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Isha Sethi
Isha Sethi
Postdoctoral Fellow, Boston Children's Hospital and Dana Farber Cancer Institute
Verifierad e-postadress på jimmy.harvard.edu
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Analysis of cardiac myocyte maturation using CASAAV, a platform for rapid dissection of cardiac myocyte gene function in vivo
Y Guo, NJ VanDusen, L Zhang, W Gu, I Sethi, S Guatimosim, Q Ma, ...
Circulation research 120 (12), 1874-1888, 2017
1172017
A reference map of murine cardiac transcription factor chromatin occupancy identifies dynamic and conserved enhancers
BN Akerberg, F Gu, NJ VanDusen, X Zhang, R Dong, K Li, B Zhang, ...
Nature communications 10 (1), 4907, 2019
1112019
A global analysis of the complex landscape of isoforms and regulatory networks of p63 in human cells and tissues
I Sethi, RA Romano, C Gluck, K Smalley, B Vojtesek, MJ Buck, S Sinha
BMC genomics 16, 1-15, 2015
752015
Hierarchical and stage-specific regulation of murine cardiomyocyte maturation by serum response factor
Y Guo, BD Jardin, P Zhou, I Sethi, BN Akerberg, CN Toepfer, Y Ai, Y Li, ...
Nature communications 9 (1), 3837, 2018
732018
Sarcomeres regulate murine cardiomyocyte maturation through MRTF-SRF signaling
Y Guo, Y Cao, BD Jardin, I Sethi, Q Ma, B Moghadaszadeh, EC Troiano, ...
Proceedings of the National Academy of Sciences 118 (2), e2008861118, 2021
462021
Massively parallel in vivo CRISPR screening identifies RNF20/40 as epigenetic regulators of cardiomyocyte maturation
NJ VanDusen, JY Lee, W Gu, CE Butler, I Sethi, Y Zheng, JS King, P Zhou, ...
Nature communications 12 (1), 4442, 2021
412021
Role of chromatin and transcriptional co-regulators in mediating p63-genome interactions in keratinocytes
I Sethi, S Sinha, MJ Buck
BMC genomics 15, 1-17, 2014
392014
Evolutionary re-wiring of p63 and the epigenomic regulatory landscape in keratinocytes and its potential implications on species-specific gene expression and phenotypes
I Sethi, C Gluck, H Zhou, MJ Buck, S Sinha
Nucleic acids research 45 (14), 8208-8224, 2017
382017
Reactivation of super-enhancers by KLF4 in human Head and Neck Squamous Cell Carcinoma
M Tsompana, C Gluck, I Sethi, I Joshi, J Bard, NJ Nowak, S Sinha, ...
Oncogene 39 (2), 262-277, 2020
172020
GATA4 regulates developing endocardium through interaction with ETS1
P Zhou, Y Zhang, I Sethi, L Ye, MA Trembley, Y Cao, BN Akerberg, F Xiao, ...
Circulation research 131 (11), e152-e168, 2022
92022
Molecular profiling establishes genetic features predictive of the efficacy of the p110β inhibitor KIN-193
I Sethi, Z Cai, TM Roberts, GC Yuan
Cancer research 79 (17), 4524-4531, 2019
72019
Blocking PI3K p110β Attenuates Development of PTEN-Deficient Castration-Resistant Prostate Cancer
X Gao, Y Wang, CF Ribeiro, C Manokaran, H Chang, T Von, S Rodrigues, ...
Molecular Cancer Research 20 (5), 673-685, 2022
62022
Dynamic changes in P300 enhancers and enhancer-promoter contacts control mouse cardiomyocyte maturation
P Zhou, NJ VanDusen, Y Zhang, Y Cao, I Sethi, R Hu, S Zhang, G Wang, ...
Developmental Cell 58 (10), 898-914. e7, 2023
52023
Spatial mapping of human hematopoiesis at single-cell resolution reveals aging-associated topographic remodeling
A Sarachakov, A Varlamova, V Svekolkin, M Polyakova, I Valencia, ...
Blood 142 (26), 2282-2295, 2023
32023
Sarcomeres regulate cardiomyocyte maturation through MRTF-SRF signaling
Y Guo, BD Jardin, I Sethi, Q Ma, B Moghadaszadeh, EC Troiano, ...
bioRxiv, 824185, 2019
32019
An integrated genomic approach identifies follistatin as a target of the p63-epidermal growth factor receptor oncogenic network in head and neck squamous cell carcinoma
A Oyelakin, J Sosa, KB Nayak, A Glathar, C Gluck, I Sethi, M Tsompana, ...
NAR cancer 5 (3), zcad038, 2023
12023
Transcriptomic-Based Microenvironment Classification Reveals Precision Medicine Strategies for PDAC
B George, O Kudryashova, A Kravets, S Thalji, S Malarkannan, ...
Gastroenterology, 2024
2024
Single Cell Resolution Spatial Mapping of Human Hematopoiesis Reveals Aging-Associated Topographic Remodeling
A Sarachakov, A Varlamova, V Svekolkin, I Galkin, I Valencia, ...
bioRxiv, 2023.04. 28.538715, 2023
2023
Mutual Potentiation Between Myofibril Assembly and Serum Response Factor in Cardiomyocyte Maturation
Y Guo, B Jardin, I Sethi, B Moghadaszadeh, A Beggs, W Pu
Circulation Research 125 (Suppl_1), A920-A920, 2019
2019
RNF20/40 Regulates Cardiomyocyte Maturation
NJ Vandusen, JY Lee, W Gu, I Sethi, S Suo, J King, Y Zheng, Y Guo, ...
Circulation Research 125 (Suppl_1), A658-A658, 2019
2019
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Artiklar 1–20