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| PI3K/AKT signaling pathway and cancer: an updated review M Martini, MC De Santis, L Braccini, F Gulluni, E Hirsch Annals of medicine 46 (6), 372-383, 2014 | 1142 | 2014 |
| Blockade of PI3Kγ suppresses joint inflammation and damage in mouse models of rheumatoid arthritis M Camps, T Rückle, H Ji, V Ardissone, F Rintelen, J Shaw, C Ferrandi, ... Nature medicine 11 (9), 936-943, 2005 | 902 | 2005 |
| Non-redundant role of the long pentraxin PTX3 in anti-fungal innate immune response C Garlanda, E Hirsch, S Bozza, A Salustri, M De Acetis, R Nota, ... Nature 420 (6912), 182-186, 2002 | 822 | 2002 |
| Regulation of myocardial contractility and cell size by distinct PI3K-PTEN signaling pathways MA Crackower, GY Oudit, I Kozieradzki, R Sarao, H Sun, T Sasaki, ... Cell 110 (6), 737-749, 2002 | 785 | 2002 |
| PI3Kγ modulates the cardiac response to chronic pressure overload by distinct kinase-dependent and-independent effects E Patrucco, A Notte, L Barberis, G Selvetella, A Maffei, M Brancaccio, ... Cell 118 (3), 375-387, 2004 | 602 | 2004 |
| PTX3 plays a key role in the organization of the cumulus oophorus extracellular matrix and in in vivo fertilization A Salustri, C Garlanda, E Hirsch, M De Acetis, A Maccagno, B Bottazzi, ... Oxford University Press for The Company of Biologists Limited 131 (7), 1577-1586, 2004 | 526 | 2004 |
| Cardiovascular side effects of cancer therapies: a position statement from the Heart Failure Association of the European Society of Cardiology T Eschenhagen, T Force, MS Ewer, GW De Keulenaer, TM Suter, ... European journal of heart failure 13 (1), 1-10, 2011 | 499 | 2011 |
| Spatiotemporal control of endocytosis by phosphatidylinositol-3, 4-bisphosphate Y Posor, M Eichhorn-Gruenig, D Puchkov, J Schöneberg, A Ullrich, ... Nature 499 (7457), 233-237, 2013 | 448 | 2013 |
| Impaired migration but not differentiation of haematopoietic stem cells in the absence of β1 integrins E Hirsch, A Iglesias, AJ Potocnik, U Hartmann, R Fässler Nature 380 (6570), 171-175, 1996 | 433 | 1996 |
| Inflammation as a therapeutic target in heart failure? A scientific statement from the Translational Research Committee of the Heart Failure Association of the European Society … S Heymans, E Hirsch, SD Anker, P Aukrust, JL Balligand, ... European journal of heart failure 11 (2), 119-129, 2009 | 431 | 2009 |
| Macrophage-secreted granulin supports pancreatic cancer metastasis by inducing liver fibrosis SR Nielsen, V Quaranta, A Linford, P Emeagi, C Rainer, A Santos, ... Nature cell biology 18 (5), 549-560, 2016 | 411 | 2016 |
| Receptor tyrosine kinases and TLR/IL1Rs unexpectedly activate myeloid cell PI3kγ, a single convergent point promoting tumor inflammation and progression MC Schmid, CJ Avraamides, HC Dippold, I Franco, P Foubert, LG Ellies, ... Cancer cell 19 (6), 715-727, 2011 | 410 | 2011 |
| Phosphoinositide 3-kinase γ is an essential amplifier of mast cell function M Laffargue, R Calvez, P Finan, A Trifilieff, M Barbier, F Altruda, E Hirsch, ... Immunity 16 (3), 441-451, 2002 | 391 | 2002 |
| Sequential activation of class IB and class IA PI3K is important for the primed respiratory burst of human but not murine neutrophils AM Condliffe, K Davidson, KE Anderson, CD Ellson, T Crabbe, ... Blood 106 (4), 1432-1440, 2005 | 384 | 2005 |
| Melusin, a muscle-specific integrin β1–interacting protein, is required to prevent cardiac failure in response to chronic pressure overload M Brancaccio, L Fratta, A Notte, E Hirsch, R Poulet, S Guazzone, ... Nature medicine 9 (1), 68-75, 2003 | 357 | 2003 |
| Intestinal inflammation in mice deficient in Tir8, an inhibitory member of the IL-1 receptor family C Garlanda, F Riva, N Polentarutti, C Buracchi, M Sironi, M De Bortoli, ... Proceedings of the National Academy of Sciences 101 (10), 3522-3526, 2004 | 309 | 2004 |
| PI (3) Kγ has an important context-dependent role in neutrophil chemokinesis GJ Ferguson, L Milne, S Kulkarni, T Sasaki, S Walker, S Andrews, ... Nature cell biology 9 (1), 86-91, 2007 | 297 | 2007 |
| Phosphoinositide 3-kinase p110β activity: key role in metabolism and mammary gland cancer but not development E Ciraolo, M Iezzi, R Marone, S Marengo, C Curcio, C Costa, O Azzolino, ... Science signaling 1 (36), ra3-ra3, 2008 | 294 | 2008 |
| Resistance to thromboembolism in PI3Kγ‐deficient mice E Hirsch, O Bosco, P Tropel, M Laffargue, R Calvez, F Altruda, ... The FASEB Journal 15 (11), 2019-2021, 2001 | 280 | 2001 |
Cecilia GarlandaCapo Laboratorio, Istituto Clinico HumanitasVerified email at humanitasresearch.it
