|A mutation in Orai1 causes immune deficiency by abrogating CRAC channel function|
S Feske, Y Gwack, M Prakriya, S Srikanth, SH Puppel, B Tanasa, ...
Nature 441 (7090), 179-185, 2006
|Orai1 is an essential pore subunit of the CRAC channel|
M Prakriya, S Feske, Y Gwack, S Srikanth, A Rao, PG Hogan
Nature 443 (7108), 230-233, 2006
|Biochemical and functional characterization of Orai proteins|
Y Gwack, S Srikanth, S Feske, F Cruz-Guilloty, M Oh-hora, DS Neems, ...
Journal of Biological Chemistry 282 (22), 16232-16243, 2007
|A genome-wide Drosophila RNAi screen identifies DYRK-family kinases as regulators of NFAT|
Y Gwack, S Sharma, J Nardone, B Tanasa, A Iuga, S Srikanth, H Okamura, ...
Nature 441 (7093), 646-650, 2006
|C-terminal domain of the hepatitis C virus NS3 protein contains an RNA helicase activity|
DW Kim, Y Gwack, JH Han, J Choe
Biochemical and biophysical research communications 215 (1), 160-166, 1995
|Dynamic assembly of TRPC1-STIM1-Orai1 ternary complex is involved in store-operated calcium influx Evidence for similarities in store-operated and calcium release-activated …|
HL Ong, KT Cheng, X Liu, BC Bandyopadhyay, BC Paria, J Soboloff, ...
Journal of Biological Chemistry 282 (12), 9105-9116, 2007
|Signalling to transcription: store-operated Ca2+ entry and NFAT activation in lymphocytes|
Y Gwack, S Feske, S Srikanth, PG Hogan, A Rao
Cell calcium 42 (2), 145-156, 2007
|Hair loss and defective T-and B-cell function in mice lacking ORAI1|
Y Gwack, S Srikanth, M Oh-Hora, PG Hogan, ED Lamperti, M Yamashita, ...
Molecular and cellular biology 28 (17), 5209-5222, 2008
|Global changes in Kaposi's sarcoma-associated virus gene expression patterns following expression of a tetracycline-inducible Rta transactivator|
H Nakamura, M Lu, Y Gwack, J Souvlis, SL Zeichner, JU Jung
Journal of virology 77 (7), 4205-4220, 2003
|A novel EF-hand protein, CRACR2A, is a cytosolic Ca 2+ sensor that stabilizes CRAC channels in T cells|
S Srikanth, HJ Jung, KD Kim, P Souda, J Whitelegge, Y Gwack
Nature cell biology 12 (5), 436-446, 2010
|Characterization of RNA binding activity and RNA helicase activity of the hepatitis C virus NS3 protein|
Y Gwack, DW Kim, JH Han, J Choe
Biochemical and biophysical research communications 225 (2), 654-659, 1996
|CREB-binding protein and histone deacetylase regulate the transcriptional activity of Kaposi's sarcoma-associated herpesvirus open reading frame 50|
Y Gwack, H Byun, S Hwang, C Lim, J Choe
Journal of virology 75 (4), 1909-1917, 2001
|Mutational analysis of the hepatitis C virus RNA helicase.|
DW Kim, J Kim, Y Gwack, JH Han, J Choe
Journal of Virology 71 (12), 9400-9409, 1997
|Latency-associated nuclear antigen of Kaposi’s sarcoma-associated herpesvirus (human herpesvirus-8) binds ATF4/CREB2 and inhibits its transcriptional activation activity|
C Lim, H Sohn, Y Gwack, J Choe
Journal of General Virology 81 (11), 2645-2652, 2000
|The ion channel TRPV1 regulates the activation and proinflammatory properties of CD4+ T cells|
S Bertin, Y Aoki-Nonaka, PR De Jong, LL Nohara, H Xu, SR Stanwood, ...
Nature immunology 15 (11), 1055-1063, 2014
|Dynamic movement of the calcium sensor STIM1 and the calcium channel Orai1 in activated T-cells: puncta and distal caps|
VA Barr, KM Bernot, S Srikanth, Y Gwack, L Balagopalan, CK Regan, ...
Molecular biology of the cell 19 (7), 2802-2817, 2008
|The transcriptional activity of cAMP response element-binding protein-binding protein is modulated by the latency associated nuclear antigen of Kaposi's sarcoma-associated …|
C Lim, Y Gwack, S Hwang, S Kim, J Choe
Journal of Biological Chemistry 276 (33), 31016-31022, 2001
|Functional dissection of latency-associated nuclear antigen 1 of Kaposi's sarcoma-associated herpesvirus involved in latent DNA replication and transcription of terminal …|
C Lim, H Sohn, D Lee, Y Gwack, J Choe
Journal of virology 76 (20), 10320-10331, 2002
|Principal role of TRAP/mediator and SWI/SNF complexes in Kaposi's sarcoma-associated herpesvirus RTA-mediated lytic reactivation|
Y Gwack, HJ Baek, H Nakamura, SH Lee, M Meisterernst, RG Roeder, ...
Molecular and cellular biology 23 (6), 2055-2067, 2003
|Junctate is a Ca2+-sensing structural component of Orai1 and stromal interaction molecule 1 (STIM1)|
S Srikanth, M Jew, KD Kim, MK Yee, J Abramson, Y Gwack
Proceedings of the National Academy of Sciences 109 (22), 8682-8687, 2012