Fer-mediated cortactin phosphorylation is associated with efficient fibroblast migration and is dependent on reactive oxygen species generation during integrin-mediated cell … W Sangrar, Y Gao, M Scott, P Truesdell, PA Greer Molecular and cellular biology 27 (17), 6140-6152, 2007 | 96 | 2007 |
Apolipoprotein (a) enhances platelet responses to the thrombin receptor–activating peptide SFLLRN ML Rand, W Sangrar, MA Hancock, DM Taylor, SM Marcovina, ... Arteriosclerosis, thrombosis, and vascular biology 18 (9), 1393-1399, 1998 | 92 | 1998 |
Antifibrinolytic effect of recombinant apolipoprotein (a) in vitro is primarily due to attenuation of tPA-mediated Glu-plasminogen activation W Sangrar, L Bajzar, ME Nesheim, ML Koschinsky Biochemistry 34 (15), 5151-5157, 1995 | 88 | 1995 |
Apolipoprotein (a) attenuates endogenous fibrinolysis in the rabbit jugular vein thrombosis model in vivo BJ Biemond, PW Friederich, ML Koschinsky, M Levi, W Sangrar, J Xia, ... Circulation 96 (5), 1612-1615, 1997 | 81 | 1997 |
The solution phase interaction between apolipoprotein (a) and plasminogen inhibits the binding of plasminogen to a plasmin-modified fibrinogen surface W Sangrar, BR Gabel, MB Boffa, JB Walker, MA Hancock, SM Marcovina, ... Biochemistry 36 (34), 10353-10363, 1997 | 72 | 1997 |
Binding of recombinant apolipoprotein (a) to extracellular matrix proteins. YY van der Hoek, W Sangrar, GP Cote, JJ Kastelein, ML Koschinsky Arteriosclerosis and Thrombosis: A Journal of Vascular Biology 14 (11), 1792 …, 1994 | 70 | 1994 |
Flavopiridol synergizes with sorafenib to induce cytotoxicity and potentiate antitumorigenic activity in EGFR/HER-2 and mutant RAS/RAF breast cancer model systems TS Nagaria, JL Williams, C Leduc, JA Squire, PA Greer, W Sangrar Neoplasia 15 (8), 939-IN27, 2013 | 47 | 2013 |
Expression and characterization of apolipoprotein (a) kringle IV types 1, 2 and 10 in mammalian cells W Sangrar, SM Marcovina, ML Koschinsky Protein Engineering, Design and Selection 7 (5), 723-731, 1994 | 47 | 1994 |
An identity crisis for fps/fes: oncogene or tumor suppressor? W Sangrar, RA Zirgnibl, Y Gao, WJ Muller, Z Jia, PA Greer Cancer research 65 (9), 3518-3522, 2005 | 44 | 2005 |
Fps/Fes and Fer non-receptor protein-tyrosine kinases regulate collagen-and ADP-induced platelet aggregation YA Senis, W Sangrar, RA Zirngibl, AWB Craig, DH Lee, PA Greer Journal of Thrombosis and Haemostasis 1 (5), 1062-1070, 2003 | 36 | 2003 |
Combined targeting of Raf and Mek synergistically inhibits tumorigenesis in triple negative breast cancer model systems TS Nagaria, C Shi, C Leduc, V Hoskin, S Sikdar, W Sangrar, PA Greer Oncotarget 8 (46), 80804, 2017 | 35 | 2017 |
Amplified Ras-MAPK signal states correlate with accelerated EGFR internalization, cytostasis and delayed HER2 tumor onset in Fer-deficient model systems W Sangrar, C Shi, G Mullins, D LeBrun, B Ingalls, PA Greer Oncogene 34 (31), 4109-4117, 2015 | 33 | 2015 |
Integration, visualization and analysis of human interactome C Pastrello, E Pasini, M Kotlyar, D Otasek, S Wong, W Sangrar, S Rahmati, ... Biochemical and biophysical research communications 445 (4), 757-773, 2014 | 33 | 2014 |
The fps/fes proto-oncogene regulates hematopoietic lineage output W Sangrar, Y Gao, RA Zirngibl, ML Scott, PA Greer Experimental hematology 31 (12), 1259-1267, 2003 | 24 | 2003 |
Automated quantitative analysis of p53, Cyclin D1, Ki67 and pERK expression in breast carcinoma does not differ from expert pathologist scoring and correlates with clinico … JD Cass, S Varma, AG Day, W Sangrar, AB Rajput, LH Raptis, J Squire, ... Cancers 4 (3), 725-742, 2012 | 22 | 2012 |
Characterization of the interaction of recombinant apolipoprotein (a) with modified fibrinogen surfaces and fibrin clots W Sangrar, ML Koschinsky Biochemistry and Cell Biology 78 (4), 519-525, 2000 | 22 | 2000 |
Vascular defects in gain‐of‐function fps/festransgenic mice correlate with PDGF‐and VEGF‐induced activation of mutant Fps/Fes kinase in endothelial cells W Sangrar, JD Mewburn, SG Vincent, JT Fisher, PA Greer Journal of Thrombosis and Haemostasis 2 (5), 820-832, 2004 | 19 | 2004 |
Activated Fps/Fes tyrosine kinase regulates erythroid differentiation and survival W Sangrar, Y Gao, B Bates, R Zirngibl, PA Greer Experimental hematology 32 (10), 935-945, 2004 | 18 | 2004 |
fps/fes knockout mice display a lactation defect and the fps/fes tyrosine kinase is a component of E-cadherin-based adherens junctions in breast epithelial cells during lactation PF Truesdell, RA Zirngibl, S Francis, W Sangrar, PA Greer Experimental cell research 315 (17), 2929-2940, 2009 | 14 | 2009 |
Petri net siphon analysis and graph theoretic measures for identifying combination therapies in cancer B Behinaein, K Rudie, W Sangrar IEEE/ACM Transactions on Computational Biology and Bioinformatics 15 (1 …, 2016 | 12 | 2016 |