| A systems-level analysis of the peripheral nerve intrinsic axonal growth program V Chandran, G Coppola, H Nawabi, T Omura, R Versano, EA Huebner, ... Neuron 89 (5), 956-970, 2016 | 349 | 2016 |
| Breaking barriers to novel analgesic drug development AS Yekkirala, DP Roberson, BP Bean, CJ Woolf Nature reviews Drug discovery 16 (8), 545-564, 2017 | 346 | 2017 |
| Bivalent Ligands That Target μ Opioid (MOP) and Cannabinoid1 (CB1) Receptors Are Potent Analgesics Devoid of Tolerance M Le Naour, E Akgün, A Yekkirala, MM Lunzer, MD Powers, ... Journal of medicinal chemistry 56 (13), 5505-5513, 2013 | 93 | 2013 |
| Targeting CYP2J to reduce paclitaxel-induced peripheral neuropathic pain M Sisignano, C Angioni, CK Park, S Meyer Dos Santos, H Jordan, ... Proceedings of the National Academy of Sciences 113 (44), 12544-12549, 2016 | 91 | 2016 |
| N-naphthoyl-β-naltrexamine (NNTA), a highly selective and potent activator of μ/κ-opioid heteromers AS Yekkirala, MM Lunzer, CR McCurdy, MD Powers, AE Kalyuzhny, ... Proceedings of the National Academy of Sciences 108 (12), 5098-5103, 2011 | 81 | 2011 |
| Standard Opioid Agonists Activate Heteromeric Opioid Receptors: Evidence for Morphine and [d-Ala2-MePhe4-Glyol5]Enkephalin as Selective μ−δ Agonists AS Yekkirala, AE Kalyuzhny, PS Portoghese ACS chemical neuroscience 1 (2), 146-154, 2010 | 70 | 2010 |
| A bivalent ligand (KMN-21) antagonist for μ/κ heterodimeric opioid receptors S Zhang, A Yekkirala, Y Tang, PS Portoghese Bioorganic & medicinal chemistry letters 19 (24), 6978-6980, 2009 | 59 | 2009 |
| Clinically employed opioid analgesics produce antinociception via μ-δ opioid receptor heteromers in Rhesus monkeys AS Yekkirala, ML Banks, MM Lunzer, SS Negus, KC Rice, PS Portoghese ACS Chemical Neuroscience 3 (9), 720-727, 2012 | 46 | 2012 |
| Basic/translational development of forthcoming opioid-and nonopioid-targeted pain therapeutics NN Knezevic, A Yekkirala, TL Yaksh Anesthesia & Analgesia 125 (5), 1714-1732, 2017 | 44 | 2017 |
| Differential association rule mining for the study of protein-protein interaction networks C Besemann, A Denton, A Yekkirala Proceedings of the 4th International Conference on Data Mining in …, 2004 | 39 | 2004 |
| The δ opioid receptor agonist SNC80 selectively activates heteromeric μ–δ opioid receptors MD Metcalf, AS Yekkirala, MD Powers, KF Kitto, CA Fairbanks, GL Wilcox, ... ACS Chemical Neuroscience 3 (7), 505-509, 2012 | 36 | 2012 |
| An immunocytochemical-derived correlate for evaluating the bridging of heteromeric mu-delta opioid protomers by bivalent ligands AS Yekkirala, AE Kalyuzhny, PS Portoghese ACS chemical biology 8 (7), 1412-1416, 2013 | 35 | 2013 |
| Two to tango: GPCR oligomers and GPCR-TRP channel interactions in nociception AS Yekkirala Life sciences 92 (8-9), 438-445, 2013 | 32 | 2013 |
| Naloxone acts as a potent analgesic in transgenic mouse models of sickle cell anemia MM Lunzer, A Yekkirala, RP Hebbel, PS Portoghese Proceedings of the National Academy of Sciences 104 (14), 6061-6065, 2007 | 32 | 2007 |
| Vagal sensory neurons drive mucous cell metaplasia S Talbot, B Doyle, J Huang, JC Wang, M Ahmadi, DP Roberson, ... Journal of allergy and clinical immunology 145 (6), 1693-1696. e4, 2020 | 22 | 2020 |
| Reduced MC4R signaling alters nociceptive thresholds associated with red hair KC Robinson, LV Kemény, GL Fell, AL Hermann, J Allouche, W Ding, ... Science Advances 7 (14), eabd1310, 2021 | 9 | 2021 |
| Opioid receptors in analgesic drug design–the past, present and future AS Yekkirala J. of Postdoctoral Research 1 (4), 9-23, 2013 | 5 | 2013 |
| Analgesic agents PS Portoghese, AS Yekkirala US Patent 8,609,682, 2013 | 2 | 2013 |
| Differential association rules: understanding annotations in protein interaction networks C Besemann, A Denton, A Yekkirala, R Hutchison, M Anderson Advanced Data Mining Technologies in Bioinformatics, 269-282, 2006 | 2 | 2006 |
| Bortezomib-induced neuropathy is in part mediated by the sensitization of TRPV1 channels JM Sprague, AS Yekkirala, B Singh, I Tochitsky, M Stephens, ... Communications biology 6 (1), 1228, 2023 | 1 | 2023 |
clifford woolfBoston Children's HopsitalVerified email at childrens.harvard.edu
