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Sebastian Mikolajczak
Sebastian Mikolajczak
Novartis Institute for Tropical Diseases
Verified email at novartis.com
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Cited by
Cited by
Year
Protection against malaria at 1 year and immune correlates following PfSPZ vaccination
AS Ishizuka, KE Lyke, A DeZure, AA Berry, TL Richie, FH Mendoza, ...
Nature medicine 22 (6), 614-623, 2016
3692016
Complete Plasmodium falciparum liver-stage development in liver-chimeric mice
AM Vaughan, SA Mikolajczak, EM Wilson, M Grompe, A Kaushansky, ...
The Journal of clinical investigation 122 (10), 3618-3628, 2012
2392012
Plasmodium vivax liver stage development and hypnozoite persistence in human liver-chimeric mice
SA Mikolajczak, AM Vaughan, N Kangwanrangsan, W Roobsoong, ...
Cell host & microbe 17 (4), 526-535, 2015
2192015
Preerythrocytic, live-attenuated Plasmodium falciparum vaccine candidates by design
KM VanBuskirk, MT O'Neill, P De La Vega, AG Maier, U Krzych, J Williams, ...
Proceedings of the National Academy of Sciences 106 (31), 13004-13009, 2009
2082009
Plasmodium yoelii Sporozoites with Simultaneous Deletion of P52 and P36 Are Completely Attenuated and Confer Sterile Immunity against Infection
M Labaied, A Harupa, RF Dumpit, I Coppens, SA Mikolajczak, SHI Kappe
Infection and immunity 75 (8), 3758-3768, 2007
1862007
First-in-human evaluation of genetically attenuated Plasmodium falciparum sporozoites administered by bite of Anopheles mosquitoes to adult volunteers
M Spring, J Murphy, R Nielsen, M Dowler, JW Bennett, S Zarling, ...
Vaccine 31 (43), 4975-4983, 2013
1692013
Neuroimmunological blood brain barrier opening in experimental cerebral malaria
A Nacer, A Movila, K Baer, SA Mikolajczak, SHI Kappe, U Frevert
PLoS pathogens 8 (10), e1002982, 2012
1642012
Heme oxygenase-1 is an anti-inflammatory host factor that promotes murine plasmodium liver infection
S Epiphanio, SA Mikolajczak, LA Gonçalves, A Pamplona, S Portugal, ...
Cell host & microbe 3 (5), 331-338, 2008
1622008
A comprehensive model for assessment of liver stage therapies targeting Plasmodium vivax and Plasmodium falciparum
A Roth, SP Maher, AJ Conway, R Ubalee, V Chaumeau, C Andolina, ...
Nature communications 9 (1), 1837, 2018
1522018
In vitro culture, drug sensitivity, and transcriptome of Plasmodium vivax hypnozoites
N Gural, L Mancio-Silva, AB Miller, A Galstian, VL Butty, SS Levine, ...
Cell host & microbe 23 (3), 395-406. e4, 2018
1462018
Targeted deletion of SAP1 abolishes the expression of infectivity factors necessary for successful malaria parasite liver infection
ASI Aly, SA Mikolajczak, HS Rivera, N Camargo, V Jacobs‐Lorena, ...
Molecular microbiology 69 (1), 152-163, 2008
1252008
Complete attenuation of genetically engineered Plasmodium falciparum sporozoites in human subjects
JG Kublin, SA Mikolajczak, BK Sack, ME Fishbaugher, A Seilie, L Shelton, ...
Science translational medicine 9 (371), eaad9099, 2017
1202017
L-FABP is a critical host factor for successful malaria liver stage development
SA Mikolajczak, V Jacobs-Lorena, DC MacKellar, N Camargo, SHI Kappe
International journal for parasitology 37 (5), 483-489, 2007
1162007
Suppression of host p53 is critical for Plasmodium liver-stage infection
A Kaushansky, SY Albert, LS Austin, SA Mikolajczak, AM Vaughan, ...
Cell reports 3 (3), 630-637, 2013
1092013
A next-generation genetically attenuated Plasmodium falciparum parasite created by triple gene deletion
SA Mikolajczak, V Lakshmanan, M Fishbaugher, N Camargo, A Harupa, ...
Molecular therapy 22 (9), 1707-1715, 2014
1042014
Development of humanized mouse models to study human malaria parasite infection
AM Vaughan, SHI Kappe, A Ploss, SA Mikolajczak
Future microbiology 7 (5), 657-665, 2012
1042012
Model for In Vivo Assessment of Humoral Protection against Malaria Sporozoite Challenge by Passive Transfer of Monoclonal Antibodies and Immune Serum
BK Sack, JL Miller, AM Vaughan, A Douglass, A Kaushansky, ...
Infection and immunity 82 (2), 808-817, 2014
952014
Distinct malaria parasite sporozoites reveal transcriptional changes that cause differential tissue infection competence in the mosquito vector and mammalian host
SA Mikolajczak, H Silva-Rivera, X Peng, AS Tarun, N Camargo, ...
Molecular and cellular biology 28 (20), 6196-6207, 2008
952008
Perturbations of Plasmodium Puf2 expression and RNA‐seq of Puf2‐deficient sporozoites reveal a critical role in maintaining RNA homeostasis and parasite …
SE Lindner, SA Mikolajczak, AM Vaughan, W Moon, BR Joyce, ...
Cellular microbiology 15 (7), 1266-1283, 2013
802013
Malaria parasite liver stages render host hepatocytes susceptible to mitochondria-initiated apoptosis
A Kaushansky, PG Metzger, AN Douglass, SA Mikolajczak, ...
Cell death & disease 4 (8), e762-e762, 2013
772013
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