Modulators of 14-3-3 protein–protein interactions LM Stevers, E Sijbesma, M Botta, C MacKintosh, T Obsil, I Landrieu, ... Journal of medicinal chemistry 61 (9), 3755-3778, 2017 | 242 | 2017 |
Stabilization of protein-protein interactions in drug discovery SA Andrei, E Sijbesma, M Hann, J Davis, G O’Mahony, MWD Perry, ... Expert opinion on drug discovery 12 (9), 925-940, 2017 | 152 | 2017 |
Unlock the thermogenic potential of adipose tissue: pharmacological modulation and implications for treatment of diabetes and obesity XR Peng, P Gennemark, G O’Mahony, S Bartesaghi Frontiers in endocrinology 6, 174, 2015 | 66 | 2015 |
PPARγ and PPARα synergize to induce robust browning of white fat in vivo T Kroon, M Harms, S Maurer, L Bonnet, I Alexandersson, A Lindblom, ... Molecular metabolism 36, 100964, 2020 | 59 | 2020 |
Discovering New Classes of Brugia malayi Asparaginyl-tRNA Synthetase Inhibitors and Relating Specificity to Conformational Change SCK Sukuru, T Crepin, Y Milev, LC Marsh, JB Hill, RJ Anderson, ... Journal of computer-aided molecular design 20, 159-178, 2006 | 56 | 2006 |
Identification and design of a novel series of MGAT2 inhibitors JG Barlind, LK Buckett, SG Crosby, Ö Davidsson, H Emtenäs, A Ertan, ... Bioorganic & medicinal chemistry letters 23 (9), 2721-2726, 2013 | 51 | 2013 |
Discovery of 4-hydroxy-1, 6-naphthyridine-3-carbonitrile derivatives as novel PDE10A inhibitors U Bauer, F Giordanetto, M Bauer, G O’Mahony, KE Johansson, W Knecht, ... Bioorganic & medicinal chemistry letters 22 (5), 1944-1948, 2012 | 34 | 2012 |
Synthesis of tertiary amides from anionically activated aromatic trifluoromethyl groups G O’Mahony, AK Pitts Organic Letters 12 (9), 2024-2027, 2010 | 27 | 2010 |
Rapid stereoselective access to key pumiliotoxin precursors from a common intermediate G O'Mahony, M Nieuwenhuyzen, P Armstrong, PJ Stevenson The Journal of Organic Chemistry 69 (11), 3968-3971, 2004 | 27 | 2004 |
Synthesis of adenosine-based fluorosides containing a novel heterocyclic ring system G O’Mahony, E Ehrman, M Grøtli Tetrahedron letters 46 (39), 6745-6748, 2005 | 25 | 2005 |
Design of Drug‐Like Protein–Protein Interaction Stabilizers Guided By Chelation‐Controlled Bioactive Conformation Stabilization F Bosica, SA Andrei, JF Neves, P Brandt, A Gunnarsson, I Landrieu, ... Chemistry–A European Journal 26 (31), 7131-7139, 2020 | 23 | 2020 |
NMR-based substrate analog docking to Escherichia coli peptidyl-tRNA hydrolase L Giorgi, P Plateau, G O'Mahony, C Aubard, M Fromant, A Thureau, ... Journal of molecular biology 412 (4), 619-633, 2011 | 20 | 2011 |
Synthesis and photophysical properties of novel cyclonucleosides—substituent effects on fluorescence emission G O'Mahony, E Ehrman, M Grøtli Tetrahedron 64 (30-31), 7151-7158, 2008 | 20 | 2008 |
In vivo liposomal delivery of PPARα/γ dual agonist tesaglitazar in a model of obesity enriches macrophage targeting and limits liver and kidney drug effects V Osinski, DK Bauknight, SSK Dasa, MJ Harms, T Kroon, MA Marshall, ... Theranostics 10 (2), 585, 2020 | 19 | 2020 |
Identification of mineralocorticoid receptor modulators with low impact on electrolyte homeostasis but maintained organ protection KL Granberg, ZQ Yuan, B Lindmark, K Edman, J Kajanus, A Hogner, ... Journal of Medicinal Chemistry 62 (3), 1385-1406, 2018 | 19 | 2018 |
Phosphorylated full‐length Tau interacts with 14‐3‐3 proteins via two short phosphorylated sequences, each occupying a binding groove of 14‐3‐3 dimer JF Neves, O Petrvalská, F Bosica, FX Cantrelle, H Merzougui, ... The FEBS Journal 288 (6), 1918-1934, 2021 | 14 | 2021 |
A Revised Structure for Alkaloid 235C Isolated from Skin Extracts of Mantellid (Mantella) Frogs of Madagascar NR Andriamaharavo, M Andriantsiferana, PA Stevenson, G O'mahony, ... Journal of natural products 68 (12), 1743-1748, 2005 | 14 | 2005 |
Triethylborane (Et3B) G O’Mahony Synlett 2004 (03), 572-573, 2004 | 14 | 2004 |
Structure‐Based Drug Design of Mineralocorticoid Receptor Antagonists to Explore Oxosteroid Receptor Selectivity A Nordqvist, G O'Mahony, M Fridén‐Saxin, M Fredenwall, A Hogner, ... ChemMedChem 12 (1), 50-65, 2017 | 13 | 2017 |
The small molecule SERCA activator CDN1163 increases energy metabolism in human skeletal muscle cells AM Mengeste, J Lund, P Katare, R Ghobadi, HG Bakke, PK Lunde, L Eide, ... Current research in pharmacology and drug discovery 2, 100060, 2021 | 11 | 2021 |