Isaac Klein

Citeras av

	Alla	Sedan 2019
Citat	6923	5136
h-index	23	19
i10-index	25	24

1300

650

325

975

2008200920102011201220132014201520162017201820192020202120222023202440 31 68 136 195 290 250 233 161 165 187 487 736 1125 1192 1232 362

Offentlig åtkomst

Visa alla

25 artiklar

1 artikel

tillgänglig

inte tillgänglig

Enligt krav från finansiärer

Medförfattare

Richard YoungProfessor of Biology, MITVerifierad e-postadress på wi.mit.edu
michel nussenzweigHHMI, The Rockefeller UniversityVerifierad e-postadress på rockefeller.edu
Eliot L. CoffeyMITVerifierad e-postadress på wi.mit.edu
Jurian SchuijersAssistant Professor at Center for Molecular Medicine, UMC UtrechtVerifierad e-postadress på umcutrecht.nl
Alessandra Dall'AgneseWhitehead InstituteVerifierad e-postadress på wi.mit.edu
Benjamin R. SabariAssistant Professor, UT Southwestern Medical CenterVerifierad e-postadress på utsouthwestern.edu
Alicia Viridiana ZamudioGenentech, Inc.Verifierad e-postadress på gene.com
John C. ManteigaScientist at Dewpoint TherapeuticsVerifierad e-postadress på dewpointtherapeutics.com
Lena AfeyanPhD Student, Massachusetts Institute of TechnologyVerifierad e-postadress på mit.edu
Krishna ShrinivasAssistant Professor, Northwestern UniversityVerifierad e-postadress på northwestern.edu
Charles H. LiChoate, Hall & Stewart LLPVerifierad e-postadress på choate.com
mila jankovicsenior research associateVerifierad e-postadress på rockefeller.edu
andre NussenzweignihVerifierad e-postadress på nih.gov
Davide F. Robbiani, MD, PhDInstitute for Research in Biomedicine, Università della Svizzera italianaVerifierad e-postadress på irb.usi.ch
Thiago Yukio Kikuchi OliveiraRockefeller UniversityVerifierad e-postadress på rockefeller.edu
Daniel DayPostdoctoral Fellow, Whitehead InstituteVerifierad e-postadress på mit.edu
Ibrahim CisséMax Planck Institute, FreiburgVerifierad e-postadress på ie-freiburg.mpg.de
Robert RoederProfessor of Biochemistry and Molecular Biology, The Rockefeller UniversityVerifierad e-postadress på rockefeller.edu
Denes HniszMax Planck Institute for Molecular GeneticsVerifierad e-postadress på molgen.mpg.de
Ozgur OksuzWhitehead InstituteVerifierad e-postadress på wi.mit.edu

