| Reverse transcriptase encoded by a human transposable element SL Mathias, AF Scott, HH Kazazian Jr, JD Boeke, A Gabriel Science 254 (5039), 1808-1810, 1991 | 897 | 1991 |
| Isolation of an active human transposable element BA Dombroski, SL Mathias, E Nanthakumar, AF Scott, HH Kazazian Jr Science 254 (5039), 1805-1808, 1991 | 540 | 1991 |
| Unexplored therapeutic opportunities in the human genome TI Oprea, CG Bologa, S Brunak, A Campbell, GN Gan, A Gaulton, ... Nature reviews Drug discovery 17 (5), 317-332, 2018 | 398 | 2018 |
| DrugCentral: online drug compendium O Ursu, J Holmes, J Knockel, CG Bologa, JJ Yang, SL Mathias, SJ Nelson, ... Nucleic acids research, gkw993, 2016 | 295 | 2016 |
| Pharos: collating protein information to shed light on the druggable genome DT Nguyen, S Mathias, C Bologa, S Brunak, N Fernandez, A Gaulton, ... Nucleic acids research 45 (D1), D995-D1002, 2017 | 270 | 2017 |
| DrugCentral 2018: an update O Ursu, J Holmes, CG Bologa, JJ Yang, SL Mathias, V Stathias, ... Nucleic acids research 47 (D1), D963-D970, 2019 | 135 | 2019 |
| TCRD and Pharos 2021: mining the human proteome for disease biology TK Sheils, SL Mathias, KJ Kelleher, VB Siramshetty, DT Nguyen, ... Nucleic Acids Research 49 (D1), D1334-D1346, 2021 | 130 | 2021 |
| Associating drugs, targets and clinical outcomes into an integrated network affords a new platform for computer‐aided drug repurposing TI Oprea, SK Nielsen, O Ursu, JJ Yang, O Taboureau, SL Mathias, ... Molecular informatics 30 (2‐3), 100-111, 2011 | 126 | 2011 |
| An in vivo assay for the reverse transcriptase of human retrotransposon L1 in Saccharomyces cerevisiae BA Dombroski, Q Feng, SL Mathias, DM Sassaman, AF Scott, ... Molecular and cellular biology, 1994 | 126 | 1994 |
| A 20.7 kb deletion within the factor VIII gene associated with LINE-1 element insertion N Van de Water, R Williams, P Ockelford, P Browett Thrombosis and haemostasis 79 (05), 938-942, 1998 | 91 | 1998 |
| Characterization of a nondeleterious L1 insertion in an intron of the human factor VIII gene and further evidence of open reading frames in functional L1 elements P Woods-Samuels, C Wong, SL Mathias, AF Scott, HH Kazazian Jr, ... Genomics 4 (3), 290-296, 1989 | 82 | 1989 |
| Drug target ontology to classify and integrate drug discovery data Y Lin, S Mehta, H Küçük-McGinty, JP Turner, D Vidovic, M Forlin, A Koleti, ... Journal of biomedical semantics 8, 1-16, 2017 | 78 | 2017 |
| Pharos 2023: an integrated resource for the understudied human proteome KJ Kelleher, TK Sheils, SL Mathias, JJ Yang, VT Metzger, VB Siramshetty, ... Nucleic acids research 51 (D1), D1405-D1416, 2023 | 46 | 2023 |
| How to illuminate the druggable genome using pharos T Sheils, SL Mathias, VB Siramshetty, G Bocci, CG Bologa, JJ Yang, ... Current protocols in bioinformatics 69 (1), e92, 2020 | 36 | 2020 |
| The CARLSBAD database: a confederated database of chemical bioactivities SL Mathias, J Hines-Kay, JJ Yang, G Zahoransky-Kohalmi, CG Bologa, ... Database 2013, bat044, 2013 | 35 | 2013 |
| TIN-X: target importance and novelty explorer DC Cannon, JJ Yang, SL Mathias, O Ursu, S Mani, A Waller, SC Schürer, ... Bioinformatics 33 (16), 2601-2603, 2017 | 32 | 2017 |
| Promoter binding proteins of an active human L1 retrotransposon SL Mathias, AF Scott Biochemical and biophysical research communications 191 (2), 625-632, 1993 | 32 | 1993 |
| Formalizing drug indications on the road to therapeutic intent SJ Nelson, TI Oprea, O Ursu, CG Bologa, A Zaveri, J Holmes, JJ Yang, ... Journal of the American Medical Informatics Association 24 (6), 1169-1172, 2017 | 11 | 2017 |
| TIGA: target illumination GWAS analytics JJ Yang, D Grissa, CG Lambert, CG Bologa, SL Mathias, A Waller, ... Bioinformatics 37 (21), 3865-3873, 2021 | 10 | 2021 |
| Compounds SL Mathias US Patent 6,069,239, 2000 | 4 | 2000 |
