Insights into E3 ligase activity revealed by a SUMO–RanGAP1–Ubc9–Nup358 complex D Reverter, CD Lima Nature 435 (7042), 687-692, 2005 | 547 | 2005 |
Specific and covalent targeting of conjugating and deconjugating enzymes of ubiquitin-like proteins J Hemelaar, A Borodovsky, BM Kessler, D Reverter, J Cook, N Kolli, ... Molecular and cellular biology 24 (1), 84-95, 2004 | 235 | 2004 |
A basis for SUMO protease specificity provided by analysis of human Senp2 and a Senp2-SUMO complex D Reverter, CD Lima Structure 12 (8), 1519-1531, 2004 | 234 | 2004 |
Structural basis for SENP2 protease interactions with SUMO precursors and conjugated substrates D Reverter, CD Lima Nature structural & molecular biology 13 (12), 1060-1068, 2006 | 170 | 2006 |
Structure of the human SENP7 catalytic domain and poly-SUMO deconjugation activities for SENP6 and SENP7 CD Lima, D Reverter Journal of Biological Chemistry 283 (46), 32045-32055, 2008 | 165 | 2008 |
Repositioning tolcapone as a potent inhibitor of transthyretin amyloidogenesis and associated cellular toxicity R Sant'Anna, P Gallego, LZ Robinson, A Pereira-Henriques, N Ferreira, ... Nature communications 7 (1), 10787, 2016 | 161 | 2016 |
A carboxypeptidase inhibitor from the medical leech Hirudo medicinalis: Isolation, sequence analysis, cDNA cloning, recombinant expression, and characterization D Reverter, J Vendrell, F Canals, J Horstmann, FX Avilés, H Fritz, ... Journal of Biological Chemistry 273 (49), 32927-32933, 1998 | 136 | 1998 |
Evidence for a two-state transition in the folding process of the activation domain of human procarboxypeptidase A2 V Villegas, A Azuaga, L Catasus, D Reverter, PL Mateo, FX Aviles, ... Biochemistry 34 (46), 15105-15110, 1995 | 124 | 1995 |
Structure of a novel leech carboxypeptidase inhibitor determined free in solution and in complex with human carboxypeptidase A2 D Reverter, C Fernández-Catalán, R Baumgartner, R Pfänder, R Huber, ... Nature structural biology 7 (4), 322-328, 2000 | 120 | 2000 |
SUMO-2 and PIAS1 modulate insoluble mutant huntingtin protein accumulation JG O’Rourke, JR Gareau, J Ochaba, W Song, T Raskó, D Reverter, J Lee, ... Cell reports 4 (2), 362-375, 2013 | 117 | 2013 |
The three‐dimensional structure of human procarboxypeptidase A2. Deciphering the basis of the inhibition, activation and intrinsic activity of the zymogen I García‐Sáez, D Reverter, J Vendrell, FX Avilés, M Coll The EMBO journal, 1997 | 110 | 1997 |
Structure of a complex between Nedd8 and the Ulp/Senp protease family member Den1 D Reverter, K Wu, TG Erdene, ZQ Pan, KD Wilkinson, CD Lima Journal of molecular biology 345 (1), 141-151, 2005 | 90 | 2005 |
Determinants of small ubiquitin-like modifier 1 (SUMO1) protein specificity, E3 ligase, and SUMO-RanGAP1 binding activities of nucleoporin RanBP2 JR Gareau, D Reverter, CD Lima Journal of Biological Chemistry 287 (7), 4740-4751, 2012 | 86 | 2012 |
RARRES3 suppresses breast cancer lung metastasis by regulating adhesion and differentiation M Morales, EJ Arenas, J Urosevic, M Guiu, E Fernández, E Planet, ... EMBO molecular medicine 6 (7), 865-881, 2014 | 84 | 2014 |
Crystal structure of human carboxypeptidase M, a membrane-bound enzyme that regulates peptide hormone activity D Reverter, K Maskos, F Tan, RA Skidgel, W Bode Journal of molecular biology 338 (2), 257-269, 2004 | 78 | 2004 |
Structural basis for possible calcium-induced activation mechanisms of calpains D Reverter, S Strobl, C Fernandez-Catalan, H Sorimachi, K Suzuki, ... Biological chemistry 382 (5), 753-766, 2001 | 75 | 2001 |
The structure of calcium-free human m-calpain: implications for calcium activation and function D Reverter, H Sorimachi, W Bode Trends in cardiovascular medicine 11 (6), 222-229, 2001 | 69 | 2001 |
Overexpression of human procarboxypeptidase A2 in Pichia pastoris and detailed characterization of its activation pathway D Reverter, S Ventura, V Villegas, J Vendrell, FX Avilés Journal of Biological Chemistry 273 (6), 3535-3541, 1998 | 69 | 1998 |
Molecular mechanisms in SUMO conjugation N Varejão, J Lascorz, Y Li, D Reverter Biochemical Society Transactions 48 (1), 123-135, 2020 | 63 | 2020 |
Mechanistic basis of Nek7 activation through Nek9 binding and induced dimerization T Haq, MW Richards, SG Burgess, P Gallego, S Yeoh, L O’Regan, ... Nature communications 6 (1), 8771, 2015 | 57 | 2015 |