Följ

Isaac Klein

Dewpoint Therapeutics

Verifierad e-postadress på dewpointx.com

Cancer Biology Oncology Condensate Biology Drug Discovery Gene Regulation


Titel Sortera efter citat Sortera efter år Sortera efter titel	Citeras av Citeras av	År
Coactivator condensation at super-enhancers links phase separation and gene control BR Sabari, A Dall’Agnese, A Boija, IA Klein, EL Coffey, K Shrinivas, ... Science 361 (6400), eaar3958, 2018	1871	2018
Transcription factors activate genes through the phase-separation capacity of their activation domains A Boija, IA Klein, BR Sabari, A Dall’Agnese, EL Coffey, AV Zamudio, ... Cell 175 (7), 1842-1855. e16, 2018	1334	2018
Activation-induced cytidine deaminase targets DNA at sites of RNA polymerase II stalling by interaction with Spt5 R Pavri, A Gazumyan, M Jankovic, M Di Virgilio, I Klein, ... Cell 143 (1), 122-133, 2010	408	2010
Translocation-capture sequencing reveals the extent and nature of chromosomal rearrangements in B lymphocytes IA Klein, W Resch, M Jankovic, T Oliveira, A Yamane, H Nakahashi, ... Cell 147 (1), 95-106, 2011	381	2011
Rag mutations reveal robust alternative end joining B Corneo, RL Wendland, L Deriano, X Cui, IA Klein, SY Wong, S Arnal, ... Nature 449 (7161), 483-486, 2007	377	2007
Partitioning of cancer therapeutics in nuclear condensates IA Klein, A Boija, LK Afeyan, SW Hawken, M Fan, A Dall'Agnese, O Oksuz, ... Science 368 (6497), 1386-1392, 2020	314	2020
AID produces DNA double-strand breaks in non-Ig genes and mature B cell lymphomas with reciprocal chromosome translocations DF Robbiani, S Bunting, N Feldhahn, A Bothmer, J Camps, S Deroubaix, ... Molecular cell 36 (4), 631-641, 2009	312	2009
Enhancer features that drive formation of transcriptional condensates K Shrinivas, BR Sabari, EL Coffey, IA Klein, A Boija, AV Zamudio, ... Molecular cell 75 (3), 549-561. e7, 2019	309	2019
Regulation of DNA end joining, resection, and immunoglobulin class switch recombination by 53BP1 A Bothmer, DF Robbiani, M Di Virgilio, SF Bunting, IA Klein, N Feldhahn, ... Molecular cell 42 (3), 319-329, 2011	265	2011
DNA damage defines sites of recurrent chromosomal translocations in B lymphocytes O Hakim, W Resch, A Yamane, I Klein, KR Kieffer-Kwon, M Jankovic, ... Nature 484 (7392), 69-74, 2012	225	2012
Mediator condensates localize signaling factors to key cell identity genes AV Zamudio, A Dall’Agnese, JE Henninger, JC Manteiga, LK Afeyan, ... Molecular cell 76 (5), 753-766. e6, 2019	201	2019
Biomolecular condensates and cancer A Boija, IA Klein, RA Young Cancer cell 39 (2), 174-192, 2021	185	2021
lncRNA DIGIT and BRD3 protein form phase-separated condensates to regulate endoderm differentiation K Daneshvar, MB Ardehali, IA Klein, FK Hsieh, AJ Kratkiewicz, A Mahpour, ... Nature cell biology 22 (10), 1211-1222, 2020	118	2020
Modulating biomolecular condensates: a novel approach to drug discovery DM Mitrea, M Mittasch, BF Gomes, IA Klein, MA Murcko Nature Reviews Drug Discovery 21 (11), 841-862, 2022	110	2022
Class switching and meiotic defects in mice lacking the E3 ubiquitin ligase RNF8 MA Santos, MSY Huen, M Jankovic, HT Chen, AJ López-Contreras, ... Journal of Experimental Medicine 207 (5), 973-981, 2010	107	2010
Translocation capture sequencing: a method for high throughput mapping of chromosomal rearrangements TY Oliveira, W Resch, M Jankovic, R Casellas, MC Nussenzweig, IA Klein Journal of immunological methods 375 (1-2), 176-181, 2012	75	2012
Activation-induced cytidine deaminase in antibody diversification and chromosome translocation A Gazumyan, A Bothmer, IA Klein, MC Nussenzweig, KM McBride Advances in cancer research 113, 167-190, 2012	56	2012
High-throughput sequencing reveals principles of adeno-associated virus serotype 2 integration T Janovitz, IA Klein, T Oliveira, P Mukherjee, MC Nussenzweig, ... Journal of virology 87 (15), 8559-8568, 2013	46	2013
Predicting master transcription factors from pan-cancer expression data J Reddy, MAS Fonseca, RI Corona, R Nameki, F Segato Dezem, IA Klein, ... Science advances 7 (48), eabf6123, 2021	42	2021
53BP1 alters the landscape of DNA rearrangements and suppresses AID-induced B cell lymphoma M Jankovic, N Feldhahn, TY Oliveira, IT Silva, KR Kieffer-Kwon, ... Molecular cell 49 (4), 623-631, 2013	38	2013

Systemet kan inte utföra åtgärden just nu. Försök igen senare.

Artiklar 1–20

Citat per år

Dubblettcitat

Sammanfogade citat

Lägg till medförfattareMedförfattare

Följ

Citeras av

Medförfattare