Julian D. Hegemann
Julian D. Hegemann
Verifierad e-postadress på campus.tu-berlin.de - Startsida
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Lasso peptides: an intriguing class of bacterial natural products
JD Hegemann, M Zimmermann, X Xie, MA Marahiel
Accounts of chemical research 48 (7), 1909-1919, 2015
1842015
Lasso peptides from proteobacteria: Genome mining employing heterologous expression and mass spectrometry
JD Hegemann, M Zimmermann, S Zhu, D Klug, MA Marahiel
Peptide Science 100 (5), 527-542, 2013
942013
Caulosegnins I–III: a highly diverse group of lasso peptides derived from a single biosynthetic gene cluster
JD Hegemann, M Zimmermann, X Xie, MA Marahiel
Journal of the American Chemical Society 135 (1), 210-222, 2013
922013
The astexin-1 lasso peptides: biosynthesis, stability, and structural studies
M Zimmermann, JD Hegemann, X Xie, MA Marahiel
Chemistry & biology 20 (4), 558-569, 2013
712013
Xanthomonins I–III: A New Class of Lasso Peptides with a Seven‐Residue Macrolactam Ring
JD Hegemann, M Zimmermann, S Zhu, H Steuber, K Harms, X Xie, ...
Angewandte Chemie International Edition 53 (8), 2230-2234, 2014
702014
Rational improvement of the affinity and selectivity of integrin binding of grafted lasso peptides
JD Hegemann, M De Simone, M Zimmermann, TA Knappe, X Xie, ...
Journal of Medicinal Chemistry 57 (13), 5829-5834, 2014
632014
Insights into the unique phosphorylation of the lasso peptide paeninodin
S Zhu, JD Hegemann, CD Fage, M Zimmermann, X Xie, U Linne, ...
Journal of Biological Chemistry 291 (26), 13662-13678, 2016
622016
The PqqD homologous domain of the radical SAM enzyme ThnB is required for thioether bond formation during thurincin H maturation
BM Wieckowski, JD Hegemann, A Mielcarek, L Boss, O Burghaus, ...
FEBS letters 589 (15), 1802-1806, 2015
582015
Ion mobility–mass spectrometry of lasso peptides: signature of a rotaxane topology
K Jeanne Dit Fouque, C Afonso, S Zirah, JD Hegemann, M Zimmermann, ...
Analytical chemistry 87 (2), 1166-1172, 2015
442015
Characterization of caulonodin lasso peptides revealed unprecedented N-terminal residues and a precursor motif essential for peptide maturation
M Zimmermann, JD Hegemann, X Xie, MA Marahiel
Chemical Science 5 (10), 4032-4043, 2014
412014
The B1 protein guides the biosynthesis of a lasso peptide
S Zhu, CD Fage, JD Hegemann, A Mielcarek, D Yan, U Linne, ...
Scientific reports 6, 35604, 2016
392016
The ring residue proline 8 is crucial for the thermal stability of the lasso peptide caulosegnin II
JD Hegemann, CD Fage, S Zhu, K Harms, FS Di Leva, E Novellino, ...
Molecular BioSystems 12 (4), 1106-1109, 2016
292016
Structural basis for natural product selection and export by bacterial ABC transporters
M Romano, G Fusco, HG Choudhury, S Mehmood, CV Robinson, S Zirah, ...
ACS chemical biology 13 (6), 1598-1609, 2018
192018
Structural basis for natural product selection and export by bacterial ABC transporters
M Romano, G Fusco, HG Choudhury, S Mehmood, CV Robinson, S Zirah, ...
ACS chemical biology 13 (6), 1598-1609, 2018
192018
Identification of lasso peptide topologies using native nanoelectrospray ionization-trapped ion mobility spectrometry–mass spectrometry
KJ Dit Fouque, J Moreno, JD Hegemann, S Zirah, S Rebuffat, ...
Analytical chemistry 90 (8), 5139-5146, 2018
182018
Enterobacter bugandensis: a novel enterobacterial species associated with severe clinical infection
NB Pati, SP Doijad, T Schultze, GK Mannala, Y Yao, S Jaiswal, D Ryan, ...
Scientific reports 8 (1), 5392, 2018
172018
Elucidation of the roles of conserved residues in the biosynthesis of the lasso peptide paeninodin
JD Hegemann, CJ Schwalen, DA Mitchell, WA Van der Donk
Chemical Communications 54 (65), 9007-9010, 2018
162018
Structure and mechanism of the sphingopyxin I lasso peptide isopeptidase
CD Fage, JD Hegemann, AJ Nebel, RM Steinbach, S Zhu, U Linne, ...
Angewandte Chemie 128 (41), 12909-12913, 2016
162016
Investigation of the Biosynthesis of the Lasso Peptide Chaxapeptin Using an E. coli-Based Production System
H Martin-Gómez, U Linne, F Albericio, J Tulla-Puche, JD Hegemann
Journal of natural products 81 (9), 2050-2056, 2018
152018
Signatures of mechanically interlocked topology of lasso peptides by ion mobility–mass spectrometry: lessons from a collection of representatives
KJD Fouque, H Lavanant, S Zirah, JD Hegemann, M Zimmermann, ...
Journal of The American Society for Mass Spectrometry 28 (2), 315-322, 2016
152016
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Artiklar 1–20