| Genomic and drug target evaluation of 90 cardiovascular proteins in 30,931 individuals folkersen nature metabolism 2 (10), 1135-1148, 2020 | 357 | 2020 |
| Effect of a second-generation α2δ ligand (pregabalin) on visceral sensation in hypersensitive patients with irritable bowel syndrome LA Houghton, C Fell, PJ Whorwell, I Jones, DP Sudworth, JD Gale Gut 56 (9), 1218-1225, 2007 | 235 | 2007 |
| GR205171: a novel antagonist with high affinity for the tachykinin NK1 receptor, and potent broad-spectrum anti-emetic activity CJ Gardner, DR Armour, DT Beattie, JD Gale, AB Hawcock, GJ Kilpatrick, ... Regulatory peptides 65 (1), 45-53, 1996 | 180 | 1996 |
| GR113808: a novel, selective antagonist with high affinity at the 5‐HT4 receptor JD Gale, CJ Grossman, JWF Whitehead, AW Oxford, KT Bunce, ... British journal of pharmacology 111 (1), 332-338, 1994 | 148 | 1994 |
| The broad-spectrum anti-emetic activity of the novel non-peptide tachykinin NK1 receptor antagonist GR203040. CJ Gardner, DJ Twissell, TJ Dale, JD Gale, CC Jordan, GJ Kilpatrick, ... British journal of pharmacology 116 (8), 3158, 1995 | 140 | 1995 |
| Online high-flow peptide immunoaffinity enrichment and nanoflow LC-MS/MS: assay development for total salivary pepsin/pepsinogen H Neubert, J Gale, D Muirhead Clinical chemistry 56 (9), 1413-1423, 2010 | 100 | 2010 |
| Digital image analysis of collagen assessment of progression of fibrosis in recurrent HCV after liver transplantation P Manousou, AK Burroughs, ET Sochatzis, G Isgro, A Hall, A Green, ... Journal of hepatology 58 (5), 962-968, 2013 | 63 | 2013 |
| Phosphodiesterase type 5 inhibition reduces albuminuria in subjects with overt diabetic nephropathy W Scheele, S Diamond, J Gale, V Clerin, N Tamimi, V Le, R Walley, ... Journal of the American Society of Nephrology 27 (11), 3459-3468, 2016 | 62 | 2016 |
| Advantages of a wholly Bayesian approach to assessing efficacy in early drug development: a case study RJ Walley, CL Smith, JD Gale, P Woodward Pharmaceutical Statistics 14 (3), 205-215, 2015 | 61 | 2015 |
| Alpha 2 Delta (α2δ) Ligands, Gabapentin and Pregabalin: What is the Evidence for Potential Use of These Ligands in Irritable Bowel Syndrome JD Gale, LA Houghton Frontiers in pharmacology 2, 28, 2011 | 58 | 2011 |
| Towards understanding the aetiology and pathophysiology of the emetic reflex: novel approaches to antiemetic drugs C Bountra, JD Gale, CJ Gardner, CC Jordan, GJ Kilpatrick, DJ Twissell, ... ONCOLOGY-BASEL- 53, 102-109, 1996 | 57 | 1996 |
| An experimental study of viscero-visceral hyperalgesia using an ultrasound-based multimodal sensory testing approach JB Frøkjær, SD Andersen, J Gale, L Arendt-Nielsen, H Gregersen, ... Pain 119 (1-3), 191-200, 2005 | 56 | 2005 |
| 5-HT3 and 5-HT4 receptors in terminal regions of the mesolimbic system GJ Kilpatrick, RM Hagan, JD Gale Behavioural brain research 73 (1-2), 11-13, 1995 | 54 | 1995 |
| The pharmacological properties of the novel selective 5‐HT3 receptor antagonist, alosetron, and its effects on normal and perturbed small intestinal transit in the … CLAYTON, SARGENT, BUTLER, GALE, MAXWELL, HUNT, BARRETT, ... Neurogastroenterology & Motility 11 (3), 207-217, 1999 | 50 | 1999 |
| Macroscopic, microscopic and biochemical characterisation of spontaneous colitis in a transgenic mouse, deficient in the multiple drug resistance 1a gene KH Banner, C Cattaneo, JLL Net, A Popovic, D Collins, JD Gale British journal of pharmacology 143 (5), 590-598, 2004 | 49 | 2004 |
| The use of novel promotility and prosecretory agents for the treatment of chronic idiopathic constipation and irritable bowel syndrome with constipation JD Gale Advances in therapy 26, 519-530, 2009 | 46 | 2009 |
| Central pain mechanisms following combined acid and capsaicin perfusion of the human oesophagus C Brock, T Andresen, JB Frøkjær, J Gale, AE Olesen, L Arendt-Nielsen, ... European Journal of Pain 14 (3), 273-281, 2010 | 45 | 2010 |
| Multimodal sensory testing of the rectum and rectosigmoid: development and reproducibility of a new method C Brock, TD Nissen, FH Gravesen, JB Frøkjaer, H Omar, J Gale, ... Neurogastroenterology & Motility 20 (8), 908-918, 2008 | 45 | 2008 |
| Effect of PF-04634817, an oral CCR2/5 chemokine receptor antagonist, on albuminuria in adults with overt diabetic nephropathy JD Gale, S Gilbert, S Blumenthal, T Elliott, PE Pergola, K Goteti, ... Kidney international reports 3 (6), 1316-1327, 2018 | 44 | 2018 |
| A selective, high affinity 5‐HT2B receptor antagonist inhibits visceral hypersensitivity in rats K Ohashi‐Doi, D Himaki, K Nagao, M Kawai, JD Gale, JB Furness, ... Neurogastroenterology & Motility 22 (2), e69-e76, 2010 | 42 | 2010 |
