| Generation of quinolone antimalarials targeting the Plasmodium falciparum mitochondrial respiratory chain for the treatment and prophylaxis of malaria GA Biagini, N Fisher, AE Shone, MA Mubaraki, A Srivastava, A Hill, ... Proceedings of the National Academy of Sciences 109 (21), 8298-8303, 2012 | 193 | 2012 |
| Antimalarial 4(1H)-pyridones bind to the Qi site of cytochrome bc1 MJ Capper, PM O’Neill, N Fisher, RW Strange, D Moss, SA Ward, ... Proceedings of the National Academy of Sciences 112 (3), 755-760, 2015 | 123 | 2015 |
| Cytochrome b mutation Y268S conferring atovaquone resistance phenotype in malaria parasite results in reduced parasite bc1 catalytic turnover and protein expression N Fisher, R Abd Majid, T Antoine, M Al-Helal, AJ Warman, DJ Johnson, ... Journal of Biological Chemistry 287 (13), 9731-9741, 2012 | 112 | 2012 |
| HDQ, a Potent Inhibitor of Plasmodium falciparum Proliferation, Binds to the Quinone Reduction Site of the Cytochrome bc1 Complex C Vallières, N Fisher, T Antoine, M Al-Helal, P Stocks, NG Berry, ... Antimicrobial agents and chemotherapy 56 (7), 3739-3747, 2012 | 70 | 2012 |
| Thiazolides as novel antiviral agents. 2. Inhibition of hepatitis C virus replication AV Stachulski, C Pidathala, EC Row, R Sharma, NG Berry, AS Lawrenson, ... Journal of medicinal chemistry 54 (24), 8670-8680, 2011 | 50 | 2011 |
| The development of quinolone esters as novel antimalarial agents targeting the Plasmodium falciparum bc 1 protein complex R Cowley, S Leung, N Fisher, M Al-Helal, NG Berry, AS Lawrenson, ... MedChemComm 3 (1), 39-44, 2012 | 46 | 2012 |
| Identification of novel antimalarial chemotypes via chemoinformatic compound selection methods for a high-throughput screening program against the novel malarial target, PfNDH2 … R Sharma, AS Lawrenson, NE Fisher, AJ Warman, AE Shone, A Hill, ... Journal of medicinal chemistry 55 (7), 3144-3154, 2012 | 32 | 2012 |
| Study of the antimalarial activity of 4-aminoquinoline compounds against chloroquine-sensitive and chloroquine-resistant parasite strains AS Lawrenson, DL Cooper, PM O’Neill, NG Berry Journal of molecular modeling 24, 1-11, 2018 | 31 | 2018 |
| Abacavir forms novel cross-linking abacavir protein adducts in patients X Meng, AS Lawrenson, NG Berry, JL Maggs, NS French, DJ Back, ... Chemical research in toxicology 27 (4), 524-535, 2014 | 31 | 2014 |
| Molecular Mechanism of Action of Antimalarial Benzoisothiazolones: Species-Selective Inhibitors of the Plasmodium spp. MEP Pathway enzyme, IspD KE Price, CM Armstrong, LS Imlay, DM Hodge, C Pidathala, NJ Roberts, ... Scientific reports 6 (1), 36777, 2016 | 25 | 2016 |
| Towards depersonalized abacavir therapy: chemical modification eliminates HLA-B:*: 57: 01-restricted CD8:+: T-cell activation DJ Naisbitt, EL Yang, M Alhaidari, NG Berry, AS Lawrenson, J Farrell, ... Aids 29 (18), 2385-2395, 2015 | 22 | 2015 |
| 2-Pyridylquinolone antimalarials with improved antimalarial activity and physicochemical properties S Charoensutthivarakul, WD Hong, SC Leung, PD Gibbons, ... MedChemComm 6 (7), 1252-1259, 2015 | 19 | 2015 |
| Measured dose dispensers and methods of using the same CW Skillin, JE Scotton US Patent 10,471,452, 2019 | 4 | 2019 |
| ChemTube3D interactive 3D organic reaction mechanisms A Lawrenson, K Barnes, N Greeves ChemTube3D, 2008 | 2 | 2008 |
| Antimalarial 4 (1H)-pyridones bind to the Qᵢ site of cytochrome bc₁ MJ Capper, PM O’Neill, N Fisher, RW Strange, D Moss, SA Ward, ... | | 2015 |
| Antimalarial compounds P O'neill, G Biagini, SA Ward, NG Berry, G Nixon, RK Amewu, C Pidathala, ... | | 2012 |
| Antimalarial drug design: targeting the plasmodium falciparum cytochrome bc1 complex through computational modelling, chemical synthesis and biological testing A Lawrenson University of Liverpool, 2012 | | 2012 |
| Antimalarial compounds RK Amewu, NG Berry, G Biagini, P Gibbons, WD Hong, AS Lawrenson, ... WO Patent App. PCT/GB2011/052,345, 2011 | | 2011 |
| Full wwPDB X-ray Structure Validation Report i MJ Capper, GSA Wright, SV Antonyuk, SS Hasnain | | |
| CONCISE ARTICLE S Charoensutthivarakul, WD Hong, SC Leung, PD Gibbons, ... | | |
