| Improving the phenotype predictions of a yeast genome‐scale metabolic model by incorporating enzymatic constraints BJ Sánchez, C Zhang, A Nilsson, PJ Lahtvee, EJ Kerkhoven, J Nielsen Molecular systems biology 13 (8), 935, 2017 | 134 | 2017 |
| Regulation of amino-acid metabolism controls flux to lipid accumulation in Yarrowia lipolytica EJ Kerkhoven, KR Pomraning, SE Baker, J Nielsen NPJ systems biology and applications 2, 16005, 2016 | 97 | 2016 |
| Probing the metabolic network in bloodstream-form Trypanosoma brucei using untargeted metabolomics with stable isotope labelled glucose DJ Creek, M Mazet, F Achcar, J Anderson, DH Kim, R Kamour, P Morand, ... PLoS pathogens 11 (3), e1004689, 2015 | 86 | 2015 |
| RAVEN 2.0: A versatile toolbox for metabolic network reconstruction and a case study on Streptomyces coelicolor H Wang, S Marcišauskas, BJ Sánchez, I Domenzain, D Hermansson, ... PLOS Computational Biology 14 (10), e1006541, 2018 | 63 | 2018 |
| Barriers and opportunities in bio-based production of hydrocarbons YJ Zhou, EJ Kerkhoven, J Nielsen Nature Energy 3 (11), 925-935, 2018 | 62 | 2018 |
| Applications of computational modeling in metabolic engineering of yeast EJ Kerkhoven, PJ Lahtvee, J Nielsen FEMS Yeast Res 15 (1), 1-13, 2015 | 50 | 2015 |
| A domino effect in drug action: from metabolic assault towards parasite differentiation JR Haanstra, EJ Kerkhoven, A Van Tuijl, M Blits, M Wurst, R Van Nuland, ... Molecular microbiology 79 (1), 94-108, 2011 | 50 | 2011 |
| Genome scale metabolic modeling of the riboflavin overproducer Ashbya gossypii R Ledesma‐Amaro, EJ Kerkhoven, JL Revuelta, J Nielsen Biotechnology and bioengineering 111 (6), 1191-1199, 2014 | 45 | 2014 |
| Handling uncertainty in dynamic models: the pentose phosphate pathway in Trypanosoma brucei EJ Kerkhoven, F Achcar, VP Alibu, RJ Burchmore, IH Gilbert, M Trybiło, ... PLoS computational biology 9 (12), e1003371, 2013 | 41 | 2013 |
| An atlas of human metabolism JL Robinson, P Kocabaş, H Wang, PE Cholley, D Cook, A Nilsson, ... Science Signaling 13 (624), 2020 | 39 | 2020 |
| Dynamic modelling under uncertainty: the case of Trypanosoma brucei energy metabolism F Achcar, EJ Kerkhoven, BM Bakker, MP Barrett, R Breitling, ... PLoS computational biology 8 (1), e1002352, 2012 | 37 | 2012 |
| Genome‐scale metabolic model of Pichia pastoris with native and humanized glycosylation of recombinant proteins ZA Irani, EJ Kerkhoven, SA Shojaosadati, J Nielsen Biotechnology and bioengineering 113 (5), 961-969, 2016 | 36 | 2016 |
| A consensus S. cerevisiae metabolic model Yeast8 and its ecosystem for comprehensively probing cellular metabolism H Lu, F Li, BJ Sánchez, Z Zhu, G Li, I Domenzain, S Marcišauskas, ... Nature Communications 10 (1), 1-13, 2019 | 35 | 2019 |
| A molecular genetic toolbox for Yarrowia lipolytica EL Bredeweg, KR Pomraning, Z Dai, J Nielsen, EJ Kerkhoven, SE Baker Biotechnology for biofuels 10 (1), 2, 2017 | 32 | 2017 |
| Leucine biosynthesis is involved in regulating high lipid accumulation in Yarrowia lipolytica EJ Kerkhoven, YM Kim, S Wei, CD Nicora, TL Fillmore, SO Purvine, ... MBio 8 (3), e00857-17, 2017 | 27 | 2017 |
| TrypanoCyc: a community-led biochemical pathways database for Trypanosoma brucei S Shameer, FJ Logan-Klumpler, F Vinson, L Cottret, B Merlet, F Achcar, ... Nucleic acids research 43 (D1), D637-D644, 2014 | 25 | 2014 |
| Advancing metabolic engineering of Yarrowia lipolytica using the CRISPR/Cas system TQ Shi, H Huang, EJ Kerkhoven, XJ Ji Applied microbiology and biotechnology 102 (22), 9541-9548, 2018 | 24 | 2018 |
| Proteome analysis of xylose metabolism in Rhodotorula toruloides during lipid production IA Tiukova, J Brandenburg, J Blomqvist, S Sampels, N Mikkelsen, ... Biotechnology for Biofuels 12 (1), 137, 2019 | 18 | 2019 |
| Crystal Structure of an Arginase-like Protein from Trypanosoma brucei That Evolved without a Binuclear Manganese Cluster Y Hai, EJ Kerkhoven, MP Barrett, DW Christianson Biochemistry 54 (2), 458-471, 2014 | 18 | 2014 |
| Genome‐scale model of Rhodotorula toruloides metabolism IA Tiukova, S Prigent, J Nielsen, M Sandgren, EJ Kerkhoven Biotechnology and bioengineering 116 (12), 3396-3408, 2019 | 14 | 2019 |
Jens NielsenProfessor in Systems Biology, Chalmers University of Technology, SwedenVerified email at chalmers.se
