Antibody production: polyclonal-derived biotherapeutics C Newcombe, AR Newcombe Journal of Chromatography B 848 (1), 2-7, 2007 | 118 | 2007 |
Optimised affinity purification of polyclonal antibodies from hyper immunised ovine serum using a synthetic Protein A adsorbent, MAbsorbent® A2P AR Newcombe, C Cresswell, S Davies, K Watson, G Harris, K O’Donovan, ... Journal of Chromatography B 814 (2), 209-215, 2005 | 96 | 2005 |
Biopharmaceutical production: Applications of surface plasmon resonance biosensors P Thillaivinayagalingam, J Gommeaux, M McLoughlin, D Collins, ... Journal of Chromatography B 878 (2), 149-153, 2010 | 74 | 2010 |
How implementation of quality by design and advances in biochemical engineering are enabling efficient bioprocess development and manufacture S Chhatre, SS Farid, J Coffman, P Bird, AR Newcombe, ... Journal of Chemical Technology & Biotechnology 86 (9), 1125-1129, 2011 | 42 | 2011 |
Purification of Tubulin from the Fission Yeast Schizosaccharomyces pombe DR Drummond, S Kain, A Newcombe, C Hoey, M Katsuki, RA Cross Microtubule Dynamics: Methods and Protocols, 29-55, 2011 | 32 | 2011 |
The interaction between rac1 and its guanine nucleotide dissociation inhibitor (GDI), monitored by a single fluorescent coumarin attached to GDI AR Newcombe, RW Stockley, JL Hunter, MR Webb Biochemistry 38 (21), 6879-6886, 1999 | 31 | 1999 |
Purification of antibodies using the synthetic affinity ligand absorbent MAbsorbent A2P S Chhatre, NJ Titchener-Hooker, AR Newcombe, E Keshavarz–Moore Nature Protocols 2 (7), 1763-1769, 2007 | 29 | 2007 |
Global sensitivity analysis for the determination of parameter importance in bio‐manufacturing processes S Chhatre, R Francis, AR Newcombe, Y Zhou, N Titchener‐Hooker, ... Biotechnology and applied biochemistry 51 (2), 79-90, 2008 | 21 | 2008 |
Detection and quantification of affinity ligand leaching and specific antibody fragment concentration within chromatographic fractions using surface plasmon resonance P Thillaivinayagalingam, AR Newcombe, K O'Donovan, R Francis, ... Biotechnology and applied biochemistry 48 (4), 179-188, 2007 | 19 | 2007 |
Characterisation of an industrial affinity process used in the manufacturing of digoxin-specific polyclonal Fab fragments P Thillaivinayagalingam, K O’Donovan, AR Newcombe, ... Journal of Chromatography B 848 (1), 88-96, 2007 | 18 | 2007 |
A decision-support model for evaluating changes in biopharmaceutical manufacturing processes S Chhatre, R Francis, K O’Donovan, NJ Titchener-Hooker, AR Newcombe, ... Bioprocess and biosystems engineering 30, 1-11, 2007 | 17 | 2007 |
Optimal conditions for the papain digestion of polyclonal ovine IgG for the production of biotherapeutic Fab fragments C Cresswell, AR Newcombe, S Davies, I Macpherson, P Nelson, ... Biotechnology and applied biochemistry 42 (2), 163-168, 2005 | 17 | 2005 |
Evaluation of a biosensor assay to quantify polyclonal IgG in ovine serum used for the production of biotherapeutic antibody fragments AR Newcombe, C Cresswell, S Davies, F Pearce, K O’Donovan, ... Process biochemistry 41 (4), 842-847, 2006 | 16 | 2006 |
The integrated simulation and assessment of the impacts of process change in biotherapeutic antibody production S Chhatre, C Jones, R Francis, K O'Donovan, N Titchener‐Hooker, ... Biotechnology progress 22 (6), 1612-1620, 2006 | 16 | 2006 |
Revisiting protein A chromatography P Thillaivinayagalingam, K Reidy, A Lindeberg, AR Newcombe BioProcess International 10 (3), 2012 | 14 | 2012 |
Global sensitivity analysis for the determination of parameter importance in the chromatographic purification of polyclonal antibodies S Chhatre, R Francis, AR Newcombe, Y Zhou, N Titchener‐Hooker, ... Journal of Chemical Technology & Biotechnology: International Research in …, 2008 | 12 | 2008 |
Evaluation of a novel agarose-based synthetic ligand adsorbent for the recovery of antibodies from ovine serum S Chhatre, R Francis, NJ Titchener-Hooker, AR Newcombe, ... Journal of Chromatography B 860 (2), 209-217, 2007 | 12 | 2007 |
Decision‐support software for the industrial‐scale chromatographic purification of antibodies S Chhatre, P Thillaivinayagalingam, R Francis, NJ Titchener‐Hooker, ... Biotechnology progress 23 (4), 888-894, 2007 | 11 | 2007 |
A prototype software methodology for the rapid evaluation of biomanufacturing process options S Chhatre, R Francis, K O'donovan, NJ Titchener‐Hooker, AR Newcombe, ... Biotechnology and applied biochemistry 48 (2), 65-78, 2007 | 8 | 2007 |
Validation of intermediate hold times P Thillaivinayagalingam, AR Newcombe BioProcess International 9 (4), 52-57, 2011 | 2 | 2011 |