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Chrissie K Lim
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Human DPP9 represses NLRP1 inflammasome and protects against autoinflammatory diseases via both peptidase activity and FIIND domain binding
FL Zhong, K Robinson, DET Teo, KY Tan, C Lim, CR Harapas, CH Yu, ...
Journal of Biological Chemistry 293 (49), 18864-18878, 2018
1912018
Enteroviral 3C protease activates the human NLRP1 inflammasome in airway epithelia
KS Robinson, DET Teo, KS Tan, GA Toh, HH Ong, CK Lim, K Lay, BV Au, ...
Science 370 (6521), eaay2002, 2020
1842020
The role of the IL-22/IL-22R1 axis in cancer
C Lim, R Savan
Cytokine & growth factor reviews 25 (3), 257-271, 2014
1812014
Primary human CD4+ T cells have diverse levels of membrane lipid order that correlate with their function
L Miguel, DM Owen, C Lim, C Liebig, J Evans, AI Magee, EC Jury
The Journal of Immunology 186 (6), 3505-3516, 2011
892011
ZAKα-driven ribotoxic stress response activates the human NLRP1 inflammasome
KS Robinson, GA Toh, P Rozario, R Chua, S Bauernfried, Z Sun, ...
Science 377 (6603), 328-335, 2022
672022
Interferon lambda 4 expression is suppressed by the host during viral infection
MA Hong, J Schwerk, C Lim, A Kell, A Jarret, J Pangallo, YM Loo, S Liu, ...
Journal of Experimental Medicine 213 (12), 2539-2552, 2016
612016
Human IL-22 binding protein isoforms act as a rheostat for IL-22 signaling
C Lim, MA Hong, R Savan
Science signaling 9 (447), ra95-ra95, 2016
312016
Dominant-negative NFKBIA mutation promotes IL-1β production causing hepatic disease with severe immunodeficiency
EEK Tan, R Hopkins, CK Lim, S Jamuar, C Ong, KC Thoon, MJ Koh, ...
The Journal of clinical investigation, 98882, 2020
202020
Enteroviral 3C protease activates the human NLRP1 inflammasome in airway epithelia. Science. 370: eaay2002
KS Robinson, DET Teo, KS Tan, GA Toh, HH Ong, CK Lim, K Lay, BV Au, ...
142020
Diphtheria toxin activates ribotoxic stress and NLRP1 inflammasome-driven pyroptosis
KS Robinson, GA Toh, MJ Firdaus, KC Tham, P Rozario, CK Lim, YX Toh, ...
Journal of Experimental Medicine 220 (10), e20230105, 2023
102023
Human NLRP1 is activated by ZAKɑ-driven ribotoxic stress response
KS Robinson, GA Toh, P Rozario, S Bayat, Z Sun, S Bauernfried, ...
bioRxiv, 2022.01. 24.477516, 2022
62022
Corynebacterium diphtheriae causes keratinocyte-intrinsic ribotoxic stress and NLRP1 inflammasome activation in a model of cutaneous diphtheria
KS ROBINSON, GA TOH, MJ FIRDAUS, KC THAM, P ROZARIO, C LIM, ...
bioRxiv, 2023.01. 16.524188, 2023
32023
DPP9 is an endogenous and direct inhibitor of the NLRP1 inflammasome that guards against human auto-inflammatory diseases
FL Zhong, K Robinson, C Lim, CR Harapas, CH Yu, W Xie, RM Sobota, ...
bioRxiv, 260919, 2018
12018
Natural killer cell memory precedes HLH in monozygotic twins discordant for chronic active Epstein-Barr virus disease
CK Lim, Y Zhong, R Hopkins, WX Sin, BV Au, S Narayanan, CH Huang, ...
Blood, The Journal of the American Society of Hematology 141 (17), 2151-2155, 2023
2023
Corynebacterium diphtheriaecauses keratinocyte-intrinsic ribotoxic stress and NLRP1 inflammasome activation in a model of cutaneous diphtheria
R KS, TOH GA, F MJ, T KC, P ROZARIO, C LIM, TOH YX, LAU ZH, B SC, ...
2023
Direct cleavage of human NLRP1 by enteroviral 3C protease triggers inflammasome activation in airway epithelium
KS Robinson, TK Sen, DE Thiam Teo, OH Hui, B Au, C Lim, LT Sheng, ...
bioRxiv, 2020.10. 14.325076, 2020
2020
Alternative splicing takes charge of interleukin-22 and interferon lambda 4 signaling
C Lim
Thesis Commons, 2018
2018
THE IL-22 BINDING PROTEIN ISOFORMS ARE A RHEOSTAT FOR IL-22 SIGNALING
C Lim, M Hong, R Savan
CYTOKINE 87, 73-73, 2016
2016
EVOLUTIONARY ADAPTATIONS SUPPRESS INTERFERON LAMBDA 4 EXPRESSION DURING VIRAL INFECTION
J Schwerk, M Hong, C Lim, A Kell, A Jarret, J Pangallo, YM Loo, M Gale Jr, ...
CYTOKINE 87, 80-80, 2016
2016
Interferon lambda 4 expression is suppressed by the host during viral infection.
HMA Hong MeeAe, J Schwerk, C Lim, A Kell, A Jarret, J Pangallo, ...
2016
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