The CoQ oxidoreductase FSP1 acts parallel to GPX4 to inhibit ferroptosis K Bersuker, JM Hendricks, Z Li, L Magtanong, B Ford, PH Tang, ... Nature 575 (7784), 688-692, 2019 | 2090 | 2019 |
Monoacylglycerol lipase regulates a fatty acid network that promotes cancer pathogenesis DK Nomura, JZ Long, S Niessen, HS Hoover, SW Ng, BF Cravatt Cell 140 (1), 49-61, 2010 | 1084 | 2010 |
Endocannabinoid hydrolysis generates brain prostaglandins that promote neuroinflammation DK Nomura, BE Morrison, JL Blankman, JZ Long, SG Kinsey, ... Science 334 (6057), 809-813, 2011 | 751 | 2011 |
Chronic monoacylglycerol lipase blockade causes functional antagonism of the endocannabinoid system JE Schlosburg, JL Blankman, JZ Long, DK Nomura, B Pan, SG Kinsey, ... Nature neuroscience 13 (9), 1113-1119, 2010 | 688 | 2010 |
Exogenous monounsaturated fatty acids promote a ferroptosis-resistant cell state L Magtanong, PJ Ko, M To, JY Cao, GC Forcina, A Tarangelo, CC Ward, ... Cell chemical biology 26 (3), 420-432. e9, 2019 | 652 | 2019 |
Microglia dictate the impact of saturated fat consumption on hypothalamic inflammation and neuronal function M Valdearcos, MM Robblee, DI Benjamin, DK Nomura, AW Xu, ... Cell reports 9 (6), 2124-2138, 2014 | 565 | 2014 |
Inhibition of fatty acid oxidation as a therapy for MYC-overexpressing triple-negative breast cancer R Camarda, AY Zhou, RA Kohnz, S Balakrishnan, C Mahieu, B Anderton, ... Nature medicine 22 (4), 427-432, 2016 | 481 | 2016 |
Lysosomal cholesterol activates mTORC1 via an SLC38A9–Niemann-Pick C1 signaling complex BM Castellano, AM Thelen, O Moldavski, MK Feltes, REN Van Der Welle, ... Science 355 (6331), 1306-1311, 2017 | 477 | 2017 |
DGAT1-dependent lipid droplet biogenesis protects mitochondrial function during starvation-induced autophagy TB Nguyen, SM Louie, JR Daniele, Q Tran, A Dillin, R Zoncu, DK Nomura, ... Developmental cell 42 (1), 9-21. e5, 2017 | 461 | 2017 |
Dual blockade of FAAH and MAGL identifies behavioral processes regulated by endocannabinoid crosstalk in vivo JZ Long, DK Nomura, RE Vann, DM Walentiny, L Booker, X Jin, ... Proceedings of the National Academy of Sciences 106 (48), 20270-20275, 2009 | 440 | 2009 |
Supersymmetry parameter analysis: SPA convention and project JA Aguilar-Saavedra, A Ali, BC Allanach, R Arnowitt, HA Baer, JA Bagger, ... The European Physical Journal C-Particles and Fields 46, 43-60, 2006 | 400 | 2006 |
Activity-based protein profiling for biochemical pathway discovery in cancer DK Nomura, MM Dix, BF Cravatt Nature Reviews Cancer 10 (9), 630-638, 2010 | 372 | 2010 |
Characterization of monoacylglycerol lipase inhibition reveals differences in central and peripheral endocannabinoid metabolism JZ Long, DK Nomura, BF Cravatt Chemistry & biology 16 (7), 744-753, 2009 | 319 | 2009 |
Harnessing the anti-cancer natural product nimbolide for targeted protein degradation JN Spradlin, X Hu, CC Ward, SM Brittain, MD Jones, L Ou, M To, ... Nature chemical biology 15 (7), 747-755, 2019 | 312 | 2019 |
Monoacylglycerol lipase exerts dual control over endocannabinoid and fatty acid pathways to support prostate cancer DK Nomura, DP Lombardi, JW Chang, S Niessen, AM Ward, JZ Long, ... Chemistry & biology 18 (7), 846-856, 2011 | 286 | 2011 |
A proximity labeling strategy provides insights into the composition and dynamics of lipid droplet proteomes K Bersuker, CWH Peterson, M To, SJ Sahl, V Savikhin, EA Grossman, ... Developmental cell 44 (1), 97-112. e7, 2018 | 284 | 2018 |
Effective breast cancer combination therapy targeting BACH1 and mitochondrial metabolism J Lee, AE Yesilkanal, JP Wynne, C Frankenberger, J Liu, J Yan, M Elbaz, ... Nature 568 (7751), 254-258, 2019 | 271 | 2019 |
Suppressing fatty acid uptake has therapeutic effects in preclinical models of prostate cancer MJ Watt, AK Clark, LA Selth, VR Haynes, N Lister, R Rebello, LH Porter, ... Science translational medicine 11 (478), eaau5758, 2019 | 264 | 2019 |
Mitochondrial DNA replication defects disturb cellular dNTP pools and remodel one-carbon metabolism J Nikkanen, S Forsström, L Euro, I Paetau, RA Kohnz, L Wang, D Chilov, ... Cell metabolism 23 (4), 635-648, 2016 | 258 | 2016 |
Advances in covalent drug discovery L Boike, NJ Henning, DK Nomura Nature Reviews Drug Discovery 21 (12), 881-898, 2022 | 253 | 2022 |