoproteins
D Lindén, M Alsterholm, H Wennbo, J Oscarsson
Journal of Lipid Research 42 (11), 1831-1840, 2001
842001
In vivo genome and base editing of a human PCSK9 knock-in hypercholesterolemic mouse model
A Carreras, LS Pane, R Nitsch, K Madeyski-Bengtson, M Porritt, ...
BMC biology 17, 1-14, 2019
812019
Ageing Fxr deficient mice develop increased energy expenditure, improved glucose control and liver damage resembling NASH
M Bjursell, M Wedin, T Admyre, M Hermansson, G Böttcher, M Göransson, ...
PloS one 8 (5), e64721, 2013
792013
Long-term growth hormone excess induces marked alterations in lipoprotein metabolism in mice
F Frick, M Bohlooly-Y, D Lindén, B Olsson, J Törnell, S Edén, ...
American Journal of Physiology-Endocrinology and Metabolism 281 (6), E1230-E1239, 2001
742001
The beneficial effects of n-3 polyunsaturated fatty acids on diet induced obesity and impaired glucose control do not require Gpr120
M Bjursell, X Xu, T Admyre, G Böttcher, S Lundin, R Nilsson, VM Stone, ...
PloS one 9 (12), e114942, 2014
722014
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Artiklar 1–20